62 research outputs found
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Session A2 - Fish Migration Day
Free migration of fish is necessary to achieve healthy fish stocks. Several species, including salmon, sea trout, sturgeon and eel, migrate between the sea and rivers. These species are particularly threatened by barriers such as weirs, dams and sluices, built for water management, hydropower and land drainage. Water and nature managers in Europe have been improving the situation with fish passes and by-pass channels around barriers, to help fish on their journey. An essential aspect of working on fish passage issues is raising awareness and creating commitment within communities in the different river basins. By creating commitment on all levels of the communities and stakeholders measures can be carried out more efficiently and financial opportunity can be maximised. The Fish Migration Day is a new concept to achieve greater understanding and community involvement (including children and parents). The first Fish Migration Day was held on the 14th of May 2011. The event was organized by the Living North Sea Project, which is funded by the European Union. On more than 25 locations in 7 countries in the North Sea Region interested children and parents could learn about a variety of topics, including: different species of fish, fish passage solutions, water and nature management issues, fisheries, research, aquatic insects and could play the Eel Game (www.elyeel.eu). At the end of the day 5000 persons had visited the event and it turned out to be a big success. The idea is to organize a follow up worldwide in 2013/2014. The presentation will highlight the goals, activities and results of the Fish Migration Day and will give an insight in the plans for World Fish Migration Day in 2013/2014
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Session E8: Fish Migration Possibilities in the Netherlands; State of the Art (Barriers, Solutions, Monitoring)
Abstract:
Measures to restore fish migration is gaining a major boost in the Netherlands since the Water Framework Directive, Benelux Regulation and Eel Directive are operational. Water managers, responsible for a good ecological status, are working hard to reach free fish migration in their waters.
Currently, 1.124 measures are realized at barriers like weirs, pumping stations, sluices and culverts. 2.745 barriers are identified. Since 2000, there is a strong development of measures and new techniques.
These results are based on a study “The Netherlands living with Fish Migration”, that was started in 2008. Target of this study was the evaluation of the progress in approach of measures and to gather information on improvement of fish migration in the Netherlands. Within this project a database was created with the prioritized barriers and measures for fish migration. This data is supplied by the water managers. Every four years water managers are asked for an update and an evaluation is carried out.
In this presentation the results are discussed, with focus on type of barrier, solutions and intensity of monitoring carried out by the water managers. Also an overview of planning, with respect to WFD targets, is given. A map is created of for migratory fish accessible inland waters in up- and downstream direction. Database and maps are good medium for exchanging knowledge between water managers and other stakeholders
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Dam removal Europe: refuting myths and supporting professionals
The removal of dams and weirs has been happening for decades. Since the 90’s a few countries have increased this tendency. USA has already removed at least 1,300 dams. What very few people know is that in Europe there have been over 3,500 barriers demolished already.
In some European countries, like France, Sweden, Spain, Finland and UK dams are mainly being removed due to existing legislation, safety and security, the need to reach a good ecological status of their rivers for the Water Frame Directive and/or economical reasons. However, the lack of awareness, knowledge, support by decision makers and funding for dam removal are generally bottlenecks and most of the times is the cause of many dam removal failures. In addition, the Renewable Energy Directive requires the EU countries to fulfil at least 20% of its total energy needs with renewables by 2020, and amongst these renewables is hydropower. All this makes dam removal projects tremendously difficult to those who are willing to start removing old and useless dams, and automatically makes dam removal an uncomfortable subject to bring up for politicians.
Europe requires a shift towards adaptive management of stream barriers, one that maximizes benefits and minimizes impacts, one that keeps efficient dams and removes obsolete and abandoned dams. The goals of Dam Removal Europe (www.damremoval.eu) are to improve citizens’ awareness about removing dams and refute myths, create a reference community of professionals, experts and starters, who generates and shares knowledge about dam removal and putting dam removal on the agenda of policy makers, directors and managers
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Evaluating the Effect of Therapeutic Stem Cells on TRAIL Resistant and Sensitive Medulloblastomas
Mesenchymal stem cells (MSC) are emerging as novel cell-based delivery agents; however, a thorough investigation addressing their therapeutic potential in medulloblastomas (MB) has not been explored to date. In this study, we engineered human MSC to express a potent and secretable variant of a tumor specific agent, tumor necrosis factor-apoptosis-inducing ligand (S-TRAIL) and assessed the ability of MSC-S-TRAIL mediated MB killing alone or in combination with a small molecule inhibitor of histone-deacetylase, MS-275, in TRAIL-sensitive and -resistant MB in vitro and in vivo. We show that TRAIL sensitivity/resistance correlates with the expression of its cognate death receptor (DR)5 and MSC-S-TRAIL induces caspase-3 mediated apoptosis in TRAIL-sensitive MB lines. In TRAIL-resistant MB, we show upregulation of DR4/5 levels when pre-treated with MS-275 and a subsequent sensitization to MSC-S-TRAIL mediated apoptosis. Using intracranially implanted MB and MSC lines engineered with different combinations of fluorescent and bioluminescent proteins, we show that MSC-S-TRAIL has significant anti-tumor effects in mice bearing TRAIL-sensitive and MS-275 pre-treated TRAIL-resistant MBs. To our knowledge, this is the first study that explores the use of human MSC as MB-targeting therapeutic-vehicles in vivo in TRAIL-sensitive and resistant tumors, and has implications for developing effective therapies for patients with medulloblastomas
Recommended from our members
Dam removal Europe: refuting myths and supporting professionals
The removal of dams and weirs has been happening for decades. Since the 90’s a few countries have increased this tendency. USA has already removed at least 1,300 dams. What very few people know is that in Europe there have been over 3,500 barriers demolished already.
In some European countries, like France, Sweden, Spain, Finland and UK dams are mainly being removed due to existing legislation, safety and security, the need to reach a good ecological status of their rivers for the Water Frame Directive and/or economical reasons. However, the lack of awareness, knowledge, support by decision makers and funding for dam removal are generally bottlenecks and most of the times is the cause of many dam removal failures. In addition, the Renewable Energy Directive requires the EU countries to fulfil at least 20% of its total energy needs with renewables by 2020, and amongst these renewables is hydropower. All this makes dam removal projects tremendously difficult to those who are willing to start removing old and useless dams, and automatically makes dam removal an uncomfortable subject to bring up for politicians.
Europe requires a shift towards adaptive management of stream barriers, one that maximizes benefits and minimizes impacts, one that keeps efficient dams and removes obsolete and abandoned dams. The goals of Dam Removal Europe (www.damremoval.eu) are to improve citizens’ awareness about removing dams and refute myths, create a reference community of professionals, experts and starters, who generates and shares knowledge about dam removal and putting dam removal on the agenda of policy makers, directors and managers
Systeemverkenning Drentse Aa
Voor het project ¿Meerjarig monitoringsprogramma naar de uit- en afspoeling van nutriënten vanuit landbouwgronden in stroomgebieden en polders¿ is in 2003 gestart met een systeemverkenning van het stroomgebied de Drentse Aa. Daarbij zijn van dit systeem beschikbare gegevens, relevante processen en het functioneren geïnventariseerd. Het stroomgebied van het beekstelsel de Drentse Aa is een onder natuurlijk verval afwaterend gebied, met een continu watervoerend stelsel, en behoort tot een gebied met één van de laagste nutriëntenconcentraties in Nederland. Uit de systeemverkenning kunnen de volgende conclusies worden getrokken: - Regionale transportprocessen (kwel) zijn relevant in het stroomgebied. De kwel vormt de zogenaamde langzame component van de waterafvoer van de beek. Het is daarom van belang om het diepe grondwater (regionaal grondwatersysteem) in het modelsysteem te betrekken. - Als (belangrijkste) bronnen van nutriëntenbelasting van het grond- en oppervlaktewatersysteem kunnen de posten atmosferische depositie, kwel en landbouw worden onderscheiden. Over zowel de bijdrage van de nutriëntenbelasting vanuit kwel als de belasting vanuit landbouw was ten tijde van de systeemverkenning geen informatie aanwezig om deze bronnen getalsmatig te benoemen. - Door het ontbreken van informatie over de bronnen kwel en landbouw is het niet mogelijk een relatie aan te kunnen tonen tussen gemeten nutriëntenconcentraties in het oppervlaktewater en (veranderingen van) de verschillende bronnen van nutriënten in het stroomgebied. Hierdoor is het niet mogelijk om aan te tonen of met het bestaande meetnet van het stroomgebied de effecten van het mestbeleid zichtbaar gemaakt kunnen worden. - Om het mestbeleid te kunnen evalueren is het noodzakelijk een andere manier van monitoren (meten én modelleren) te introduceren. Hierbij kan de bijdrage van iedere bron, welke binnen een gebied zijn gedefinieerd, worden geanalyseer
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