114 research outputs found

    Indiana LTAP Technology Showcase - Everyday GIS for Public Works

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    Embracing technology can be challenging for everyone. Indiana LTAP understands, and we plan to help by focusing on technologies that can improve your operations and create a positive change in your agency. Understanding GIS is at the top of the list. Starting from the basics, our presenter will show you how to get started, how to get the most out of this technology, and what tools are available for you and your crew every da

    Framingham risk prediction equations for incidence of cardiovascular disease using detailed measures for smoking

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    Current prediction models for risk of cardiovascular disease (CVD) incidence incorporate smoking as a dichotomous yes/no measure. However, the risk of CVD associated with smoking also varies with the intensity and duration of smoking and there is a strong association between time since quitting and the risk of disease onset. This study aims to develop improved risk prediction equations for CVD incidence incorporating intensity and duration of smoking and time since quitting. The risk of developing a first CVD event was evaluated using a Cox’s model for participants in the Framingham offspring cohort who attended the fourth examination (1988–92) between the ages of 30 and 74 years and were free of CVD (n=3751). The full models based on the smoking variables and other risk factors, and reduced models based on the smoking variables and non-laboratory risk factors demonstrated good discrimination, calibration and global fit. The incorporation of both time since quitting among past smokers and pack-years among current smokers resulted in better predictive performance as compared to a dichotomous current/non-smoker measure and a current/quitter/never smoker measure. Compared to never smokers, the risk of CVD incidence increased with pack-years. Risk among those quitting more than five years prior to the baseline exam and within five years prior to the baseline exam were similar and twice as high as that of never smokers. A CVD risk equation incorporating the effects of pack-years and time since quitting provides an improved tool to quantify risk and guide preventive care

    The Plant Ontology: A common reference ontology for plants

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    The Plant Ontology (PO) (http://www.plantontology.org) (Jaiswal et al., 2005; Avraham et al., 2008) was designed to facilitate cross-database querying and to foster consistent use of plant-specific terminology in annotation. As new data are generated from the ever-expanding list of plant genome projects, the need for a consistent, cross-taxon vocabulary has grown. To meet this need, the PO is being expanded to represent all plants. This is the first ontology designed to encompass anatomical structures as well as growth and developmental stages across such a broad taxonomic range. While other ontologies such as the Gene Ontology (GO) (The Gene Ontology Consortium, 2010) or Cell Type Ontology (CL) (Bard et al., 2005) cover all living organisms, they are confined to structures at the cellular level and below. The diversity of growth forms and life histories within plants presents a challenge, but also provides unique opportunities to study developmental and evolutionary homology across organisms

    Framingham risk prediction equations for incidence of cardiovascular disease using detailed measures for smoking

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Abstract
Current prediction models for risk of cardiovascular disease (CVD) incidence incorporate smoking as a dichotomous yes/no measure. However, the risk of CVD associated with smoking also varies with the intensity and duration of smoking and there is a strong association between time since quitting and the risk of disease onset. This study aims to develop improved risk prediction equations for CVD incidence incorporating intensity and duration of smoking and time since quitting.
The risk of developing a first CVD event was evaluated using a Cox's model for participants in the Framingham offspring cohort who attended the fourth examination (1988-92) between the ages of 30 and 74 years and were free of CVD (n=3751). The full models based on the smoking variables and other risk factors, and reduced models based on the smoking variables and non-laboratory risk factors demonstrated good discrimination, calibration and global fit. The incorporation of both time since quitting among past smokers and packyears among current smokers resulted in better predictive performance as compared to a dichotomous current/non-smoker measure and a current/quitter/never smoker measure. Compared to never smokers, the risk of CVD incidence increased with pack-years. Risk among those quitting more than five years prior to the baseline exam and within five years prior to the baseline exam were similar and twice as high as that of never smokers. A CVD risk equation incorporating the effects of pack-years and time since quitting provides an improved tool to quantify risk and guide preventive care

    Quantum bistability and spin current shot noise of a single quantum dot coupled to an optical microcavity

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    Here we explore spin dependent quantum transport through a single quantum dot coupled to an optical microcavity. The spin current is generated by electron tunneling between a single doped reservoir and the dot combined with intradot spin flip transitions induced by a quantized cavity mode. In the limit of strong Coulomb blockade, this model is analogous to the Jaynes-Cummings model in quantum optics and generates a pure spin current in the absence of any charge current. Earlier research has shown that in the classical limit where a large number of such dots interact with the cavity field, the spin current exhibits bistability as a function of the laser amplitude that drives the cavity. We show that in the limit of a single quantum dot this bistability continues to be present in the intracavity photon statistics. Signatures of the bistable photon statistics manifest themselves in the frequency dependent shot noise of the spin current despite the fact that the quantum mechanical average spin current no longer exhibits bistability. Besides having significance for future quantum dot based optoelectronic devices, our results shed light on the relation between bistability, which is traditionally viewed as a classical effect, and quantum mechanics

    Developing a Web Site to Provide Geologic Data and Map Products for Allen County, Indiana

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    This poster was presented at the 2007 meeting of the Digital Mapping Techniques Conference in Columbia, South Carolina, May 20-23, 2007.The Internet is becoming the medium of choice for delivering geologic information to both technical users and the general public. The Indiana Geological Survey (IGS) is currently creating a Web-based glacial and bedrock geologic map site for Allen County in northeastern Indiana. Allen County is the site of Fort Wayne, Indiana’s second largest city, and lies within IGS mapping and outreach priority areas based on population density and transportation corridors. This Web site provides detailed geologic information in an area that continues to experience pressure on natural resources by a large population and expanding transportation network. It is anticipated that the information from the Web site will be widely used by the general public and by industry and government entities. The Allen County Web site includes an Internet map server (IMS), as well as illustrations, educational summaries, and discussions of geologic maps, terrain images, and databases that complement the IMS. The site provides a front-end to the IGS enterprise geodatabases, which contain information used simultaneously for research and for viewing by the general public. The geodatabase systems allow maps and data to be efficiently created, managed, updated, and distributed. Maps provided on the Allen County Web site include: (1) digital elevation model terrain, (2) Landsat imagery, (3) surficial geology, (4) drift thickness, (5) bedrock topography, (6) bedrock geology, and (7) water-table elevation. Technical database information includes: (1) lithologic information compiled from water-well information in the Indiana Department of Natural Resources, Division of Water well records, (2) natural gamma-ray geophysical log data, (3) stratigraphic test hole data, and (4) petroleum-well data. The development of the Web site was funded by the IGS and the Central Great Lakes Geologic Mapping Coalition.U.S. Geological Surve

    Atomistic surface erosion and thin film growth modelled over realistic time scales

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    We present results of atomistic modelling of surface growth and sputtering using a multi-time scale molecular dynamics–on-the-fly kinetic Monte Carlo scheme which allows simulations to be carried out over realistic experimental times. The method uses molecular dynamics to model the fast processes and then calculates the diffusion barriers for the slow processes on-the-fly, without any preconceptions about what transitions might occur. The method is applied to the growth of metal and oxide materials at impact energies typical for both vapour deposition and magnetron sputtering. The method can be used to explain growth processes, such as the filling of vacancies and the formation of stacking faults. By tuning the variable experimental parameters on the computer, a parameter set for optimum crystalline growth can be determined. The method can also be used to model sputtering where the particle interactions with the surface occur at a higher energy. It is shown how a steady state can arise in which interstitial clusters are continuously being formed below the surface during an atom impact event which also recombine or diffuse to the surface between impact events. For fcc metals the near surface region remains basically crystalline during the erosion process with a pitted topography which soon attains a steady state roughness

    High resolution 3D chemical characterisation of a cadmium telluride solar cell by dynamic SIMS

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    Impurity elements such as chlorine and sulphur can have significant effects on the electrical performance of cadmium telluride (CdTe) solar cells. Here, the 3D distribution of such elements in a cadmium chloride treated CdTe device has been determined by high resolution dynamic SIMS, a novel technique that has not been applied to thin-film PV cells. It is found that as well as segregating to grain boundaries following treatment, chlorine also segregates to the CdS/CdTe interface. Conversely, sulphur shows a U-shaped diffusion profile. These results have potential implications for the processing thin-film CdTe devices

    Service use and access in young children with an intellectual disability or global developmental delay: associations with challenging behaviour

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    Background Challenging behaviours are frequently shown by children with an intellectual disability. This study documents service use within this population and explores its relationship with challenging behaviours and child and parent characteristics. Method Forty-nine mothers of young children with an intellectual disability or global developmental delay completed questionnaires focusing on child behaviour, parental mental health, and service use. Results Maternal mental health was not associated with services accessed. Cost of services accessed differed by topography of challenging behaviour for destruction of the environment or aggression. No differences were noted for self-injurious behaviour. Conclusion In this small study, topography of challenging behaviour impacts on the frequency and/or duration (and therefore cost) of community-based health care accessed. Behaviours that have external impact, such as aggression and destruction of the environment, are associated with a higher cost of services used, a pattern not noted for behaviours that had less external impact (e.g., self-injurious behaviour)
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