Unraveling the inhomogeneously broadened absorption spectrum of conjugated polymers by single-molecule light-harvesting action spectroscopy

Journal ArticleThe distribution of chromophores in single polymer chains is revealed by photoluminescence excitation spectroscopy under excitation of the backbone and detection of emission from an end cap. Spectral broadening in excitation exceeds that in emission. An increase in vibronic coupling for shorter (higher energy) chromophores is resolved, leading to intrinsic spectral broadening and making higher energy units more effective donors. The results suggest routes to increasing absorption breadth while minimizing disorder as required for efficient photovoltaics

Simultaneous Raman and fluorescence spectroscopy of single conjugated polymer chains

Journal ArticleSimultaneous surface enhanced Raman scattering (SERS) and fluorescence is demonstrated from single conjugated polymer chains. As resonance enhancement of SERS depends on the spectral overlap of the polymer's absorption and the incident laser, resonance Raman and fluorescence effectively probe the absorbing and emitting part of the polymer, respectively. The optical phonon energies change along the polymer chain, providing a window to spatially track excited state relaxation. Whereas a mean spatial redistribution of the excitation is witnessed by a change in vibronic fingerprint following interchromophoric energy transfer, intrachromophoric exciton self-trapping leaves the vibrations unchanged

Physics and optimization of beta-beams: From low to very high gamma

The physics potential of beta beams is investigated from low to very high gamma values and it is compared to superbeams and neutrino factories. The gamma factor and the baseline are treated as continuous variables in the optimization of the beta beam, while a fixed mass water Cherenkov detector or a totally active scintillator detector is assumed. We include in our discussion also the gamma dependence of the number of ion decays per year. For low gamma, we find that a beta beam could be a very interesting alternative to a superbeam upgrade, especially if it is operated at the second oscillation maximum to reduce correlations and degeneracies. For high gamma, we find that a beta beam could have a potential similar to a neutrino factory. In all cases, the sensitivity of the beta beams to CP violation is very impressive if similar neutrino and anti-neutrino event rates can be achieved.Comment: 34 pages, 16 figures, Fig. 2 modified, discussion improved, refs. added, version to appear in PR

Determinant Bounds and the Matsubara UV Problem of Many-Fermion Systems

It is known that perturbation theory converges in fermionic field theory at weak coupling if the interaction and the covariance are summable and if certain determinants arising in the expansion can be bounded efficiently, e.g. if the covariance admits a Gram representation with a finite Gram constant. The covariances of the standard many--fermion systems do not fall into this class due to the slow decay of the covariance at large Matsubara frequency, giving rise to a UV problem in the integration over degrees of freedom with Matsubara frequencies larger than some Omega (usually the first step in a multiscale analysis). We show that these covariances do not have Gram representations on any separable Hilbert space. We then prove a general bound for determinants associated to chronological products which is stronger than the usual Gram bound and which applies to the many--fermion case. This allows us to prove convergence of the first integration step in a rather easy way, for a short--range interaction which can be arbitrarily strong, provided Omega is chosen large enough. Moreover, we give - for the first time - nonperturbative bounds on all scales for the case of scale decompositions of the propagator which do not impose cutoffs on the Matsubara frequency.Comment: 29 pages LaTe

Tissue engineered cartilage generated from human trachea using DegraPol® scaffold

Objective: To date numerous attempts have been undertaken to conquer the challenging problem of reconstructing long segmental tracheal defects, as yet without lasting success. Recently, employing concepts of tissue engineering in animals, cartilage-like constructs were transplanted in vivo. However, both the feasibility of fabricating tracheal replacements and the use of human tracheal chondrocytes (HTC) for tissue engineering are still under investigation. In this study, we optimized isolation and cultivation techniques for human tracheal cartilage, assessing the feasibility of seeding these cells onto a novel, three-dimensional (3-D) polyester-urethane polymer (DegraPol®). Methods: Human tracheal cartilage was harvested from the trachea of lung donors, digested in 0.3% collagenase II, and the condrocytes serially passaged every 7-9 days. Cells were also cultivated over agar plate during the total 6-8 weeks expansion phase. Thereafter, chondrocytes were seeded onto DegraPol® (pore sizes 150-200 μm) with a seeding density of 2.4×107/ml, and chondrocyte-polymer constructs maintained during in vitro static culture. Results: HTC displayed stable proliferation kinetics in monolayer culture with positive expression of collagen type II. Following polymer seeding, both cellular proliferation and extracellular matrix (ECM) production, as measured by MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) and glycosaminoglycan assays, continued over extended culture. Active growth of HTC on DegraPol® was further demonstrated by Alcian blue staining, with the histomorphological appearance of the construct resembling that of native cartilage. Scanning electron microscopy showed chondrocyte growth and ECM synthesis both on the surface and inside the porous scaffold, with a dense cell layer on the surface of the scaffold and a lower cell distribution in the scaffold's interior. Conclusions: The harvested chondrocytes from human trachea cartilage expand well in vitro and possess the ability to form new cartilage-like tissue when seeded onto DegraPol® matrix. However, improved culture conditions are needed to permit cellular growth throughout cell-polymer construct

Fractal nature in fat crystal networks

The determination of the mechanical and rheological characteristics of several plastic fats requires a detailed understanding of the microstructure of the fat crystal network aggregates. The fractal approach is useful for the characterization of this microstructure. This review begins with information on fractality and statistical self-similar structure. Estimations for fractal dimension by means of equations relating the volume fraction of solid fat to shear elastic modulus G’ in linear region are described. The influence of interesterification on fractal dimension decrease (from 2,46 to 2,15) for butterfat-canola oil blends is notable. This influence is not significant for fat blends without butterfat. The need for an increase in research concerning the relationship between fractality and rheology in plastic fats is emphasized.La determinación de las características mecánicas y reológicas de ciertas grasas plásticas requiere conocimientos detallados sobre las microestructuras de los agregados que forman la red de cristales grasos. El estudio de la naturaleza fractal de estas microestructuras resulta útil para su carac­terización. Este artículo de información se inicia con descripciones de la dimensión fractal y de la "autosimilitud estadística". A continuación se describe el cálculo de la dimensión fractal mediante ecuaciones que relacionan la fracción en volumen de grasa sólida con el módulo de recuperación (G') dentro de un comportamiento viscoelástico lineal. Se destaca la influencia que la interesterificación ejerce sobre la dimensión fractal de una mezcla de grasa láctea y aceite de canola (que pasa de 2,64 a 2,15). Esta influencia no se presenta en mezclas sin grasa láctea. Se insiste sobre la necesidad de incrementar las investi­gaciones sobre la relación entre reología y estructura fractal en grasas plásticas.Peer reviewe

Functional renormalization group approach to correlated fermion systems

Numerous correlated electron systems exhibit a strongly scale-dependent behavior. Upon lowering the energy scale, collective phenomena, bound states, and new effective degrees of freedom emerge. Typical examples include (i) competing magnetic, charge, and pairing instabilities in two-dimensional electron systems, (ii) the interplay of electronic excitations and order parameter fluctuations near thermal and quantum phase transitions in metals, (iii) correlation effects such as Luttinger liquid behavior and the Kondo effect showing up in linear and non-equilibrium transport through quantum wires and quantum dots. The functional renormalization group is a flexible and unbiased tool for dealing with such scale-dependent behavior. Its starting point is an exact functional flow equation, which yields the gradual evolution from a microscopic model action to the final effective action as a function of a continuously decreasing energy scale. Expanding in powers of the fields one obtains an exact hierarchy of flow equations for vertex functions. Truncations of this hierarchy have led to powerful new approximation schemes. This review is a comprehensive introduction to the functional renormalization group method for interacting Fermi systems. We present a self-contained derivation of the exact flow equations and describe frequently used truncation schemes. Reviewing selected applications we then show how approximations based on the functional renormalization group can be fruitfully used to improve our understanding of correlated fermion systems.Comment: Review article, final version, 59 pages, 28 figure

3',5'-Cyclic Adenosine Monophosphate- and Ca2+-Calmodulin-Dependent Endogenous Protein Phosphorylation Activity in Membranes of the Bovine Chromaffin Secretory Vesicles: Identification of Two Phosphorylated Components as Tyrosine Hydroxylase and Protein Kinase Regulatory Subunit Type II

Abstract: Membranes of the secretory vesicles from bovine adrenal medulla were investigated for the presence of the endogenous protein phosphorylation activity. Seven phosphoprotein bands in the molecular weight range of 250,000 to 30,000 were observed by means of the sodium dodecyl sulphate electrophoresis and autoradiography. On the basis of the criteria of molecular weight, selective stimulation of the phosphorylation by cyclic AMP (as compared with cyclic GMP) and immunoprecipitation by specific antibodies, band 5 (molecular weight 60,300) was found to represent the phosphorylated form of the secretory vesicle-bound tyrosine hydroxylase. The electrophoretic mobility, the stimulatory and inhibitory effects of cyclic AMP in presence of Mg2+ and Zn,2+ respectively, and immunoreactivity toward antibodies showed band 6 to contain two forms of the regulatory subunits of the type II cyclic AMP-dependent protein kinase, distinguishable by their molecular weights (56,000 and 52,000, respectively). Phosphorylation of band 7 (molecular weight 29,800) was stimulated about 2 to 3 times by Ca2+ and calmodulin in the concentration range of both agents believed to occur in the secretory tissues under physiological conditions

Self-productivity and complementarities in human development : evidence from MARS

This paper investigates the role of self-productivity and home resources in capability formation from infancy to adolescence. In addition, we study the complementarities between basic cognitive, motor and noncognitive abilities and social as well as academic achievement. Our data are taken from the Mannheim Study of Children at Risk (MARS), an epidemiological cohort study following the long-term outcome of early risk factors. Results indicate that initial risk conditions cumulate and that differences in basic abilities increase during development. Self-productivity rises in the developmental process and complementarities are evident. Noncognitive abilities promote cognitive abilities and social achievement. There is remarkable stability in the distribution of the economic and socio-emotional home resources during the early life cycle. This is presumably a major reason for the evolution of inequality in human development