Prediction techniques for jet-induced effects in hover on STOVL aircraft

Prediction techniques for jet induced lift effects during hover are available, relatively easy to use, and produce adequate results for preliminary design work. Although deficiencies of the current method were found, it is still currently the best way to estimate jet induced lift effects short of using computational fluid dynamics. Its use is summarized. The new summarized method, represents the first step toward the use of surface pressure data in an empirical method, as opposed to just balance data in the current method, for calculating jet induced effects. Although the new method is currently limited to flat plate configurations having two circular jets of equal thrust, it has the potential of more accurately predicting jet induced effects including a means for estimating the pitching moment in hover. As this method was developed from a very limited amount of data, broader applications of the method require the inclusion of new data on additional configurations. However, within this small data base, the new method does a better job in predicting jet induced effects in hover than the current method

Communications Decency Act Provides No Safe Harbor Against Antifraud Liability for Hyperlinks to Third-Party Content under the Securities and Exchange Act

In 2008, the U.S. Securities and Exchange Commission (SEC) released interpretive guidelines regarding antifraud liability for statements and disclosures made on company Web sites. The SEC noted that a company may incur both criminal and civil liability under section 10(b) of the Securities Exchange Act and Rule 10b-5 for hyperlinks to third-party content. However, the Communications Decency Act, 47 U.S.C. § 230(c), expressly preempts civil liability for interactive computer service providers that post hyperlinks to third-party content on their Web sites. This Article examines whether section 230 immunizes companies from civil liability for hyperlinks to third-party content despite the SEC’s interpretive guidelines imposing antifraud liability. This Article concludes that companies would likely be considered information content providers under section 230 and therefore outside the scope of the safe harbor provision for interactive computer service providers

Land Grant Application- Wardwell, Joseph (Rumford)

Land grant application submitted to the Maine Land Office for Joseph Wardwell for service in the Revolutionary War.https://digitalmaine.com/revolutionary_war_me_land_office/1932/thumbnail.jp

Invalidity of Covenants Not to Compete in California Affects Employers Nationwide

In Edwards v. Arthur Andersen LLP, the Supreme Court of California rejected the Ninth Circuit Court of Appeals’ “narrow restraint” exception to California Business and Professional Code section 16600 regarding the unenforceability of covenants not to compete (CNCs). Edwards affirms that, unless the agreement falls within a statutory exception, CNCs in employment agreements are invalid as a matter of law in California because of California\u27s strong interest in protecting employee mobility as codified in section 16600. Despite California’s strong public policy against CNCs, an employee who wins the race to a California courthouse may not necessarily benefit from section 16600 if the employee was not a California resident or employed by a Californian employer at the time she agreed to a CNC. This Article evaluates California law and the resolution of the conflict of law issues that arise between California and other states more willing to enforce CNCs

Control of Inflammation Using Drug Delivery Strategies in in vitro Models

Regulation of inflammation is a crucial component of the immune system in response to injury and infection. In otherwise healthy individuals, an initial acute inflammatory response will subside once the injury or infection is eradicated. However, in certain disease states including autoimmune disease and persistent infection, miscommunication between cells of the immune system leads to a chronic inflammatory response, contributing to disease pathology and exacerbating symptoms. A major regulator of inflammation communication at the cellular level is transcription factor (TF) NF-κB. Under normal conditions, NF-κB is bound to an inhibitor in the cytoplasm. In a chronic disease state, NF-κB is overactive and found in the unbound form, resulting in increased production of inflammatory signals. Transcription factor decoys (TFD) are small nucleic acid sequences (~20 base pairs) that mimic the binding site for the TF on the native DNA, but do not encode for any proteins. By binding to the TF in the cytoplasm, TFD have potential to limit excessive immune signaling and inflammatory protein production. Unfortunately, clinical success of TFD has been hampered by a lack of an effective delivery method. Lack of stability and ease of degradation of the TFD require a protective carrier for delivery; however many synthetic carrier systems induce toxicity or an enhanced inflammatory response. In disease states characterized by excessive inflammation, treatment-induced toxicity or immune response is highly undesirable. The Bader lab has previously reported a nanoparticle carrier system based on natural polysaccharides, designed specifically for the treatment of rheumatoid arthritis. The materials used in this system have properties that can be exploited for the additional application of DNA delivery. This thesis will detail the adaptation of polysialic acid-N-trimethyl chitosan nanoparticles to be used as delivery vehicles for an NF-κB TFD treatment in in vitro models of rheumatoid arthritis and cystic fibrosis

Offshore vertical datum separations derived from Post-Processed Kinematic (PPK) heights observed along a scheduled ferry route

Eight months of GPS data were used to determine tidal constituents along a ferry route across the Bay of Fundy, Canada. The GPS data were aggregated into 62 spatial zones and analyzed as if all the data within each zone were from a single Virtual Tide Gauge (VTG). Tidal models were developed from the VTG data using a weighted least-squares solution. Chart Datum with respect to the ITRF2000 was computed for each spatial zone using 8 months of predicted water-levels. The time between ferry crossings results in sampling intervals longer than the tide signal in the Bay of Fundy, thus traditional methods of harmonic analysis are not applicable. Instead, a priori knowledge of the tide signal at each end of the ferry route is used to overcome the large and non-uniform sampling intervals. The results were confirmed by a close match between Mean Seal Level and the local Geoid

Analysis of Indianapolis waterways for evidence of eutrophication and contamination induced by urban pollution

The focus of my research will be largely focused on the water quality of the White River throughout Indianapolis. I will be testing water samples from five different points along the White River to analyze three of its contents, assessing the differing levels of pollution along different points progressing down the river and through the city. The locations I have chosen to test coincide with water gauge sites along the White River and are as follows: Logan Street in Noblesville, 82nd Street, Broad Ripple Dam, Michigan Road and Raymond Street. The surface water at these five locations will be tested every two weeks during the fall and winter to control for season change and analyze quality differences between seasons. Nitrogen and Phosphorus contents will be measured and compared to national quality standards for evidence of eutrophication induced by human disruption. Evidence of Escherichia coli through total and fecal coliform testing will also be measured and compared to national quality standards in determining the severity of sewage backup in the White River. Nitrogen and Orthophosphate concentrations did not vary significantly. Total and Fecal coliform concentrations were significantly higher at the Logan St location in Noblesville. This could be explained by the effects of agricultural runoff from nearby farms, larger amounts of CSO in this area or a combination of both

The Triumph of Chiropractic - and Then What?

The evolution of chiropractic from a marginal health profession to the strongest and most popular alternative to orthodox medicine in the United States is examined and compared with osteopathy and naturopathy. Evidence is offered that 1974 was the landmark year for recognition of chiropractors (e.g., accreditation of colleges, reimbursement for services under Medicare) and relaxation of the American Medical Association\u27s policy of active and overt opposition (e.g., elimination from its code of ethics of the tabu on professional association. The public policy question of the future status of chiropractors is raised and alternatives considered. It is concluded that the most likely outcome, as well as the best for all concerned, is for chiropractic to evolve to a limited medical professional status comparable to that of dentistry, podiatry, optometry, and psychology