581 research outputs found

    Publications of the NASA Controlled Ecological Life Support System (CELSS) Program, 1979-1989

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    Publications of research sponsored by the NASA Controlled Ecological Life Support System (CELSS) Program from 1979 to 1989 are listed. The CELSS Program encompasses research and technology with the goal of developing an autonomous bioregenerative life support system that continually recycles the solid, liquid, and gaseous materials essential for human life. The bibliography is divided into four major subject areas: food production, nutritional requirements, waste management, and systems management and control

    Publications of the Space Physiology and Countermeasures Program, Cardiopulmonary Discipline: 1980-1990

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    A 10-year cumulative bibliography of publications resulting from research supported by the Cardiopulmonary Discipline of the Space Physiology and Countermeasures Program of NASA's Life Sciences Division is provided. Primary subjects included in this bibliography are Fluid Shifts, Cardiovascular Fitness, Cardiovascular Physiology, and Pulmonary Physiology. General physiology references are also included. Principal investigators whose research tasks resulted in publication are identified. Publications are identified by a record number corresponding with their entry in the Life Sciences Bibliographic Database, maintained at the George Washington University

    Bookmobile Service in Indiana: Its History, Its Present, and Its Future

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    Traditionally, the bookmobile has played an important role in meeting the needs of the reading public and in providing information to a broad segment of society. But in the past few years, bookmobiles have fallen on hard times, and their demise has long been predicted. They have fallen victim to such things as the gas crisis, construction of branch libraries, and automation

    Publications of the space physiology and countermeasures program, regulatory physiology discipline: 1980 - 1990

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    A 10-year cumulative bibliography of publications resulting from research supported by the Regulatory Physiology discipline of the Space Physiology and Countermeasures Program of NASA's Life Sciences Division is provided. Primary subjects included in this bibliography are circadian rhythms, endocrinology, fluid and electrolyte regulation, hematology, immunology, metabolism and nutrition, temperature regulation, and general regulatory physiology. General physiology references are also included. Principal investigators whose research tasks resulted in publication are identified by asterisk. Publications are identified by a record number corresponding with their entry in the Life Sciences Bibliographic Database, maintained at the George Washington University

    Publications of the space physiology and countermeasures program, Musculoskeletal Discipline: 1980-1990

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    A 10-year cumulative bibliography of publications resulting from research supported by the musculoskeletal discipline of the space physiology and countermeasures program of NASA's Life Sciences Division is provided. Primary subjects are bone, mineral, and connective tissue, and muscle. General physiology references are also included. Principal investigators whose research tasks resulted in publication are identified by asterisk. Publications are identified by a record number corresponding with their entry in the life sciences bibliographic database, maintained by the George Washington University

    STUDIES OF GENETIC TRANSMISSION OF MURINE LEUKEMIA VIRUS BY AKR MICE : II. CROSSES WITHFv-1b STRAINS OF MICE

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    The transmission of murine leukemia virus (MLV) to hybrids between AKR and Fv-1b mice was studied in order to evaluate the effect of the Fv-1 gene on endogenous MLV infection and to attempt to determine if the genetic loci contributed by AKR carry viral genetic determinants. Fv-1 was shown to have a marked suppressive effect on time of appearance of detectable infectious virus and on the titers attained in vivo, but did not affect the ability of the cells to produce virus in vitro after induction with 5-iododeoxyuridine. The host range type of the virus detected in the hybrid mice was almost always of the type carried by AKR, although the low-virus Fv-1b parents carry the genome of a different host range type. This finding provides strong, but not conclusive, evidence that the virus-inducing loci of AKR contain MLV genetic determinants

    The Limits of Judicial Review in Constitutional Adjudication

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    Constitutional adjudication presently requires that in order for a party to challenge a governmental act he must claim that the act has violated his constitutional rights. The purpose of this article is to show that such a requirement undermines constitutional limits on governmental actions and is inconsistent with a proper interpretation of the Constitution. I. Introduction II. The Police Power III. The Government Operations Power IV. The Law Declaration Power V. Conclusio

    A MAJOR GENETIC LOCUS AFFECTING RESISTANCE TO INFECTION WITH MURINE LEUKEMIA VIRUSES : I. TISSUE CULTURE STUDIES OF NATURALLY OCCURRING VIRUSES

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    Previous studies have indicated that all naturally occurring murine leukemia viruses propagate significantly more efficiently on embryo cells of either NIH Swiss or BALB/c mice. Studies of the plaquing efficiency of representative viruses on embryo cells of various inbred and hybrid mice indicate that the pattern of sensitivity of the cells is genetically determined. All of 23 strains tested were found to resemble either NIH Swiss (N-type) or BALB/c (B-type) with respect to plaquing efficiency of these viruses. Virus growth on embryo cells derived from (N-type x B-type)F1 hybrids indicated dominance of resistance to both types of viruses. Backcross hybrid studies indicated that a single locus is the primary determinant of the host-range patterns observed. This locus has no effect on growth of certain laboratory-passaged leukemia viruses which propagate equally well on embryo cells of all mouse strains, F1, and backcross hybrids. Though other genetic and nongenetic factors influence viral growth or expression in vitro and in vivo, the genetic locus described appears of major significance in the biology of murine leukemia

    “The Impact of Micro-simulation and CGE modeling on Tax Reform and Tax Advice in Developing Countries”: A Survey of Alternative Approaches and an Application to Pakistan

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    Computational general equilibrium models (CGE) and micro-simulation models (MSM) each have their own sets of strengths and weaknesses. Both have been widely used for the analysis of fiscal policies in developing countries, and many attempts have been made to link the two models, thereby combining their relative strengths. We survey a broad literature that uses a variety of approaches to apply linked CGE and MSM models to analyze fiscal policies, in particular taxes and tariffs, in developing countries. We conclude that the “top down” approach, in which the aggregate outputs of the CGE model feed into the MSM, is the most commonly used. Nonetheless, a “bottom up” approach, in which the MSM generates estimated parameters, such as effective tax rates, which are then used as inputs to the CGE, may also be quite useful. As an example, we also develop both CGE and MSM models of Pakistan in order to indicate the relative uses of each model, although we have not at this time linked the two models

    Marjolin\u27s Tumor Complicating Chronic Periprosthetic Infection of a Total Knee Arthroplasty

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    Marjolin\u27s tumor is a term used to describe a malignancy developing in the setting of a chronic wound, infection, or other tissue subject to chronic inflammatory changes. These malignancies usually present after many years of chronicity, and can range from lower grade basal cell carcinomas to high-grade sarcomas. We present the case of a squamous cell carcinoma that developed within a chronic periprosthetic infection of a total knee arthroplasty of 7 years duration. The intra-articular location, association with an orthopaedic implant, and brief latency period are all unique features of this case
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