875 research outputs found
\u3cem\u3eShort Communication\u3c/em\u3e: Effect of Storage Temperature on the Solubility of Milk Protein Concentrate 80 (MPC80) Treated with NaCL or KCL
A previous study in our laboratory showed that addition of 150 mM NaCl or KCl into diafiltration water improved the solubility of freshly made milk protein concentrate 80 (MPC80). In the present study, the objectives were (1) to evaluate the solubility of NaCl- or KCl-treated MPC80 samples kept at varying temperatures and then stored for extensive periods at room temperature (21°C ± 1°C); and (2) to determine if MPC80 samples stored at different temperatures and protein conformation can be grouped or categorized together. Freshly manufactured MPC80 samples were untreated (control), processed with NaCl, or processed with KCl. One set of sample bags was stored at 4°C; second and third sets of bags were kept at 25°C and 55°C for 1 mo (31 d) and then transferred to room temperature (21°C ± 1°C) storage conditions for 1 yr (365 d). Samples were tested for nitrogen solubility index (NSI) and for protein changes by Fourier-transform infrared (FTIR) spectroscopy. Analysis of variance results for NSI showed 2 significantly different groupings of MPC80 samples. The more soluble group contained samples treated with NaCl or KCl and stored at either 4°C or 25°C. These samples had mean NSI \u3e97.5%. The less soluble groups contained all control samples, regardless of storage temperature, and NaCl- or KCl-treated samples stored at 55°C. These samples had mean NSI from 39.5 to 58%. Within each of these groups (more soluble and less soluble), no significant differences in solubility were detected. Pattern recognition analysis by soft independent modeling of class analogy (SIMCA) was used to assess protein changes during storage by monitoring the amide I and amide II (1,700â1 to 1,300 cmâ1) regions. Dominant bands were observed at 1,385 cmâ1 for control, 1,551 cmâ1 for KCl-treated samples, and 1,694 cmâ1 for NaCl-treated samples. Moreover, SIMCA clustered the MPC80 samples stored at 4°C separately from samples stored at 25°C and 55°C. This study demonstrates that (1) the addition of NaCl or KCl during MPC80 manufacture reduces the deleterious changes in solubility upon prolonged storage at 4°C or 25°C, and (2) the solubility of samples stored at 55°C is poor irrespective of salt treatment
Confined granular packings: structure, stress, and forces
The structure and stresses of static granular packs in cylindrical containers
are studied using large-scale discrete element molecular dynamics simulations
in three dimensions. We generate packings by both pouring and sedimentation and
examine how the final state depends on the method of construction. The vertical
stress becomes depth-independent for deep piles and we compare these stress
depth-profiles to the classical Janssen theory. The majority of the tangential
forces for particle-wall contacts are found to be close to the Coulomb failure
criterion, in agreement with the theory of Janssen, while particle-particle
contacts in the bulk are far from the Coulomb criterion. In addition, we show
that a linear hydrostatic-like region at the top of the packings unexplained by
the Janssen theory arises because most of the particle-wall tangential forces
in this region are far from the Coulomb yield criterion. The distributions of
particle-particle and particle-wall contact forces exhibit
exponential-like decay at large forces in agreement with previous studies.Comment: 11 pages, 11 figures, submitted to PRE (v2) added new references,
fixed typo
A lower limit on the dark particle mass from dSphs
We use dwarf spheroidal galaxies as a tool to attempt to put precise lower
limits on the mass of the dark matter particle, assuming it is a sterile
neutrino. We begin by making cored dark halo fits to the line of sight velocity
dispersions as a function of projected radius (taken from Walker et al. 2007)
for six of the Milky Way's dwarf spheroidal galaxies. We test Osipkov-Merritt
velocity anisotropy profiles, but find that no benefit is gained over constant
velocity anisotropy. In contrast to previous attempts, we do not assume any
relation between the stellar velocity dispersions and the dark matter ones, but
instead we solve directly for the sterile neutrino velocity dispersion at all
radii by using the equation of state for a partially degenerate neutrino gas
(which ensures hydrostatic equilibrium of the sterile neutrino halo). This
yields a 1:1 relation between the sterile neutrino density and velocity
dispersion, and therefore gives us an accurate estimate of the Tremaine-Gunn
limit at all radii. By varying the sterile neutrino particle mass, we locate
the minimum mass for all six dwarf spheroidals such that the Tremaine-Gunn
limit is not exceeded at any radius (in particular at the centre). We find
sizeable differences between the ranges of feasible sterile neutrino particle
mass for each dwarf, but interestingly there exists a small range 270-280eV
which is consistent with all dSphs at the 1- level.Comment: 13 pages, 2 figures, 1 tabl
Required duration of mass ivermectin treatment for onchocerciasis elimination in Africa: a comparative modelling analysis
Background: The World Health Organization (WHO) has set ambitious targets for the elimination of onchocerciasis by 2020-2025 through mass ivermectin treatment. Two different mathematical models have assessed the feasibility of reaching this goal for different settings and treatment scenarios, namely the individual-based microsimulation model ONCHOSIM and the population-based deterministic model EPIONCHO. In this study, we harmonize some crucial assumptions and compare model predictions on common outputs. Methods: Using a range of initial endemicity levels and treatment scenarios, we compared the models with respect to the following outcomes: 1) model-predicted trends in microfilarial (mf) prevalence and mean mf intensity during 25 years of (annual or biannual) mass ivermectin treatment; 2) treatment duration needed to bring mf prevalence below a provisional operational threshold for treatment interruption (pOTTIS, i.e. 1.4 %), and 3) treatment duration needed to drive the parasite population to local elimination, even in the absence of further interventions. Local elimination was judged by stochastic fade-out in ONCHOSIM and by reaching transmission breakpoints in EPIONCHO. Results: ONCHOSIM and EPIONCHO both predicted that in mesoendemic areas the pOTTIS can be reached with annual treatment, but that this strategy may be insufficient in very highly hyperendemic areas or would require prolonged continuation of treatment. For the lower endemicity levels explored, ONCHOSIM predicted that the time needed to reach the pOTTIS is longer than that needed to drive the parasite population to elimination, whereas for the higher endemicity levels the opposite was true. In EPIONCHO, the pOTTIS was reached consistently sooner than the breakpoint. Co
Indirect Dark Matter Detection from Dwarf Satellites: Joint Expectations from Astrophysics and Supersymmetry
We present a general methodology for determining the gamma-ray flux from
annihilation of dark matter particles in Milky Way satellite galaxies, focusing
on two promising satellites as examples: Segue 1 and Draco. We use the
SuperBayeS code to explore the best-fitting regions of the Constrained Minimal
Supersymmetric Standard Model (CMSSM) parameter space, and an independent MCMC
analysis of the dark matter halo properties of the satellites using published
radial velocities. We present a formalism for determining the boost from halo
substructure in these galaxies and show that its value depends strongly on the
extrapolation of the concentration-mass (c(M)) relation for CDM subhalos down
to the minimum possible mass. We show that the preferred region for this
minimum halo mass within the CMSSM with neutralino dark matter is ~10^-9-10^-6
solar masses. For the boost model where the observed power-law c(M) relation is
extrapolated down to the minimum halo mass we find average boosts of about 20,
while the Bullock et al (2001) c(M) model results in boosts of order unity. We
estimate that for the power-law c(M) boost model and photon energies greater
than a GeV, the Fermi space-telescope has about 20% chance of detecting a dark
matter annihilation signal from Draco with signal-to-noise greater than 3 after
about 5 years of observation
Backward Cherenkov radiation emitted by polariton solitons in a microcavity wire
Exciton-polaritons in semiconductor microcavities form a highly nonlinear platform to study a variety of effects interfacing optical, condensed matter, quantum and statistical physics. We show that the complex polariton patterns generated by picosecond pulses in microcavity wire waveguides can be understood as the Cherenkov radiation emitted by bright polariton solitons, which is enabled by the unique microcavity polariton dispersion, which has momentum intervals with positive and negative group velocities. Unlike in optical fibres and semiconductor waveguides, we observe that the microcavity wire Cherenkov radiation is predominantly emitted with negative group velocity and therefore propagates backwards relative to the propagation direction of the emitting soliton. We have developed a theory of the microcavity wire polariton solitons and of their Cherenkov radiation and conducted a series of experiments, where we have measured polariton-soliton pulse compression, pulse breaking and emission of the backward Cherenkov radiation
New empirical fits to the proton electromagnetic form factors
Recent measurements of the ratio of the elastic electromagnetic form factors
of the proton, G_Ep/G_Mp, using the polarization transfer technique at
Jefferson Lab show that this ratio decreases dramatically with increasing Q^2,
in contradiction to previous measurements using the Rosenbluth separation
technique. Using this new high quality data as a constraint, we have reanalyzed
most of the world e-p elastic cross section data. In this paper, we present a
new empirical fit to the reanalyzed data for the proton elastic magnetic form
factor in the region 0 < Q^2 < 30 GeV^2. As well, we present an empirical fit
to the proton electromagnetic form factor ratio, G_Ep/G_Mp, which is valid in
the region 0.1 < Q^2 < 6 GeV^2
A critical reassessment of particle Dark Matter limits from dwarf satellites
Dwarf satellite galaxies are ideal laboratories for identifying particle Dark Matter signals. When setting limits on particle Dark Matter properties from null searches, it becomes however crucial the level at which the Dark Matter density profile within these systems is constrained by observations. In the limit in which the spherical Jeans equation is assumed to be valid for a given tracer stellar population, we study the solution of this equation having the Dark Matter mass profile as an output rather than as a trial parametric input. Within our new formulation, we address to what level dwarf spheroidal galaxies feature a reliable mass estimator. We assess then possible extrapolation of the density profiles in the inner regions and -- keeping explicit the dependence on the orbital anisotropy profile of the tracer population -- we derive general trends on the line-of-sight integral of the density profile squared, a quantity commonly dubbed J-factor and crucial to estimate fluxes from prompt Dark Matter pair annihilations. Taking Ursa Minor as a study case among Milky Way satellites, we perform Bayesian inference using the available kinematical data for this galaxy. Contrary to all previous studies, we avoid marginalization over quantities poorly constrained by observations or by theoretical arguments. We find minimal J-factors to be about 2 to 4 times smaller than commonly quoted estimates, approximately relaxing by the same amount the limit on Dark Matter pair annihilation cross section from gamma-ray surveys of Ursa Minor. At the same time, if one goes back to a fixed trial parametric form for the density, e.g. using a NFW or Burkert profile, we show that the minimal J can hardly be reduced by more than a factor of 1.5. \ua9 2016 IOP Publishing Ltd and Sissa Medialab srl
Dark Matter signals from Draco and Willman 1: Prospects for MAGIC II and CTA
The next generation of ground-based Imaging Air Cherenkov Telescopes (IACTs)
will play an important role in indirect dark matter searches. In this article,
we consider two particularly promising candidate sources for dark matter
annihilation signals, the nearby dwarf galaxies Draco and Willman 1, and study
the prospects of detecting such a signal for the soon-operating MAGIC II
telescope system as well as for the planned installation of CTA, taking special
care of describing the experimental features that affect the detectional
prospects. For the first time in such a study, we fully take into account the
effect of internal bremsstrahlung, which has recently been shown to
considerably enhance, in some cases, the gamma-ray flux at the high energies
where Atmospheric Cherenkov Telescopes operate, thus leading to significantly
harder annihilation spectra than traditionally considered. While the detection
of the spectral features introduced by internal bremsstrahlung would constitute
a smoking gun signature for dark matter annihilation, we find that for most
models the overall flux still remains at a level that will be challenging to
detect unless one adopts rather (though by no means overly) optimistic
astrophysical assumptions about the distribution of dark matter in the dwarfs.Comment: 10 pages, 4 figures, minor changes, matches the published version
(JCAP
An efficient algorithm to calculate intrinsic thermoelectric parameters based on Landauer approach
The Landauer approach provides a conceptually simple way to calculate the
intrinsic thermoelectric (TE) parameters of materials from the ballistic to the
diffusive transport regime. This method relies on the calculation of the number
of propagating modes and the scattering rate for each mode. The modes are
calculated from the energy dispersion (E(k)) of the materials which require
heavy computation and often supply energy relation on sparse momentum (k)
grids. Here an efficient method to calculate the distribution of modes (DOM)
from a given E(k) relationship is presented. The main features of this
algorithm are, (i) its ability to work on sparse dispersion data, and (ii)
creation of an energy grid for the DOM that is almost independent of the
dispersion data therefore allowing for efficient and fast calculation of TE
parameters. The inclusion of scattering effects is also straight forward. The
effect of k-grid sparsity on the compute time for DOM and on the sensitivity of
the calculated TE results are provided. The algorithm calculates the TE
parameters within 5% accuracy when the K-grid sparsity is increased up to 60%
for all the dimensions (3D, 2D and 1D). The time taken for the DOM calculation
is strongly influenced by the transverse K density (K perpendicular to
transport direction) but is almost independent of the transport K density
(along the transport direction). The DOM and TE results from the algorithm are
bench-marked with, (i) analytical calculations for parabolic bands, and (ii)
realistic electronic and phonon results for .Comment: 16 Figures, 3 Tables, submitted to Journal of Computational
electronic
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