1,009 research outputs found

    Thoughts from the Editors

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    An introduction is presented in which the editor discusses various reports within the issue on topics including teaching and learning language arts from preschool to middle school age, the several children\u27s literature, and interviews with several scholars, authors, and researchers

    Geometrical Relationships Specifying the Phyllotactic Pattern of Aquatic Plants

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    Aquatic plants provide an opportunity to characterize the geometrical relationships of leaf patterning. A new polar-coordinate model was used to correlate meristem shape and leaf arrangement in aquatic plants. In aquatic plants, the primary geometrical relationship specifying spiral vs. whorled phyllotaxis is primordial position: primordia arising on the apical dome (as defined by displacement angles θ ≤ 90° during maximal phase) are often positioned in spiral patterns, whereas primordia arising on the subtending axis (as defined by displacement angles of θ ≥ 90° during maximal phase) are arranged in whorled patterns. A secondary geometrical relationship shows an inverse correlation between the primordial size : available space ratio and the magnitude of the Fibonacci numbers in spiral phyllotaxis or the number of leaves per whorl in whorled phyllotaxis. This geometrical analysis provides the morphological context for interpreting phyllotaxis mutants and for constructing realistic models phyllotactic patterns

    Neurotoxicity and aggressiveness triggered by low-level lead in children: a review

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    Lead-induced neurotoxicity acquired by low-level long-term exposure has special relevance for children. A plethora of recent reports has demonstrated a direct link between low-level lead exposure and deficits in the neurobehavioral-cognitive performance manifested from childhood through adolescence. In many studies, aggressiveness and delinquency have also been suggested as symptoms of lead poisoning. Several environmental, occupational and domestic sources of contaminant lead and consequent health risks are largely identified and understood, but the occurrences of lead poisoning remain numerous. There is an urgent need for public health policies to prevent lead poisoning so as to reduce individual and societal damages and losses. In this paper we describe unsuspected sources of contaminant lead, discuss the economic losses and urban violence possibly associated with lead contamination and review the molecular basis of lead-induced neurotoxicity, emphasizing its effects on the social behavior, delinquency and IQ of children and adolescent

    Putting health workers at the centre of health system investments in COVID-19 and beyond

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    The COVID-19 pandemic highlights the implications of chronic underinvestment in health workforce development, particularly in resource-constrained health systems. Inadequate health workforce diversity, insufficient training and remuneration, and limited support and protection reduce health system capacity to equitably maintain health service delivery while meeting urgent health emergency demands. Applying the Health Worker Life Cycle Approach provides a useful conceptual framework that adapts a health labour market approach to outline key areas and recommendations for health workforce investment-building, managing and optimising-to systematically meet the needs of health workers and the systems they support. It also emphasises the importance of protecting the workforce as a cross-cutting investment, which is especially important in a health crisis like COVID-19. While the global pandemic has spurred intermittent health workforce investments required to immediately respond to COVID-19, applying this 'lifecycle approach' to guide policy implementation and financing interventions is critical to centering health workers as stewards of health systems, thus strengthening resilience to public health threats, sustainably responding to community needs and providing more equitable, patient-centred care

    Association of dental enamel lead levels with risk factors for environmental exposure

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    OBJECTIVE: To analyze household risk factors associated with high lead levels in surface dental enamel. METHODS: A cross-sectional study was conducted with 160 Brazilian adolescents aged 14-18 years living in poor neighborhoods in the city of Bauru, southeastern Brazil, from August to December 2008. Body lead concentrations were assessed in surface dental enamel acid-etch microbiopsies. Dental enamel lead levels were measured by graphite furnace atomic absorption spectrometry and phosphorus levels were measured by inductively coupled plasma optical emission spectrometry. The parents answered a questionnaire about their children's potential early (05 years old) exposure to well-known lead sources. Logistic regression was used to identify associations between dental enamel lead levels and each environmental risk factor studied. Social and familial covariables were included in the models. RESULTS: The results suggest that the adolescents studied were exposed to lead sources during their first years of life. Risk factors associated with high dental enamel lead levels were living in or close to a contaminated area (OR = 4.49; 95% CI: 1.69;11.97); and member of the household worked in the manufacturing of paints, paint pigments, ceramics or batteries (OR = 3.43; 95% CI: 1.31;9.00). Home-based use of lead-glazed ceramics, low-quality pirated toys, anticorrosive paint on gates and/or sale of used car batteries (OR = 1.31; 95% CI: 0.56;3.03) and smoking (OR = 1.66; 95% CI: 0.52;5.28) were not found to be associated with high dental enamel lead levels. CONCLUSIONS: Surface dental enamel can be used as a marker of past environmental exposure to lead and lead concentrations detected are associated to well-known sources of lead contamination.OBJETIVO: Analizar factores de riesgo en el ambiente domiciliar asociados con altos niveles de plomo en el esmalte dental superficial. MÉTODOS: Se realizó estudio transversal con 160 adolescentes brasileros (14 a 18 años), residentes en urbanizaciones pobres del municipio de Bauru, SP, de agosto a diciembre de 2008. La concentración de plomo en el esmalte dental fue evaluada por micro biopsias ácidas del esmalte dental superficial, cuantificada por espectrometría de absorción atómica con horno de grafito y la concentración de fósforo fue medida por espectrometría de absorción óptica con plasma inductivamente acoplado. Los padres de los adolescentes respondieron a cuestionario sobre posible exposición previa (5 primeros años de vida del adolescente) al plomo producto de fuentes de contaminación bien conocidas. Se usó regresión logística para identificar asociaciones entre concentración de plomo en el esmalte y factores de riesgo ambientales. Covariables familiares y sociales fueron incluidas en los modelos. RESULTADOS: Los resultados sugieren que los jóvenes evaluados fueron expuestos a fuentes de plomo durante sus primeros años de vida. Los factores de riesgo asociados con el resultado fueron residir en área contaminada por plomo o en sus proximidades (OR=4,49; IC 95%: 1,69;11,97) y haber convivido, en el mismo domicilio, con persona que trabajaba en fábrica de tintas, pigmentos, cerámicas o baterías (OR= 3,43; IC 95%: 1,31;9,00). Haber usado, en casa, cerámica vitrificada, juegos de baja calidad o piratas, haber aplicado zircón en portones de hierro sin cobertura esmaltada o almacenar baterías de carro usadas en la residencia (OR= 1,31; IC 95%: 0,56-3,03) y hábito de fumar no fueron asociados con altas concentraciones de plomo en el esmalte dental (OR=1,66; IC 95%: 0,52;5,28). CONCLUSIONES: El esmalte dental superficial puede ser utilizado como marcador de exposición ambiental pasada al plomo y las concentraciones encontradas de dicho metal están relacionadas con fuentes bien conocidas de contaminación por plomo.OBJETIVO: Analisar fatores de risco no ambiente domiciliar associados com altos níveis de chumbo no esmalte dentário superficial. MÉTODOS: Estudo transversal conduzido com 160 adolescentes brasileiros (14 a 18 anos), residentes em bairros pobres do município de Bauru, SP, de agosto a dezembro de 2008. A concentração de chumbo no esmalte dentário foi avaliada por microbiópsias ácidas do esmalte dentário superficial, quantificada por espectrometria de absorção atômica com forno de grafite e a concentração de fósforo foi medida por espectrometria de absorção óptica com plasma indutivamente acoplado. Os pais dos adolescentes responderam a questionário sobre possível exposição prévia (cinco primeiros anos de vida do adolescente) a chumbo decorrente de fontes de contaminação bem conhecidas. Usou-se regressão logística para identificar associações entre concentração de chumbo no esmalte e fatores de risco ambientais. Covariáveis familiares e sociais foram incluídas nos modelos. RESULTADOS: Os resultados sugerem que os jovens avaliados foram expostos a fontes de chumbo durante seus primeiros anos de vida. Os fatores de risco associados com o desfecho foram residir em área contaminada por chumbo ou nas suas proximidades (OR = 4,49; IC 95%: 1,69;11,97) e ter convivido, no mesmo domicílio, com pessoa que trabalhava em fábrica de tintas, pigmentos, cerâmicas ou baterias (OR = 3,43; IC 95%: 1,31;9,00). Ter usado, em casa, cerâmica vitrificada, brinquedos de baixa qualidade ou piratas, ter aplicado zarcão em portões de ferro sem cobertura esmaltada ou armazenar baterias de carro usadas na residência (OR = 1,31; IC 95%: 0,56;3,03) e hábito de fumar não foram associados com altas concentrações de chumbo no esmalte dentário (OR = 1,66; IC 95%: 0,52;5,28). CONCLUSÕES: O esmalte dentário superficial pode ser utilizado como marcador de exposição ambiental passada ao chumbo e as concentrações encontradas desse metal estão ligadas a fontes bem conhecidas de contaminação por chumbo

    Translating Provider and Staff Engagement Results to Actionable Planning and Outcomes

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    Staff and provider engagement leads to better quality and experience of care and less turnover and burnout. In this program, we describe an approach to better understand underlying factors that lead to low staff and provider engagement and address such factors by creating actionable plans that drive improved engagement measures. Focus groups were conducted with staff, advance practice providers, and faculty to better understand low scored areas in an annual third-party engagement survey. Focus group results were analyzed, and thematic action plans were then developed by a leadership team. These plans and the status of addressing the identified issues were published and disseminated back to all staff and providers using a stoplight report. The leadership team met every 2 to 4 weeks until all issues were addressed and communicated back to the department. The subsequent year\u27s engagement scores statistically increased across all engagement score domains for both staff and faculty. We conclude that using a qualitative approach to understanding low-scored engagement domains will allow a deeper and authentic understanding of the root factors that drive low engagement scores. This approach allows teams to develop responsive action plans, resulting in higher engagement scores, which will eventually lead to better service and care to patients

    Mortality after the First Diagnosis of Schizophrenia-Spectrum Disorders: A Population-based Retrospective Cohort Study

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    There is emerging evidence of high mortality rates after the first diagnosis of psychotic disorder. The objective of this study was to estimate the standardized mortality ratio (SMR) in a population-based cohort of individuals with a first diagnosis of schizophrenia-spectrum psychotic disorder (SSD). The cohort included a population-based sample of individuals with a first diagnosis of SSD based on the first diagnosis occurring during hospitalization or in an outpatient setting between 2007 and 2010 in Ontario, Canada. All patients were followed for 5 years after the first diagnosis. The primary outcome was SMR, including all-cause, suicide-related, accidental, and other causes. Between 2007 and 2010, there were 2382 patients in the hospitalization cohort and 11 003 patients in the outpatient cohort. Over the 5-year observation period, 97 (4.1%) of the hospitalization cohort and 292 (2.7%) of the outpatient cohort died, resulting in an SMR of 13.6 and 9.1, respectively. In both cohorts, suicide was the most common cause of death. Approximately 1 in 25 patients with a first diagnosis of SSD during hospitalization, and 1 in 40 patients with a first diagnosis of SSD in an outpatient setting, died within 5 years of first diagnosis in Ontario, Canada. This mortality rate is between 9 and 13 times higher than would be expected in the age-matched general population. Based on these data, timely access to services should be a public health priority to reduce mortality following a first diagnosis of an SSD
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