28,969 research outputs found
A Forward Branching Phase Space Generator for Hadron colliders
In this paper we develop a projective phase space generator appropriate for
hadron collider geometry. The generator integrates over bremsstrahlung events
which project back to a single, fixed Born event. The projection is dictated by
the experimental jet algorithm allowing for the forward branching phase space
generator to integrate out the jet masses and initial state radiation. When
integrating over the virtual and bremsstrahlung amplitudes this results in a
single K-factor, assigning an event probability to each Born event. This
K-factor is calculable as a perturbative expansion in the strong coupling
constant. One can build observables from the Born kinematics, giving identical
results to tradi- tional observables as long as the observable does not depend
on the infrared sensitive jet mass or initial state radiation.Comment: 16 pages, 10 figure
Sets of Priors Reflecting Prior-Data Conflict and Agreement
In Bayesian statistics, the choice of prior distribution is often debatable,
especially if prior knowledge is limited or data are scarce. In imprecise
probability, sets of priors are used to accurately model and reflect prior
knowledge. This has the advantage that prior-data conflict sensitivity can be
modelled: Ranges of posterior inferences should be larger when prior and data
are in conflict. We propose a new method for generating prior sets which, in
addition to prior-data conflict sensitivity, allows to reflect strong
prior-data agreement by decreased posterior imprecision.Comment: 12 pages, 6 figures, In: Paulo Joao Carvalho et al. (eds.), IPMU
2016: Proceedings of the 16th International Conference on Information
Processing and Management of Uncertainty in Knowledge-Based Systems,
Eindhoven, The Netherland
The small molecule ISRIB reverses the effects of eIF2α phosphorylation on translation and stress granule assembly.
Previously, we identified ISRIB as a potent inhibitor of the integrated stress response (ISR) and showed that ISRIB makes cells resistant to the effects of eIF2α phosphorylation and enhances long-term memory in rodents (Sidrauski et al., 2013). Here, we show by genome-wide in vivo ribosome profiling that translation of a restricted subset of mRNAs is induced upon ISR activation. ISRIB substantially reversed the translational effects elicited by phosphorylation of eIF2α and induced no major changes in translation or mRNA levels in unstressed cells. eIF2α phosphorylation-induced stress granule (SG) formation was blocked by ISRIB. Strikingly, ISRIB addition to stressed cells with pre-formed SGs induced their rapid disassembly, liberating mRNAs into the actively translating pool. Restoration of mRNA translation and modulation of SG dynamics may be an effective treatment of neurodegenerative diseases characterized by eIF2α phosphorylation, SG formation, and cognitive loss
Pseudogap at hot spots in the two-dimensional Hubbard model at weak coupling
We analyze the interaction-induced renormalization of single-particle
excitations in the two-dimensional Hubbard model at weak coupling using the
Wick-ordered version of the functional renormalization group. The self energy
is computed for real frequencies by integrating a flow equation with
renormalized two-particle interactions. In the vicinity of hot spots, that is
points where the Fermi surface intersects the umklapp surface, self energy
effects beyond the usual quasi-particle renormalizations and damping occur near
instabilities of the normal, metallic phase. Strongly enhanced renormalized
interactions between particles at different hot spots generate a pronounced
low-energy peak in the imaginary part of the self energy, leading to a
pseudogap-like double-peak structure in the spectral function for
single-particle excitations.Comment: 14 pages, 7 figure
Revisiting the Parallax of the Isolated Neutron Star RX J185635-3754 Using HST/ACS Imaging
We have redetermined the parallax and proper motion of the nearby isolated
neutron star RX~J185635-3754. We used eight observations with the high
resolution camera of the HST/ACS taken from 2002 through 2004. We performed the
astrometric fitting using five independent methods, all of which yielded
consistent results. The mean estimate of the distance is 123 (+11, -15) pc (1
sigma), in good agreement with our earlier published determination
Pomeranchuk effect and spin-gradient cooling of Bose-Bose mixtures in an optical lattice
We theoretically investigate finite-temperature thermodynamics and
demagnetization cooling of two-component Bose-Bose mixtures in a cubic optical
lattice, by using bosonic dynamical mean field theory (BDMFT). We calculate the
finite-temperature phase diagram, and remarkably find that the system can be
heated from the superfluid into the Mott insulator at low temperature,
analogous to the Pomeranchuk effect in 3He. This provides a promising many-body
cooling technique. We examine the entropy distribution in the trapped system
and discuss its dependence on temperature and an applied magnetic field
gradient. Our numerical simulations quantitatively validate the spin-gradient
demagnetization cooling scheme proposed in recent experiments.Comment: 9 pages, 8 figure
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