127 research outputs found

    WOMEN IN ENGINEERING: IDENTITY COMMUNICATION IN SOCIAL MEDIA

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    This thesis examines women engineers\u27 experience in social media with a focus on identity communication. Framing as a case study, this study attempts to explore women engineers\u27 online presence and how they utilize social media in their daily activities. Using the concept of intersectionality, this study addresses the differences of social media usage among women engineers in terms of the use of social media by professional organizations of women engineers and the use of individual women engineers. Thematic analysis was conducted to analyze the public available data from a Facebook page maintain by a well-known women engineers\u27 professional organization. Online survey was also conducted in order to capture individuals\u27 perceptions of using social media. Findings show, first, similar trends of using social media can be found among women engineers as the most popular social media accounts owned by women engineers are Facebook, LinkedIn and Twitter. Second, women engineers use social media mostly for information exchanging and maintaining pre-existing relationships with friends and family. Third, women engineers considered social media to be not effective platforms for professional communication and privacy issues are the major concerns of adopting social media. In summary, this study offers insights on women engineers\u27 online presence and suggests more effort is required in building online professional support networks for women engineers

    CAN MANUFACTURING OUTPUT SERVITIZATION REDUCE CARBON EMISSIONS?

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    Carbon emissions from manufacturing have been a growing global concern in recent years. The growth in manufacturing firms’ service output and its carbon emission reduction effect have received less attention, though. Using data from 2008-2020 for listed companies in China, this study empirically analyzed the effects of manufacturing output servitization on carbon intensity. The results revealed a significant negative relationship between them. Heterogeneity analysis finds that the carbon emission reduction effect of manufacturing servitization is strongest in (i) private and relatively small-scale firms and (ii) developed regions and capital-intensive industries. The mediating effect study shows that green TFP and revenue growth rate are the transmission channels for the environmental impact of manufacturing servitization. This study verifies that servitization is a feasible path to coordinate high-quality economic development with resource and environmental constraints from different perspectives to provide a reference for the realistic development of diverse economies

    Foreign Aid, Political Power and FDI: Do Aid-dependent Institutions Facilitate Investment in Africa?

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    In this article, we examine the nexus between foreign development assistance and the attraction of foreign direct investment (FDI) through a de facto political power, as an aid-seeking and likely aid-dependent group. We apply structural equation modelling to investigate the direct and indirect effect of aid on FDI via economic institutions for a sample of 42 African countries from 2002 to 2016. Our results corroborate a direct positive effect of aid and institutions on FDI as a productive financial source. However, an aid-dependent de facto political power does not improve the economic institutions, and within a broad institutional context, it may even worsen them, evidencing the indirect effect of reducing a country’s attractiveness for FDI. This study offers robust evidence under different specifications and variables of institutions in addition to several controls for political and strategic interests and economic conditions. We ultimately develop a model explaining why aid barely makes any contribution to institutional reforms. In countries that are heavily dependent on aid, the beneficiary group is discouraged from improving institutional qualities as the source of benefits would be discontinued

    Discrete time crystal in an open optomechanical system

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    The spontaneous breaking of time translation symmetry in periodically driven Floquet systems can lead to a discrete time crystal. Here we study the occurrence of such dynamical phase in a driven-dissipative optomechanical system with two membranes in the middle. We find that, under certian conditions, the system can be mapped to an open Dicke model and realizes a superradianttype phase transition. Furthermore, applying a suitable periodically modulated drive, the system dynamics exhibits a robust subharmonic oscillation persistent in the thermodynamic limit

    The Effect of Surface Treatments on Zirconia Bond Strength and Durability

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    To evaluate the effects of airborne particle abrasion (APA) combined with MDP-containing resin cement, a glass-ceramic spray deposition (GCSD) method on the shear bond strengths (SBSs) and durability of 3 mol% yttrium oxide-stabilized zirconia ceramic (3Y-TZP) compared with lithium disilicate glass ceramics (LDGC). 3Y-TZP disks were randomly treated as follows: for Group APA+MDP, 3Y-TZP was abrased using 50 µm Al2O3 particles under 0.1 Mpa and bonded with MDP-containing resin cement; for Group GCSD, 3Y-TZP was treated with the GCSD method, etched by 5% HF for 90 s, silanized and bonded with resin cement without MDP. Group LDGC was bonded as the Group GCSD. X-ray diffraction (XRD), attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR), X-ray photoelectron spectroscopy (XPS), scanning electron microscopy (SEM) and energy dispersive X-ray detector (EDX) were used to analyze the surface chemical and micro-morphological changes of the ceramics before bonding. The bonded ceramic specimens were randomly divided into subgroups, and the SBSs were determined before and after 10,000 thermocycling. The SBSs were analyzed with a one-way ANOVA analysis. Failure modes were determined with optical microscopy and SEM. The XRD, ATR-FTIR and XPS results identified the formation of lithium disilicate and zirconium silicate on 3Y-TZP after GCSD. The SEM micrographs revealed that 3Y-TZP surfaces were roughened by APA, while 3Y-TZP with GCSD and LDGC surfaces could be etched by HF to be porous. The APA treatment combined with MDP-containing resin cement produced the high immediate zirconia shear bond strengths (SBSs: 37.41 ± 13.51 Mpa) that was similar to the SBSs of the LDGC (34.87 ± 11.02 Mpa, p > 0.05), but, after thermocycling, the former dramatically decreased (24.00 ± 6.86 Mpa, maximum reduction by 35.85%) and the latter exhibited the highest SBSs (30.72 ± 7.97 Mpa, minimum reduction by 11.9%). The 3Y-TZP with GCSD treatment displayed the lower zirconia SBSs before thermocycling (27.03 ± 9.76 Mpa, p < 0.05), but it was similar to the 3Y-TZP treated with APA and MDP containing resin cement after thermocycling (21.84 ± 7.03 vs. 24.00 ± 6.86 Mpa, p > 0.05). The APA combined with MDP-containing resin cement could achieve the high immediate zirconia SBSs of those of the LDGC, but it decreased significantly after thermocycling. The GCSD technique could yield the immediate zirconia SBSs similar to those of LDGC before thermocycling, and long-term zirconia SBSs were similar to those of 3Y-TZP treated with APA followed by MDP-containing resin cement after thermocycling. Hence, the GCSD technique could enrich zirconia surface treatments and is an alternative to zirconia surface pretreatment for 3Y-TZP bond durability

    Generation of a recombinant rabies Flury LEP virus carrying an additional G gene creates an improved seed virus for inactivated vaccine production

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    The rabies Flury Low Egg Passage virus (LEP) has been widely used as a seed virus to generate inactive vaccine. Here, we established a reverse genetic system for LEP and generated a recombinant LEP virus (rLEP-G) that carries two identical G genes. This recombinant virus showed similar properties to those of LEP with respect to in vitro growth, neurotropism index, and virulence in mice. rLEP-G produced 4.3-fold more G protein than did LEP in BHK-21 cells. The inactivated vaccine generated from rLEP-G induced significantly higher virus neutralization titers in mice and dogs than those produced in response to LEP-derived vaccine. Our results suggest that rLEP-G is an improved seed virus candidate for inactivated rabies virus vaccine manufacture

    Macrophages Phenotype Regulated by IL-6 Are Associated with the Prognosis of Platinum-Resistant Serous Ovarian Cancer: Integrated Analysis of Clinical Trial and Omics

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    Background. The treatment of platinum-resistant recurrent ovarian cancer (PROC) is a clinical challenge and a hot topic. Tumor microenvironment (TME) as a key factor promoting ovarian cancer progression. Macrophage is a component of TME, and it has been reported that macrophage phenotype is related to the development of PROC. However, the mechanism underlying macrophage polarization and whether macrophage phenotype can be used as a prognostic indicator of PROC remains unclear. Methods. We used ESTIMATE to calculate the number of immune and stromal components in high-grade serous ovarian cancer (HGSOC) cases from The Cancer Genome Atlas database. The differential expression genes (DEGs) were analyzed via protein–protein interaction network, Kyoto Encyclopedia of Genes and Genomes (KEGG) and gene ontology (GO) analysis to reveal major pathways of DEGs. CD80 was selected for survival analysis. IL-6 was selected for gene set enrichment analysis (GSEA). A subsequent cohort study was performed to confirm the correlation of IL-6 expression with macrophage phenotype in peripheral blood and to explore the clinical utility of macrophage phenotype for the prognosis of PROC patients. Results. A total of 993 intersecting genes were identified as candidates for further survival analysis. Further analysis revealed that CD80 expression was positively correlated with the survival of HGSOC patients. The results of GO and KEGG analysis suggested that macrophage polarization could be regulated via chemokine pathway and cytokine–cytokine receptor interaction. GSEA showed that the genes were mainly enriched in IL-6-STAT-3. Correlation analysis for the proportion of tumor infiltration macrophages revealed that M2 was correlated with IL-6. The results of a cohort study demonstrated that the regulation of macrophage phenotype by IL-6 is bidirectional. The high M1% was a protective factor for progression-free survival. Conclusion. Thus, the macrophage phenotype is a prognostic indicator in PROC patients, possibly via a hyperactive IL-6-related pathway, providing an additional clue for the therapeutic intervention of PROC
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