Fast approximately timed simulation

International audienceIn this paper we present a technique for fast approximately timed simulation of software within a virtual prototyping framework. Our method performs a static analysis of the program control flow graph to construct annotations of the simulated program, combined with dynamic performance information. The static analysis estimates execution time based on a target architecture model. The delays introduced by instruction fetch and data cache misses are evaluated dynamically. At the end of each block, static and dynamic information are combined with branch target prediction to compute the total execution time of the blocks. As a result, we can provide approximate performance estimates with a high simulation speed that is still usable for software developers

PO-166 Neuromuscular Fatigue after maximal Concentric and Eccentric Contractions of Knee Extensor

Objective The aim of this study was to investigate after different maximal contractions concentric and eccentric would cause different neuromuscular fatigue of knee extensor.  Methods Ten healthy young men(21≤age≤24) who were not adapted by electrical stimulation were the subjects.The subjects were asked to arrive at the laboratory in three weeks at the same time of every week to avoid the effects of biological rhythms.Each subject performed three group maximal contractions on the ISOMED2000 isokinetic muscle tester according to the requirements.The subjects performed the same neuromuscular function test before and after exercise.The centripetal motion scheme:3*30,M1(knee flexion)-CON,M2(knee extension)-CON.angular velocity is 60 °,interval 30s in each group.Centrifugal motion scheme:3*30,M1(knee flexion)-ECC,M2(knee extension)-ECC.angular velocity is 60 °,interval 30s in each group.  Results The decrease rate of peak torque after concentric exercise was 55.93±13.20%, which was significantly higher than that after centrifugal exercise (20.06 ±11.06%, P < 0.01)The total work of the concentric movement was 8737.20±1543.43J, which was significantly smaller than that of the centrifugal exercise group (14312.20±2978.31J, P < 0. 01).The decline rate of MVC in concentric exercise was 24.89 ±10.54 and that in centrifugal exercise was 19.32±9.90,there was no significant difference between the two groups. Double Twitch induced a very significant decrease in PT-SSR RFD-SSN RHD-SS (P<0.01).There was no significant difference in VA decline rate.PAP decreased from 142.82±14.55% to 125.23±11.36 after concentric exercise, and after eccentric exercise PAP decreased from 141.1215.72% to 126.02 ±10.45.  Conclusions The neuromuscular fatigue caused by two kinds of exercise. Peripheral fatigue accounted for 39.19% after concentric exercise and 23.59% after centrifugal exercise,but there was little difference in the degree of central fatigue.All of them showed low frequency fatigue, and the low frequency fatigue after centrifugal exercise was more obvious. Key World:Neuromuscular fatigue; Electrical stimulation; High-frequency fatigue; Low-frequency fatigue; PAP

Dynamics Analysis and Chaos Identification of Compound Pendulum Jaw Crusher with Joint Clearance

A dynamic model of the working mechanism of a compound pendulum jaw crusher with clearance is established by the Lagrange multiplier method (LMD) based on the L-N contact force model and modified Coulomb friction force model. The correctness of the dynamic model is verified by MATLAB and Adams comparison simulation, and the best selection range of driving speed and clearance size is determined according to the laminating crushing theory (LCT). The effects of driving speed and clearance size on the shock and chaos phenomenon in the clearance mechanism are analyzed, as well as the vibration force applied to the foundation. The results show that, under the premise of meeting the requirements of crusher production capacity, increasing the driving speed and reducing the clearance size can weaken the shock and chaos phenomenon during the operation of the mechanism, improve the dynamic performance and enhance the operation stability, and the service life of foundation is prolonged with the stability of vibration force. Furthermore, the optimal combination of driving speed and clearance size is determined, which provides a theoretical basis for the optimization of the vibration force of the jaw crusher

Optimized Power Distribution Technology for Fast Frequency Response in Photovoltaic Power Stations

The fast frequency response (FFR) function in renewable energy source (RES)-based power stations has proved to be able to improve the frequency stability of power systems with high RES penetration significantly. However, most current FFR functions in photovoltaic (PV) power stations typically show power response deviations and unnecessary power loss issues that are caused by inadequate station power distribution strategies. This is particularly important in cases where the power must be increased when the system frequency shows a downward disturbance. This paper proposes a new distribution strategy for FFR in PV power stations and studies related distribution strategies, system structures, calculation algorithms, function execution effect, and active power regulation technology. The proposed approach uses a proportional distribution strategy based on an evaluation of the real-time potential maximum power capability values of the subarrays or generation regions, which are evaluated using a few reference inverters located in every subarray or region. Real-site deployments and tests have been completed in PV power stations to verify the effectiveness of this new distribution strategy, and the proposed FFR solution using this distribution strategy has demonstrated strong performance and potential for wider application scenarios

High HLA-F Expression Is a Poor Prognosis Factor in Patients with Nasopharyngeal Carcinoma

Background and Aims. In patients with nasopharyngeal carcinoma (NPC), local treatment failure and distant metastasis contribute largely to poor outcomes. The nasopharynx is an important lymphoid tissue, and NPC tumourigenesis and development are partly attributed to immune system disorders. Human leukocyte antigen F (HLA-F) has shown a close correlation with NPC in many genome-wide association studies (GWASs). However, clinical studies rarely explore the relationship of HLA-F expression with the clinical parameters and outcomes in patients with NPC. Methods. In this study, we used immunohistochemistry to evaluate HLA-F expression in 74 paraffin-embedded NPC tissue sections and then analysed the association between HLA-F expression and clinical parameters and outcomes. The plasma concentration of soluble HLA-F (sHLA-F) in NPC patients and normal controls was also detected, via enzyme-linked immunosorbent assay (ELISA). Results. Low, moderate, and high HLA-F expression levels were observed in 47.3% (35/74), 35.1% (26/74), and 17.6% (13/74), respectively, of the tissue samples. HLA-F expression showed a significant correlation with local recurrence (p=0.037) and distant metastasis (p=0.024) and was also an independent factor for local recurrence-free survival (LRFS; p=0.016) and distant metastasis-free survival (DMFS; p=0.004). Although the mean concentration of plasma sHLA-F in the NPC patients was higher than that in the normal controls (13.63 pg/ml vs. 10.06 pg/ml), no statistical significance was observed (p=0.118). Conclusions. Our study provides the first evidence that high HLA-F expression is associated with NPC local recurrence and distant metastasis and may be regarded as a poor prognostic factor for NPC patients. Additional studies using larger sample sizes may be necessary to determine whether sHLA-F is a feasible NPC diagnostic indicator