2,849 research outputs found
Polygraph Admission Through Compulsory Process
Polygraph evidence is included within the broad category of expert testimony, yet it is treated quite differently from other forms of expert testimony. If admissible at all for the defense, polygraph evidence almost always requires the stipulation of the prosecution for it to be admitted into court. Such a requirement vests solely, within the hands of a prosecutor, the ability to eliminate that proof which may be necessary for the defendant to effectively prove his innocence. Furthermore, in some jurisdictions a defendant cannot even place his faith in the sympathy of a prosecutor. Instead, a rule bars him from proving his innocence. Such rules and requirements may very well deny the defendant his constitutional right to compulsory process
SOUTHERNMOST OCCURRENCE OF THE SUWANNEE COOTER, PSEUDEMYS CONCINNA SUWANNIENSIS (TESTUDINES: EMYDIDAE)
The Suwannee Cooter, Pseudemys concinna suwanniensis, the largest member of the speciose turtle family Emydidae, inhabits a small number of rivers that drain into the northeastern Gulf of Mexico along the northwest coast of Florida from just west of Tallahassee to just south of Tampa. The status of this state-protected subspecies in the southernmost of these rivers, the Alafia, is unknown and hence of conservation concern. We provide recent evidence confirming that a reproducing population still exists in this river, and review available specimens and both published and unpublished records documenting the southern limit of distribution. At least within the eastern United States, our observations also extend confirmed knowledge of the geographic occurrence of hatchling turtles overwintering in the nest southward by 285 km
Atrial fibrillation and survival in colorectal cancer
BACKGROUND: Survival in colorectal cancer may correlate with the degree of systemic inflammatory response to the tumour. Atrial fibrillation may be regarded as an inflammatory complication. We aimed to determine if atrial fibrillation is a prognostic factor in colorectal cancer. PATIENTS AND METHODS: A prospective colorectal cancer patient database was cross-referenced with the hospital clinical-coding database to identify patients who had underwent colorectal cancer surgery and were in atrial fibrillation pre- or postoperatively. RESULTS: A total of 175 patients underwent surgery for colorectal cancer over a two-year period. Of these, 13 patients had atrial fibrillation pre- or postoperatively. Atrial fibrillation correlated with worse two-year survival (p = 0.04; log-rank test). However, in a Cox regression analysis, atrial fibrillation was not significantly associated with survival. CONCLUSION: The presence or development of atrial fibrillation in patients undergoing surgery for colorectal cancer is associated with worse overall survival, however it was not found to be an independent factor in multivariate analysis
Resuscitation of the trauma patient: tell me a trigger for early haemostatic resuscitation please!
The management of trauma-related coagulopathy and haemorrhage is changing from a reactive strategy to a proactive early intervention with blood products and haemostatic agents. Although major haemorrhage and massive transfusion are associated with higher mortality, the pattern of this association with modern trauma care is poorly described. In addition, early predictors of massive transfusion, which might trigger a proactive haemostatic resuscitation strategy, are not currently available. We review recent literature relating to predictors of massive transfusions and the relationship between transfusion and mortality
Developing a Supply Chain Strategy for a Midsize Resturant Chain
In this paper, we develop a supply chain strategy for a growing midsize restaurant chain. Based on a case research of The HoneyBaked Ham Company of Ohio, we propose that an integrated approach should be applied to handle the challenges presented in the midsize restaurant distribution system. Specifically, we focus on action plans for mitigating inefficiencies found in the previous supply chain of HBH. As the success of supply chain management has increasingly become part of the competitive advantage of many firms, our work provides managerial insights to practitioners and researchers in the area of chain restaurant management where supply chain is often overlooked as a standard "back-office" function
SNAPPI-DB: a database and API of Structures, iNterfaces and Alignments for Protein–Protein Interactions
SNAPPI-DB, a high performance database of Structures, iNterfaces and Alignments of Protein–Protein Interactions, and its associated Java Application Programming Interface (API) is described. SNAPPI-DB contains structural data, down to the level of atom co-ordinates, for each structure in the Protein Data Bank (PDB) together with associated data including SCOP, CATH, Pfam, SWISSPROT, InterPro, GO terms, Protein Quaternary Structures (PQS) and secondary structure information. Domain–domain interactions are stored for multiple domain definitions and are classified by their Superfamily/Family pair and interaction interface. Each set of classified domain–domain interactions has an associated multiple structure alignment for each partner. The API facilitates data access via PDB entries, domains and domain–domain interactions. Rapid development, fast database access and the ability to perform advanced queries without the requirement for complex SQL statements are provided via an object oriented database and the Java Data Objects (JDO) API. SNAPPI-DB contains many features which are not available in other databases of structural protein–protein interactions. It has been applied in three studies on the properties of protein–protein interactions and is currently being employed to train a protein–protein interaction predictor and a functional residue predictor. The database, API and manual are available for download at:
DISTRIBUTION AND STATUS OF THE SUWANNEE COOTER, PSEUDEMYS CONCINNA SUWANNIENSIS, IN THE ALAFIA RIVER (HILLSBOROUGH COUNTY, FLORIDA, USA)
The Suwannee Cooter, Pseudemys concinna suwanniensis, is a geographically limited turtle of conservation concern that inhabits Florida rivers draining into the northeastern Gulf of Mexico. Threats impacting its conservation status include take for human consumption, predation of turtles and nests, loss or degradation of nesting and basking habitat, water quality degradation, and boat strikes. Our surveys revealed that the Alafia River, which drains into Hillsborough Bay (northeastern Tampa Bay), is likely the stronghold of the southern distribution of P. c. suwanniensis. Multiple survey methods during 2015-2020 revealed that a substantial population of Suwannee Cooters inhabits much of this blackwater river system, including the main channel and at least one of its two primary tributaries. GIS analysis showed that more than half of the shoreline within the occupied extent is currently protected by conservation lands, although additional protection of private lands and improved habitat management protocols are needed to assure the population’s conservation
Anthropological and socioeconomic factors contributing to global antimicrobial resistance: a univariate and multivariable analysis
Background
Understanding of the factors driving global antimicrobial resistance is limited. We analysed antimicrobial resistance and antibiotic consumption worldwide versus many potential contributing factors.
Methods
Using three sources of data (ResistanceMap, the WHO 2014 report on antimicrobial resistance, and contemporary publications), we created two global indices of antimicrobial resistance for 103 countries using data from 2008 to 2014: Escherichia coli resistance—the global average prevalence of E coli bacteria that were resistant to third-generation cephalosporins and fluoroquinolones, and aggregate resistance—the combined average prevalence of E coli and Klebsiella spp resistant to third-generation cephalosporins, fluoroquinolones, and carbapenems, and meticillin-resistant Staphylococcus aureus. Antibiotic consumption data were obtained from the IQVIA MIDAS database. The World Bank DataBank was used to obtain data for governance, education, gross domestic product (GDP) per capita, health-care spending, and community infrastructure (eg, sanitation). A corruption index was derived using data from Transparency International. We examined associations between antimicrobial resistance and potential contributing factors using simple correlation for a univariate analysis and a logistic regression model for a multivariable analysis.
Findings
In the univariate analysis, GDP per capita, education, infrastructure, public health-care spending, and antibiotic consumption were all inversely correlated with the two antimicrobial resistance indices, whereas higher temperatures, poorer governance, and the ratio of private to public health expenditure were positively correlated. In the multivariable regression analysis (confined to the 73 countries for which antibiotic consumption data were available) considering the effect of changes in indices on E coli resistance (R2 0·54) and aggregate resistance (R2 0·75), better infrastructure (p=0·014 and p=0·0052) and better governance (p=0·025 and p<0·0001) were associated with lower antimicrobial resistance indices. Antibiotic consumption was not significantly associated with either antimicrobial resistance index in the multivariable analysis (p=0·64 and p=0·070).
Interpretation
Reduction of antibiotic consumption will not be sufficient to control antimicrobial resistance because contagion—the spread of resistant strains and resistance genes—seems to be the dominant contributing factor. Improving sanitation, increasing access to clean water, and ensuring good governance, as well as increasing public health-care expenditure and better regulating the private health sector are all necessary to reduce global antimicrobial resistance
Star Formation in the Field and Clusters of NGC 5253
We investigate the star formation history of both the bright star clusters
and the diffuse `field star' population in the dwarf starburst galaxy NGC 5253
using STIS longslit ultraviolet spectroscopy. Our slit covers a physical area
of 370 x 1.6 pc and includes 8 apparent clusters and several inter-cluster
regions of diffuse light which we take to be the field. The diffuse light
spectrum lacks the strong O-star wind features which are clearly visible in
spectra of the brightest clusters. This discrepancy provides compelling
evidence that the diffuse light is not reflected light from nearby clusters,
but originates in a UV-bright field star population, and it raises the issue of
whether the star formation process may be operating differently in the field
than in clusters. We compare our spectra to STARBURST99 evolutionary synthesis
models which incorporate a new low metallicity atlas of O-star spectra. We
favor a scenario which accounts for the paucity of O-stars in the field without
requiring the field to have a different IMF than the clusters: stellar clusters
form continuously and then dissolve on ~10 Myr timescales and disperse their
remaining stars into the field. We consider the probable contribution of an
O-star deficient field population to the spatially unresolved spectra of high
redshift galaxies. (Abridged)Comment: 26 pages, 10 figures, accepted for publication in Ap
A national study of plasma use in critical care: clinical indications, dose and effect on prothrombin time
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