The International Linear Collider beam dumps

The ILC beam dumps are a key part of the accelerator design. At Snowmass 2005, the current status of the beam dump designs were reviewed, and the options for the overall dump layout considered. This paper describes the available dump options for the baseline and the alternatives and considers issues for the dumps that require resolution.Comment: Prepared for 2005 International Linear Collider Physics and Detector Workshop and 2nd ILC Accelerator Workshop, Snowmass, Colorado, 14-27 Aug 200

Continuous Lyman-alpha generation by four-wave mixing in mercury for laser-cooling of antihydrogen

Cooling antihydrogen atoms is important for future experiments both to test the fundamental CPT symmetry by high-resolution laser spectroscopy and also to measure the gravitational acceleration of antimatter. Laser-cooling of antihydrogen can be done on the strong 1S-2P transition at the wavelength of Lyman-alpha (121.6nm). A continuous-wave laser at the Lyman-alpha wavelength based on solid-state fundamental lasers is described. By using a two-photon and a near one photon resonance a scan across the whole phasematching curve of the four-wave mixing process is possible. Furthermore the influence of the beam profile of one fundamental beam on the four-wave mixing process is studied.Comment: 4 pages, 4 figure

Laser cooling of new atomic and molecular species with ultrafast pulses

We propose a new laser cooling method for atomic species whose level structure makes traditional laser cooling difficult. For instance, laser cooling of hydrogen requires single-frequency vacuum-ultraviolet light, while multielectron atoms need single-frequency light at many widely separated frequencies. These restrictions can be eased by laser cooling on two-photon transitions with ultrafast pulse trains. Laser cooling of hydrogen, antihydrogen, and many other species appears feasible, and extension of the technique to molecules may be possible.Comment: revision of quant-ph/0306099, submitted to PR

Time-Domain Measurement of Broadband Coherent Cherenkov Radiation

We report on further analysis of coherent microwave Cherenkov impulses emitted via the Askaryan mechanism from high-energy electromagnetic showers produced at the Stanford Linear Accelerator Center (SLAC). In this report, the time-domain based analysis of the measurements made with a broadband (nominally 1-18 GHz) log periodic dipole array antenna is described. The theory of a transmit-receive antenna system based on time-dependent effective height operator is summarized and applied to fully characterize the measurement antenna system and to reconstruct the electric field induced via the Askaryan process. The observed radiation intensity and phase as functions of frequency were found to agree with expectations from 0.75-11.5 GHz within experimental errors on the normalized electric field magnitude and the relative phase; 0.039 microV/MHz/TeV and 17 deg, respectively. This is the first time this agreement has been observed over such a broad bandwidth, and the first measurement of the relative phase variation of an Askaryan pulse. The importance of validation of the Askaryan mechanism is significant since it is viewed as the most promising way to detect cosmogenic neutrino fluxes at E > 10^15 eV.Comment: 10 pages, 9 figures, accepted by Phys. Rev.

Anti-malarial ozonides OZ439 and OZ609 tested at clinically relevant compound exposure parameters in a novel ring-stage survival assay

BACKGROUND: Drug efficacy against kelch 13 mutant malaria parasites can be determined in vitro with the ring-stage survival assay (RSA). The conventional assay protocol reflects the exposure profile of dihydroartemisinin. METHODS: Taking into account that other anti-malarial peroxides, such as the synthetic ozonides OZ439 (artefenomel) and OZ609, have different pharmacokinetics, the RSA was adjusted to the concentration-time profile of these ozonides in humans and a novel, semi-automated readout was introduced. RESULTS: When tested at clinically relevant parameters, it was shown that OZ439 and OZ609 are active against the Plasmodium falciparum clinical isolate Cam3.I(R539T). CONCLUSION: If the in vitro RSA does indeed predict the potency of compounds against parasites with increased tolerance to artemisinin and its derivatives, then the herein presented data suggest that following drug-pulses of at least 48 h, OZ439 and OZ609 will be highly potent against kelch 13 mutant isolates, such as P. falciparum Cam3.I(R539T)

Characterization of elemental ratios and oxidative ratio of horticultural peat

peer-reviewedPeatlands occupy 20% of the land area of Ireland and store over half of soil carbon stocks. Over 80% of these peatlands have been disturbed by human activity such as drainage for peat extraction, afforestation and agriculture. In this study, peat samples were collected from 12 horticultural peat extraction sites in the Irish midlands. The carbon (C), nitrogen (N), hydrogen, and sulphur content were determined, and from these the carbon oxidation state (Cox) and oxidative ratio (OR) were calculated. The carbon oxidation ratio reflects organic matter synthesis and degradation, and is thus an important parameter in understanding terrestrial carbon cycling, whilst OR represents the molar ratio of oxygen (O2) and carbon dioxide (CO2) fluxes associated with net ecosystem exchange. Elemental concentrations and ratios were typical for Irish horticultural peat (e.g. carbon concentrations 54 – 57%), though showed site to site variability. Cox and OR values varied between -0.22 and -0.11, and 1.04 and 1.07 respectively and were comparable to United Kingdom peat soils. All values for OR were lower than 1.1, the value commonly used in global CO2 partitioning studies. Further research should investigate OR values in peatland which has not been studied to date. Across all sites, measures of increased decomposition (i.e. C/N ratios) significantly correlated with increasing OR reflecting more reduced organic matter. This study provides data in temperate peat soils that increases the coverage of Cox and OR values and will inform global CO2 partitioning studies

Stress condensation in crushed elastic manifolds

We discuss an M-dimensional phantom elastic manifold of linear size L crushed into a small sphere of radius R << L in N-dimensional space. We investigate the low elastic energy states of 2-sheets (M=2) and 3-sheets (M=3) using analytic methods and lattice simulations. When N \geq 2M the curvature energy is uniformly distributed in the sheet and the strain energy is negligible. But when N=M+1 and M>1, both energies appear to be condensed into a network of narrow M-1 dimensional ridges. The ridges appear straight over distances comparable to the confining radius R.Comment: 4 pages, RevTeX + epsf, 4 figures, Submitted to Phys. Rev. Let

High-energy photoemission on Fe3O4: Small polaron physics and the Verwey transition

We have studied the electronic structure and charge ordering (Verwey) transition of magnetite (Fe3O4) by soft x-ray photoemission. Due to the enhanced probing depth and the use of different surface preparations we are able to distinguish surface and volume effects in the spectra. The pseudogap behavior of the intrinsic spectra and its temperature dependence give evidence for the existence of strongly bound small polarons consistent with both dc and optical conductivity. Together with other recent structural and theoretical results our findings support a picture in which the Verwey transition contains elements of a cooperative Jahn-Teller effect, stabilized by local Coulomb interaction