12,421 research outputs found

    Research requirements to reduce maintenance costs of civil helicopters

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    The maintenance problems faced by the operators of civil helicopters that result in high costs are documented. Existing technology that can be applied to reduce maintenance costs and research that should be carried out were identified. Good design practice and application of existing technology were described as having a significant impact on reducing maintenance costs immediately. The research and development that have potential for long range reduction of maintenance costs are presented

    Invariant manifolds and orbit control in the solar sail three-body problem

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    In this paper we consider issues regarding the control and orbit transfer of solar sails in the circular restricted Earth-Sun system. Fixed points for solar sails in this system have the linear dynamical properties of saddles crossed with centers; thus the fixed points are dynamically unstable and control is required. A natural mechanism of control presents itself: variations in the sail's orientation. We describe an optimal controller to control the sail onto fixed points and periodic orbits about fixed points. We find this controller to be very robust, and define sets of initial data using spherical coordinates to get a sense of the domain of controllability; we also perform a series of tests for control onto periodic orbits. We then present some mission strategies involving transfer form the Earth to fixed points and onto periodic orbits, and controlled heteroclinic transfers between fixed points on opposite sides of the Earth. Finally we present some novel methods to finding periodic orbits in circumstances where traditional methods break down, based on considerations of the Center Manifold theorem

    Autoclavable addition polyimides for 371 C composite applications

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    Studies were conducted to improve the thermo-oxidative stability (TOS) of PMR type polyimides by the substitution of para-aminostyrene (PAS) for the nadic ester endcap in second generation PMR polyimides (PMR-2). The nadic endcap which provides the PMR polyimides with their relative ease of fabrication, both by limiting the molecular weight of the prepolymer and by undergoing the final addition cure without volatiles, is also the weak link with regard to TOS. A polyimide formulated with PAS endcaps, called V-CAP, utilizes a two step reaction sequence similar to that of the PMR polyimides and can be easily autoclave molded into low void composite materials. Resin studies included two formulations of both PMR-2 and V-CAP, corresponding to n=9 and n=14 prepolymer stoichiometry. Unidirectional reinforced T40R graphite fiber laminates were fabricated from each of the resins was post-cured in either air at 385 C or nitrogen at 400 C. Composite specimens were aged in air at 371 C and mechanical properties were measured at 371 C before and after exposure

    Modelling crystal aggregation and deposition\ud in the catheterised lower urinary tract

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    Urethral catheters often become encrusted with crystals of magnesium struvite and calcium phosphate. The encrustation can block the catheter, which can cause urine retention in the bladder and reflux into the kidneys. We develop a mathematical model to investigate crystal deposition on the catheter surface, modelling the bladder as a reservoir of fluid and the urethral catheter as a rigid channel. At a constant rate, fluid containing crystal particles of unit size enters the reservoir, and flows from the reservoir through the channel and out of the system. The crystal particles aggregate, which we model using Becker–Döring coagulation theory, and are advected through the channel, where they continue to aggregate and are deposited on the channel’s walls. Inhibitor particles also enter the reservoir, and can bind to the crystals, preventing further aggregation and deposition. The crystal concentrations are spatially homogeneous in the reservoir, whereas the channel concentrations vary spatially as a result of advection, diffusion and deposition. We investigate the effect of inhibitor particles on the amount of deposition. For all parameter values, we find that crystals deposit along the full length of the channel, with maximum deposition close to the channel’s entrance

    The changing face of chemotherapy in colorectal cancer

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    The interplay between tissue growth and scaffold degradation in engineered tissue constructs

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    In vitro tissue engineering is emerging as a potential tool to meet the high demand for replacement tissue, caused by the increased incidence of tissue degeneration and damage. A key challenge in this field is ensuring that the mechanical properties of the engineered tissue are appropriate for the in vivo environment. Achieving this goal will require detailed understanding of the interplay between cell proliferation, extracellular matrix (ECM) deposition and scaffold degradation.\ud \ud In this paper, we use a mathematical model (based upon a multiphase continuum framework) to investigate the interplay between tissue growth and scaffold degradation during tissue construct evolution in vitro. Our model accommodates a cell population and culture medium, modelled as viscous fluids, together with a porous scaffold and ECM deposited by the cells, represented as rigid porous materials. We focus on tissue growth within a perfusion bioreactor system, and investigate how the predicted tissue composition is altered under the influence of (i) differential interactions between cells and the supporting scaffold and their associated ECM, (ii) scaffold degradation, and (iii) mechanotransduction-regulated cell proliferation and ECM deposition.\ud \ud Numerical simulation of the model equations reveals that scaffold heterogeneity typical of that obtained from μCT scans of tissue engineering scaffolds can lead to significant variation in the flow-induced mechanical stimuli experienced by cells seeded in the scaffold. This leads to strong heterogeneity in the deposition of ECM. Furthermore, preferential adherence of cells to the ECM in favour of the artificial scaffold appears to have no significant influence on the eventual construct composition; adherence of cells to these supporting structures does, however, lead to cell and ECM distributions which mimic and exaggerate the heterogeneity of the underlying scaffold. Such phenomena have important ramifications for the mechanical integrity of engineered tissue constructs and their suitability for implantation in vivo

    Equivalence-based Security for Querying Encrypted Databases: Theory and Application to Privacy Policy Audits

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    Motivated by the problem of simultaneously preserving confidentiality and usability of data outsourced to third-party clouds, we present two different database encryption schemes that largely hide data but reveal enough information to support a wide-range of relational queries. We provide a security definition for database encryption that captures confidentiality based on a notion of equivalence of databases from the adversary's perspective. As a specific application, we adapt an existing algorithm for finding violations of privacy policies to run on logs encrypted under our schemes and observe low to moderate overheads.Comment: CCS 2015 paper technical report, in progres

    An asymptotic theory for the re-equilibration of a micellar surfactant solution

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    Micellar surfactant solutions are characterized by a distribution of aggregates comprised predominantly of pre-micellar aggregates (monomers, dimers, trimers, etc.) and a region of proper micelles close to the peak aggregation number, connected by an intermediate region containing a very low concentration of aggregates. Such a distribution gives rise to a distinct two-timescale re-equilibration following a system dilution, known as the 1 and 2 processes, whose dynamics may be described by the Becker–Döring equations. We use a continuum version of these equations to develop a reduced asymptotic description that elucidates the behavior during each of these processes

    Potential applications of digital, visible, and infrared data from geostationary environmental satellites

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    An hourly, digital data base from the Visible/Infrared Spin-Scan Radiometer (VISSR) instrument on the GOES-1 and SMS-2 geostationary satellites is described. Several examples of developmental applications of these quantitative digital data are presented. These include a review of recent attempts to develop products that are of use to meteorologists who provide services to aviation, agriculture, forestry, hydrology, oceanography, and climatology. The sample products include high resolution thermal gradients of land and ocean surfaces, thermal change analyses, fruit frost/freeze application, cloud-top altitude analysis, analysis of hurricane characteristics, and analyses of solar insolation

    On the predictions and limitations of the BeckerDoring model for reaction kinetics in micellar surfactant solutions

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    We investigate the breakdown of a system of micellar aggregates in a surfactant solution following an order-one dilution. We derive a mathematical model based on the Becker–Döring system of equations, using realistic expressions for the reaction constants fit to Molecular Dynamics simulations. We exploit the largeness of typical aggregation numbers to derive a continuum model, substituting a large system of ordinary differential equations for a partial differential equation in two independent variables: time and aggregate size. Numerical solutions demonstrate that re-equilibration occurs in two distinct stages over well-separated time-scales, in agreement with experiment and with previous theories. We conclude by exposing a limitation in the Becker–Döring theory for re-equilibration and discuss potential resolutions
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