1,191 research outputs found
Report on Second Activations with the Lead Slowing Down Spectrometer
Summary On August 18 and 19 2011, five items were irradiated with neutrons using the Lead Slowing Down Spectrometer (LSDS). After irradiation, dose measurements and gamma-spectrometry measurements were completed on all of the samples. No contamination was found on the samples, and all but one provided no dose. Gamma-spectroscopy measurements qualitatively agreed with expectations based on the materials. As during the first activation run, we observed activation in the room in general, mostly due to 56Mn and 24Na. Most of the activation of the samples was short lived, with half-lives on the scale of hours to days, except for 60Co which has a half-life of 5.3 y
Crustal shortening, exhumation, and strain localization in a collisional orogen: the Bajo Pequeño Shear Zone, Sierra de Pie de Palo, Argentina
The Bajo Pequeño Shear Zone (BPSZ) is a lower-crustal shear zone that records shortening and exhumation associated with the establishment of a new plate boundary, and its placement in a regional structural context suggests that local- to regional-scale strain localization occurred with progressive deformation. A kilometer-scale field and analytical cross section through the ~80 m thick BPSZ and its adjacent rocks indicates an early Devonian (405–400 Ma) phase of deformation on the western margin of Gondwanan continental crust. The earliest stages of the BPSZ, recorded by metamorphic and microstructural data, involved thrusting of a hotter orthogneiss over a relatively cool pelitic unit, which resulted in footwall garnet growth and reset footwall white mica 40Ar/39Ar ages in proximity to the shear zone. Later stages of BPSZ activity, as recorded by additional microstructures and quartz c-axis opening angles, were characterized by strain localization to the center of the shear zone coincident with cooling and exhumation. These and other data suggest that significant regional tectonism persisted in the Famatinian orogenic system for 60–70 million years after one microplate collision (the Precordillera) but ceased 5–10 million years prior to another (Chilenia). A survey of other synchronous structures shows that strain was accommodated on progressively narrower structures with time, indicating a regional pattern of strain localization and broad thermal relaxation as the Precordillera collision evolved.Fil: Garber, Joshua M.. University of California at Davis; Estados UnidosFil: Roeske, Sarah M.. University of California at Davis; Estados UnidosFil: Warren, Jessica. University of Stanford; Estados UnidosFil: Mulcahy, Sean R.. University of California at Berkeley; Estados UnidosFil: McClelland, William C.. University of Iowa; Estados UnidosFil: Austin, Lauren J.. University of Oregon; Estados UnidosFil: Renne, Paul R.. University of California at Berkeley; Estados UnidosFil: Vujovich, Graciela Irene. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de GeologÃa. Laboratorio de Tectónica Andina; Argentina. Consejo Nacional de Investigaciones CientÃficas y Técnicas; Argentin
Crustal Shortening, Exhumation, and Strain Localization in a Collisonal Orogen: the Bajo Pequeno Shear Zone, Sierra de Pie de Palo, Argentina
The Bajo Pequeño Shear Zone (BPSZ) is a lower-crustal shear zone that records shortening and exhumation associated with the establishment of a new plate boundary, and its placement in a regional structural context suggests that local- to regional-scale strain localization occurred with progressive deformation. A kilometer-scale field and analytical cross section through the ~80 m thick BPSZ and its adjacent rocks indicates an early Devonian (405–400 Ma) phase of deformation on the western margin of Gondwanan continental crust. The earliest stages of the BPSZ, recorded by metamorphic and microstructural data, involved thrusting of a hotter orthogneiss over a relatively cool pelitic unit, which resulted in footwall garnet growth and reset footwall white mica 40Ar/39Ar ages in proximity to the shear zone. Later stages of BPSZ activity, as recorded by additional microstructures and quartz c-axis opening angles, were characterized by strain localization to the center of the shear zone coincident with cooling and exhumation. These and other data suggest that significant regional tectonism persisted in the Famatinian orogenic system for 60–70 million years after one microplate collision (the Precordillera) but ceased 5–10 million years prior to another (Chilenia). A survey of other synchronous structures shows that strain was accommodated on progressively narrower structures with time, indicating a regional pattern of strain localization and broad thermal relaxation as the Precordillera collision evolved
Application of ultrafast gold luminescence to measuring the instrument response function for multispectral multiphoton fluorescence lifetime imaging
When performing multiphoton fluorescence lifetime imaging in multiple spectral emission channels, an instrument response function must be acquired in each channel if accurate measurements of complex fluorescence decays are to be performed. Although this can be achieved using the reference reconvolution technique, it is difficult to identify suitable fluorophores with a mono-exponential fluorescence decay across a broad emission spectrum. We present a solution to this problem by measuring the IRF using the ultrafast luminescence from gold nanorods. We show that ultrafast gold nanorod luminescence allows the IRF to be directly obtained in multiple spectral channels simultaneously across a wide spectral range. We validate this approach by presenting an analysis of multispectral autofluorescence FLIM data obtained from human skin ex vivo
Intravital FRAP imaging using an E-cadherin-GFP mouse reveals disease- and drug-dependent dynamic regulation of cell-cell junctions in live tissue
E-cadherin-mediated cell-cell junctions play a prominent role in maintaining the epithelial architecture. The disruption or deregulation of these adhesions in cancer can lead to the collapse of tumor epithelia that precedes invasion and subsequent metastasis. Here we generated an E-cadherin-GFP mouse that enables intravital photobleaching and
quantification of E-cadherin mobility in live tissue without affecting normal biology. We demonstrate the broad applications of this mouse by examining
E-cadherin regulation in multiple tissues, including mammary, brain, liver, and kidney tissue, while specifically monitoring E-cadherin mobility during
disease progression in the pancreas. We assess E-cadherin stability in native pancreatic tissue upon genetic manipulation involving Kras and p53
or in response to anti-invasive drug treatment and gain insights into the dynamic remodeling of E-cadherin during in situ cancer progression. FRAP in the E-cadherin-GFP mouse, therefore, promises to be a valuable tool to fundamentally expand our understanding of E-cadherin-mediated events in native microenvironments
A cryogenic rotation stage with a large clear aperture for the half-wave plates in the Spider instrument
We describe the cryogenic half-wave plate rotation mechanisms built for and
used in Spider, a polarization-sensitive balloon-borne telescope array that
observed the Cosmic Microwave Background at 95 GHz and 150 GHz during a
stratospheric balloon flight from Antarctica in January 2015. The mechanisms
operate at liquid helium temperature in flight. A three-point contact design
keeps the mechanical bearings relatively small but allows for a large (305 mm)
diameter clear aperture. A worm gear driven by a cryogenic stepper motor allows
for precise positioning and prevents undesired rotation when the motors are
depowered. A custom-built optical encoder system monitors the bearing angle to
an absolute accuracy of +/- 0.1 degrees. The system performed well in Spider
during its successful 16 day flight.Comment: 11 pages, 7 figures, Published in Review of Scientific Instruments.
v2 includes reviewer changes and longer literature revie
Modeling and characterization of the SPIDER half-wave plate
Spider is a balloon-borne array of six telescopes that will observe the
Cosmic Microwave Background. The 2624 antenna-coupled bolometers in the
instrument will make a polarization map of the CMB with approximately one-half
degree resolution at 145 GHz. Polarization modulation is achieved via a
cryogenic sapphire half-wave plate (HWP) skyward of the primary optic. We have
measured millimeter-wave transmission spectra of the sapphire at room and
cryogenic temperatures. The spectra are consistent with our physical optics
model, and the data gives excellent measurements of the indices of A-cut
sapphire. We have also taken preliminary spectra of the integrated HWP, optical
system, and detectors in the prototype Spider receiver. We calculate the
variation in response of the HWP between observing the CMB and foreground
spectra, and estimate that it should not limit the Spider constraints on
inflation
Pointing control for the SPIDER balloon-borne telescope
We present the technology and control methods developed for the pointing
system of the SPIDER experiment. SPIDER is a balloon-borne polarimeter designed
to detect the imprint of primordial gravitational waves in the polarization of
the Cosmic Microwave Background radiation. We describe the two main components
of the telescope's azimuth drive: the reaction wheel and the motorized pivot. A
13 kHz PI control loop runs on a digital signal processor, with feedback from
fibre optic rate gyroscopes. This system can control azimuthal speed with <
0.02 deg/s RMS error. To control elevation, SPIDER uses stepper-motor-driven
linear actuators to rotate the cryostat, which houses the optical instruments,
relative to the outer frame. With the velocity in each axis controlled in this
way, higher-level control loops on the onboard flight computers can implement
the pointing and scanning observation modes required for the experiment. We
have accomplished the non-trivial task of scanning a 5000 lb payload
sinusoidally in azimuth at a peak acceleration of 0.8 deg/s, and a peak
speed of 6 deg/s. We can do so while reliably achieving sub-arcminute pointing
control accuracy.Comment: 20 pages, 12 figures, Presented at SPIE Ground-based and Airborne
Telescopes V, June 23, 2014. To be published in Proceedings of SPIE Volume
914
- …