395 research outputs found
Actual and Ideal Shared Decision-making Perceptions of Elementary School Teachers in East Tennessee
The problem of this study was to determine if differences existed between teachers\u27 perceptions of the actual and ideal level of involvement in decision making in elementary schools. It represents one part of a comprehensive research project conducted simultaneously with two other researchers. The parallel studies examined principals\u27 and parents\u27 involvement in school decision making. The study was conducted during the 1993-94 school year in Tennessee. Significant differences were found between teachers\u27 perception of the actual and ideal levels of involvement in decisions concerning the budgetary process, personnel matters, and curriculum decisions. Teachers also indicated that principals and parents should have significantly more involvement in these three areas. It was concluded that teachers want teachers, principals, and parents to have significantly more involvement in decisions. The parallel studies also indicated strong opinions concerning the amount of involvement that principals and parents should have in decision making
Fluency Patterns of Adult Females with Focal Epilepsy
The purpose of this study was to determine the fluency patterns in female adults diagnosed with focal epilepsy. This study used a two-group parallel quasi-experimental design. Standard scores from the Montreal Cognitive Assessment (MoCA) were collected in addition to a two-hundred-word narrative production and a semantic verbal fluency task from each of the nineteen adult female participants between 18 and 35 years of age. Six participants with focal epilepsy and thirteen non-epileptic peers were included. Narratives were recorded and analyzed for variations in speech fluency, while the MoCA and semantic verbal fluency task were used to analyze cognition and verbal fluency. The results indicated a significant difference in phonemic verbal fluency and cognition between those with focal epilepsy and the control group. No significant differences were observed for speech fluency or semantic verbal fluency between the two groups although trends were in the hypothesized directions. Additionally, family history of epilepsy and suspected diagnoses of TLE or FLE did not appear to affect speech, language, or cognitive outcomes
‘What’s in a Name?’: Mislabelling, misidentification, and the US government’s failure to protect human trafficking survivors in the Central American refugee crisis
This article explores how competing and overlapping legal classifications such as ‘victim of trafficking’, ‘smuggled migrant’, ‘illegal alien’, and ‘refugee’ play out in the United States (US) immigration system. In particular, it focuses on the repeated failure of US authorities to identify and protect survivors of human trafficking who were victimised by the smugglers they voluntarily employed in fleeing their home countries—a scenario that is becoming increasingly common in the midst of the Central American refugee crisis. The article draws upon the authors’ experience providing direct legal representation to Central American migrants in the US to discuss how misassumptions about this population, a misunderstanding of the relevant legal terminology, and the US government’s focus on border security negatively impact the conduct of law enforcement agencies and immigration adjudicators. Due in large part to the US government’s increased restrictions on, and criminalisation of, many forms of migration, survivors of human trafficking who are victimised by smugglers often find themselves classified as ‘illegal aliens’ or ‘criminal aliens’, and their legitimate claims for protection are frequently dismissed for the irrelevant fact that they initially consented to be smuggled. Such mistreatment and misidentification fail to hold perpetrators accountable, and to offer assistance to populations that the US government has pledged to defend
Attrition in School Rowing in New Zealand: A Qualitative Descriptive Study
It is widely acknowledged that involvement in sport has positive physical and psychosocial benefits for adolescents. However, concerns have been expressed, both in New Zealand and internationally, about the relatively high attrition rates in youth sport. This qualitative study captured the experiences of eight (five male, three female) adolescents who were no longer participating in high school rowing programs in New Zealand. Data were gathered through semi-structured interviews, and we conducted an inductive thematic analysis. A secondary analysis was then conducted using a self-determination and basic psychological needs framework that placed specific emphasis on need satisfaction and need thwarting. Key findings from this study suggest that participants’ experiences of rowing were initially positive but were subsequently influenced by dissatisfaction and thwarting of basic psychological needs. The findings confirm the significance of coaches and parents providing an environment that supports young athletes’ needs for relatedness. Concerns are also raised about the potentially damaging effects of weight-restricted sport for adolescents. By drawing upon athlete voice, it is hoped that the findings of this study can inform coach education and result in the development of more athlete-supportive rowing programs for adolescent athletes
Rebecca Fillyaw MS Thesis Data for Publication in the Journal Sustainability
By combatting erosion and increasing habitat, mangrove living shorelines are an effective alternative to hard-armoring in tropical and subtropical areas. An experimental red mangrove living shoreline was deployed within Mosquito Lagoon, Florida, using a factorial design to test the impact of mangrove age, breakwater presence, and mangrove placement on mangrove survival within the first year of deployment. Mixed mangrove age treatments were included to identify if seedling (11-month-old) survival could be enhanced by the presence of transitional (23-month-old) and adult (35 to 47-month-old) mangroves. Environmental factors were monitored to detect possible causes of mangrove mortalities. Approximately half (50.6%) of mangroves died, and of those, 90.7% occurred within the annual high-water season, and 88.9% showed signs of flooding stress. Planting seedlings haphazardly among older mangroves did not attenuate enough wave energy to significantly increase seedling survival. Breakwaters alleviated stress through the reduction of water velocity and wave height, increasing the odds of survival by 197% and 437% when mangroves were planted in the landward and seaward rows, respectively. Compared to seedlings, deployment of adult mangroves increased survival odds by 1,087%. Collectively, our results indicate that sites with a high-water season should utilize a breakwater structure and mangroves with a woody stem
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Mfsd14a disruption causes globozoospermia
The Mfsd14a gene, previously called Hiat1, encodes a transmembrane protein of unknown function with homology to the solute carrier protein family. To study the function of the MFSD14A protein, mutant mice (Mus musculus, strain 129S6Sv/Ev) were generated with the Mfsd14a gene disrupted with a LacZ reporter gene. Homozygous mutant mice are viable and healthy, but males are sterile due to a 100-fold reduction in the number of spermatozoa in the vas deferens. Male mice have adequate levels of testosterone and show normal copulatory behaviour. The few spermatozoa that are formed show rounded head defects similar to those found in humans with globozoospermia. Spermatogenesis proceeds normally up to the round spermatid stage, but the subsequent structural changes associated with spermiogenesis are severely disrupted with failure of acrosome formation, sperm head condensation and mitochondrial localization to the mid-piece of the sperm. Staining for β-galactosidase activity as a surrogate for Mfsd14a expression indicates expression in Sertoli cells, suggesting that MFSD14A may transport a solute from the bloodstream that is required for spermiogenesis.This work was funded by a Ford Physiology Fund Endowment (WHC).This is the author accepted manuscript. The final version is available from Bioscientifica via http://dx.doi.org/10.1530/REP-15-055
Inequalities in receipt of mental and physical healthcare in people with dementia in the UK
Background: UK Dementia Strategies prioritise fair access to mental and physical healthcare. We investigated whether there are inequalities by deprivation or gender in healthcare received by people with dementia, and compared healthcare received by people with and without dementia. Methods: we investigated primary care records of 68,061 community dwelling dementia patients and 259,337 people without dementia (2002-13). We tested hypotheses that people with dementia from more deprived areas, and who are women receive more psychotropic medication, fewer surgery consultations, are less likely to receive annual blood pressure, weight monitoring and an annual review, compared with those from less deprived areas and men. Results: only half of people with dementia received a documented annual review. Deprivation was not associated with healthcare received. Compared to men with dementia, women with dementia had lower rates of surgery consultations (adjusted incidence rate ratio (IRR) 0.90, 95% CI 0.90-0.91), of annual blood pressure monitoring (adjusted IRR 0.96, 95% CI 0.95-0.97) and of annual weight monitoring (adjusted IRR 0.91, 95% CI 0.90-0.93). Men with dementia were less likely to be taking psychotropic medication than women with dementia. People with dementia had fewer surgery consultations and were less likely to have their weight and blood pressure monitored at least annually, compared to the non-dementia group. Conclusions: people with dementia, in particular women, appear to receive less primary healthcare, but take more psychotropic medication that may negatively impact their physical health. Reducing these inequalities and improving access of people with dementia to preventative healthcare could improve the health of people with dementia.</p
Interactivity:the missing link between virtual reality technology and drug discovery pipelines
The potential of virtual reality (VR) to contribute to drug design and
development has been recognised for many years. Hardware and software
developments now mean that this potential is beginning to be realised, and VR
methods are being actively used in this sphere. A recent advance is to use VR
not only to visualise and interact with molecular structures, but also to
interact with molecular dynamics simulations of 'on the fly' (interactive
molecular dynamics in VR, IMD-VR), which is useful not only for flexible
docking but also to examine binding processes and conformational changes.
iMD-VR has been shown to be useful for creating complexes of ligands bound to
target proteins, e.g., recently applied to peptide inhibitors of the SARS-CoV-2
main protease. In this review, we use the term 'interactive VR' to refer to
software where interactivity is an inherent part of the user VR experience
e.g., in making structural modifications or interacting with a physically
rigorous molecular dynamics (MD) simulation, as opposed to simply using VR
controllers to rotate and translate the molecule for enhanced visualisation.
Here, we describe these methods and their application to problems relevant to
drug discovery, highlighting the possibilities that they offer in this arena.
We suggest that the ease of viewing and manipulating molecular structures and
dynamics, and the ability to modify structures on the fly (e.g., adding or
deleting atoms) makes modern interactive VR a valuable tool to add to the
armoury of drug development methods.Comment: 19 pages, 3 figure
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