2,445 research outputs found

    Eminent Domain: A Legal and Economic Critique

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    Frontiers in Biocatalysis

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    Biocarbon from Pruning and Gardening Residues on The Santander University Campus, Using a Pirolisis System with Minimal Gas Emission

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    A pilot – level system of the termal pirolisis process was developed to obtain biocarbon with minimal emission of polluting gases, from the solid waste generated in the pruning gases, from the solid waste generated in the pruning and gardening of the university campus of the University of Santander in Bucaramanga Colombia. The pilot – level system has a processing capacity of 50 kilograms of prunning and garden waste, and the operating variables ser 500ªC of temperatura and 120 minutes of processing. The prunnig and gardenning samples were divided into two. The first simple consisted of Woody-type residues (pruningn), the second simple consisted of grass and leat litter remains. The biocarbons obtaneid were characerized physicochemically, by close analysis and last chemical analysis (CHN). For its part, the morphology of the biocarbons and the microchemical anlysis of the ash particles that they possessed was carried out by means of scanning electron microscopy coupled with chemical microanalysis by means of X-ray dispersive energy spectroscopy. The biocarbon obtained can be used as soil additions to increase the forests that surrond the University campus

    Toll-like receptor 4 deficiency facilitates α-synuclein propagation and neurodegeneration in a mouse model of prodromal Parkinson's disease

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    The evidence linking innate immunity mechanisms and neurodegenerative diseases is growing, but the specific mechanisms are incompletely understood. Experimental data suggest that microglial TLR4 mediates the uptake and clearance of α-synuclein also termed synucleinophagy. The accumulation of misfolded α-synuclein throughout the brain is central to Parkinson's disease (PD). The distribution and progression of the pathology is often attributed to the propagation of α-synuclein. Here, we apply a classical α-synuclein propagation model of prodromal PD in wild type and TLR4 deficient mice to study the role of TLR4 in the progression of the disease. Our data suggest that TLR4 deficiency facilitates the α-synuclein seed spreading associated with reduced lysosomal activity of microglia. Three months after seed inoculation, more pronounced proteinase K-resistant α-synuclein inclusion pathology is observed in mice with TLR4 deficiency. The facilitated propagation of α-synuclein is associated with early loss of dopamine transporter (DAT) signal in the striatum and loss of dopaminergic neurons in substantia nigra pars compacta of TLR4 deficient mice. These new results support TLR4 signaling as a putative target for disease modification to slow the progression of PD and related disorders

    TeO2-ZnO-La2O3 glass composition for mid infrared wavelengths generation and transmission in optical fibers

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    Numerous applications in the Mid InfraRed (Mid IR) wavelength region still require basic optical components such as sources and optical fibers as transmission medium. Thanks to its mid IR transparency and nonlinearity, tellurite glass allows for developing both these types of components. However, practical applications require materials able to handle high optical intensity through enhanced material damage threshold. We report on the synthesis of a tellurite glass in the TeO2-ZnO-La2O3 (TZL) system which presents enhanced thermo mechanical properties with respect to typical tellurite glass compositions. We measured for the TZL composition a glass transition of 626 K, hence 70 K higher than the glass transition temperature of “standard” TZN compositions. The coefficient of thermal expansion was measured to be 138.10-6/K as compared to typical value of 180.10-6/K for TZN glass. We manufactured two types of fibers to assess the prospect for achieving high average power SC sources and Mid IR transmission in TZL glass fibers. First, a high Numerical Aperture (NA) aperture fiber was developed through standard rod in tube technique, where the cladding glass tube was manufactured by extrusion. The 50 μm core fiber presents an optical attenuation value of 0.26 dB/m at 1.55 μm. As an intermediate step towards the fabrication of an antiresonant hollow core fiber for high power transmission, we manufactured a preform and drew it into a cane. A TZL glass tube, 120 mm long and 9 mm/12 mm of inner/outer diameters (ID/OD) was manufactured via rotational casting technique. This latter tube was drawn into a tube of 2 mm in diameter which was cut into sections 130 mm long. Seven of those were stacked in another tellurite glass tube 6.5 mm/12 mm of ID/OD diameters, respectively. This preform was then drawn into a microstructured cane 1.6 mm in diameter which features tubular structures periodically arranged and of uniform thickness

    DDHH, universidades, diversidad cultural y territorialidad: trabajo en redes, diálogo de saberes, aprendizajes y acciones compartidas con pueblos indígenas

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    En este texto se propone dar cuenta de experiencias de articulación de redes y trabajo conjuntos de instituciones y organizaciones diversas, donde se integran numerosas universidades, grupos artísticos, organizaciones y movimientos sociales (como es el caso de la Red Intercultural de Equipos de Acompañamiento Indígena –RIEDAI-) y redes de organizaciones de Comunidades y Pueblos Indígenas del Noroeste del país (OPINOA) en pos de hacer efectivas las prácticas de construcción de diálogos, intercambios e integración de saberes y prácticas que hacen a una interculturalidad activa garantizando así el respeto, ejercicio y promoción de Derechos Humanos como base de la vida colectiva común.Universidad Nacional de La Plat
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