411 research outputs found
Symbiotic Bright Solitary Wave Solutions of Coupled Nonlinear Schrodinger Equations
Conventionally, bright solitary wave solutions can be obtained in
self-focusing nonlinear Schrodinger equations with attractive self-interaction.
However, when self-interaction becomes repulsive, it seems impossible to have
bright solitary wave solution. Here we show that there exists symbiotic bright
solitary wave solution of coupled nonlinear Schrodinger equations with
repulsive self-interaction but strongly attractive interspecies interaction.
For such coupled nonlinear Schrodinger equations in two and three dimensional
domains, we prove the existence of least energy solutions and study the
location and configuration of symbiotic bright solitons. We use Nehari's
manifold to construct least energy solutions and derive their asymptotic
behaviors by some techniques of singular perturbation problems.Comment: to appear in Nonlinearit
A 3D Model of the Membrane Protein Complex Formed by the White Spot Syndrome Virus Structural Proteins
Outbreaks of white spot disease have had a large negative economic impact on cultured shrimp worldwide. However, the pathogenesis of the causative virus, WSSV (whit spot syndrome virus), is not yet well understood. WSSV is a large enveloped virus. The WSSV virion has three structural layers surrounding its core DNA: an outer envelope, a tegument and a nucleocapsid. In this study, we investigated the protein-protein interactions of the major WSSV structural proteins, including several envelope and tegument proteins that are known to be involved in the infection process.In the present report, we used coimmunoprecipitation and yeast two-hybrid assays to elucidate and/or confirm all the interactions that occur among the WSSV structural (envelope and tegument) proteins VP51A, VP19, VP24, VP26 and VP28. We found that VP51A interacted directly not only with VP26 but also with VP19 and VP24. VP51A, VP19 and VP24 were also shown to have an affinity for self-interaction. Chemical cross-linking assays showed that these three self-interacting proteins could occur as dimers.From our present results in conjunction with other previously established interactions we construct a 3D model in which VP24 acts as a core protein that directly associates with VP26, VP28, VP38A, VP51A and WSV010 to form a membrane-associated protein complex. VP19 and VP37 are attached to this complex via association with VP51A and VP28, respectively. Through the VP26-VP51C interaction this envelope complex is anchored to the nucleocapsid, which is made of layers of rings formed by VP664. A 3D model of the nucleocapsid and the surrounding outer membrane is presented
Polymers imprinted with three REG1B peptides for electrochemical determination of Regenerating Protein 1B, a urinary biomarker for pancreatic ductal adenocarcinoma
Three peptides (each containing 13–18 amino acids) were synthesized and used as templates for molecular imprinting and epitope recognition of the Regenerating Protein 1B (REG1B), which is one of the urinary biomarkers for pancreatic ductal adenocarcinoma (PDAC). Poly(ethylene-co-vinyl alcohol)s were employed as the host for molecular imprinting of the peptides. Following their preparation, the molecularly imprinted polymers (MIP) were examined by cyclic voltammetry. The electrochemical responses of a screen-printed gold substrate coated with the MIP were measured at a working voltage of 300 mV (vs. Ag/AgCl); the entire protein and the peptides gave similar responses at concentrations of <1.0 pg⋅mL−1, with detection limits as low as 0.1 pg⋅mL−1. Urine samples from healthy and PDAC patients were then analyzed by using this modified gold electrode, and the results are in agreement with data obtained with ELISA
Longitudinal double-spin asymmetry and cross section for inclusive jet production in polarized proton collisions at sqrt(s) = 200 GeV
We report a measurement of the longitudinal double-spin asymmetry A_LL and
the differential cross section for inclusive midrapidity jet production in
polarized proton collisions at sqrt(s)=200 GeV. The cross section data cover
transverse momenta 5 < pT < 50 GeV/c and agree with next-to-leading order
perturbative QCD evaluations. The A_LL data cover 5 < pT < 17 GeV/c and
disfavor at 98% C.L. maximal positive gluon polarization in the polarized
nucleon.Comment: 6 pages, 3 figures. Minor changes from review process in Phys. Rev.
Lett. Plain text tables of data in STAR publications may be found at
http://www.star.bnl.gov/central/publications
Identified baryon and meson distributions at large transverse momenta from Au+Au collisions at GeV
Transverse momentum spectra of , and up to 12 GeV/c
at mid-rapidity in centrality selected Au+Au collisions at GeV are presented. In central Au+Au collisions, both and
show significant suppression with respect to binary scaling at
4 GeV/c. Protons and anti-protons are less suppressed than
, in the range 1.5 6 GeV/c. The and
ratios show at most a weak dependence and no significant
centrality dependence. The ratios in central Au+Au collisions approach
the values in p+p and d+Au collisions at 5 GeV/c. The results at high
indicate that the partonic sources of , and have
similar energy loss when traversing the nuclear medium.Comment: 6 pages, 4 figure
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