8,366 research outputs found

    PRODUCT CHARACTERISTICS AFFECTING CONSUMERS' FRESH BEEF CUT PURCHASING DECISIONS IN THE UNITED STATES, JAPAN, AND AUSTRALIA

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    The effects of product and economic characteristics on consumers who purchase six cuts of fresh beef (blocks/parts, steak, thinly sliced, diced, chopped, and ground) in urban areas of the United States, Japan, and Australia will be examined in this paper. Certain product characteristics (such as product freshness and display case cleanliness) were important to consumers of beef in all three countries while other product characteristics (such as price considerations for ground beef consumers) were important for consumers of different beef cuts in all three countries. Some product characteristics varied in importance across consumers from different countries and consumers of different beef cuts.Consumer/Household Economics,

    Differences Between Women Administrators and Faculty

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    This article investigates the differences between women administrators and faculty at the Colorado University. Of the three groups, the faculty scored closest to an androgynous rating, the current administrators more masculine, and the former administrators the most masculine. It is important to remember that definitions of masculinity and femininity are generated by the respondent\u27s self-perception of traits consonant with sex-role stereotypes and not by conformity to any generalized principle of masculinity or femininity. Thus, administrators perceived themselves as fitting best with stereotypical assumptions of masculine qualities, while faculty perceived themselves to fit best with androgynous characteristics

    Quantum Coherence of Image-Potential States

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    The quantum dynamics of the two-dimensional image-potential states in front of the Cu(100) surface is measured by scanning tunneling microscopy (STM) and spectroscopy (STS). The dispersion relation and the momentum resolved phase-relaxation time of the first image-potential state are determined from the quantum interference patterns in the local density of states (LDOS) at step edges. It is demonstrated that the tip-induced Stark shift does not affect the motion of the electrons parallel to the surface.Comment: Submitted to Phys. Rev. Lett., 4 pages, 4 figures; corrected typos, minor change

    Coronary artery spasm and non-Q-wave myocardial infarction following intravenous ephedrine in two healthy women under spinal anaesthesia

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    Vasovagal episodes occur frequently in young healthy patients undergoing venous cannulation and loco-regional anaesthesia. We report two cases of severe coronary vasospasm and non-Qwave infarction in healthy young women after administration of ephedrine for vasovagal symptoms at the onset of spinal anaesthesia. In the light of unopposed vagal predominance predisposing patients to coronary vasospasm, even in young healthy patients, atrophine and not ephedrine should be the first line treatment for bradycardia with or without hypotension under spinal anaesthesi

    Deformed two center shell model

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    A highly specialized two-center shell model has been developed accounting for the splitting of a deformed parent nucleus into two ellipsoidaly deformed fragments. The potential is based on deformed oscillator wells in direct correspondance with the shape change of the nuclear system. For the first time a potential responsible for the necking part between the fragments is introduced on potential theory basis. As a direct consequence, spin-orbit {\bf ls} and {\bf l2^2} operators are calculated as shape dependent. Level scheme evolution along the fission path for pairs of ellipsoidaly deformed fragments is calculated. The Strutinsky method yields the shell corrections for different mass asymmetries from the superheavy nucleus 306^{306}122 and 252^{252}Cf all along the splitting process.Comment: 32 pages, 8 figure

    Spectral Analysis Using Regularized Non-Negative Least-Squares Estimation

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    The implementation of spectral analysis techniques involves solving a highly underdetermined linear system equation and is prone to the effect of measurement noise. The authors propose to use a regularized non-negative least-square estimator to stabilize the implementation of the technique. They introduce a penalty term in their formulation of the function to discourage disparities in tracer kinetics between neighboring pixels and use an iterative method to impose positivity constraints. The authors show results from analysis of FDG thorax images of patients suspected to have cancers and summarize their findings.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/85892/1/Fessler137.pd

    Hydrology of the surficial aquifer in the Floyd River Basin, Iowa

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    https://ir.uiowa.edu/igs_wsb/1011/thumbnail.jp

    Structure and function of an RNase H domain at the heart of the spliceosome.

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    Precursor-messenger RNA (pre-mRNA) splicing encompasses two sequential transesterification reactions in distinct active sites of the spliceosome that are transiently established by the interplay of small nuclear (sn) RNAs and spliceosomal proteins. Protein Prp8 is an active site component but the molecular mechanisms, by which it might facilitate splicing catalysis, are unknown. We have determined crystal structures of corresponding portions of yeast and human Prp8 that interact with functional regions of the pre-mRNA, revealing a phylogenetically conserved RNase H fold, augmented by Prp8-specific elements. Comparisons to RNase H–substrate complexes suggested how an RNA encompassing a 5′-splice site (SS) could bind relative to Prp8 residues, which on mutation, suppress splice defects in pre-mRNAs and snRNAs. A truncated RNase H-like active centre lies next to a known contact region of the 5′SS and directed mutagenesis confirmed that this centre is a functional hotspot. These data suggest that Prp8 employs an RNase H domain to help assemble and stabilize the spliceosomal catalytic core, coordinate the activities of other splicing factors and possibly participate in chemical catalysis of splicing

    Palmitoylation of Desmoglein 2 Is a Regulator of Assembly Dynamics and Protein Turnover.

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    Desmosomes are prominent adhesive junctions present between many epithelial cells as well as cardiomyocytes. The mechanisms controlling desmosome assembly and remodeling in epithelial and cardiac tissue are poorly understood. We recently identified protein palmitoylation as a mechanism regulating desmosome dynamics. In this study, we have focused on the palmitoylation of the desmosomal cadherin desmoglein-2 (Dsg2) and characterized the role that palmitoylation of Dsg2 plays in its localization and stability in cultured cells. We identified two cysteine residues in the juxtamembrane (intracellular anchor) domain of Dsg2 that, when mutated, eliminate its palmitoylation. These cysteine residues are conserved in all four desmoglein family members. Although mutant Dsg2 localizes to endogenous desmosomes, there is a significant delay in its incorporation into junctions, and the mutant is also present in a cytoplasmic pool. Triton X-100 solubility assays demonstrate that mutant Dsg2 is more soluble than wild-type protein. Interestingly, trafficking of the mutant Dsg2 to the cell surface was delayed, and a pool of the non-palmitoylated Dsg2 co-localized with lysosomal markers. Taken together, these data suggest that palmitoylation of Dsg2 regulates protein transport to the plasma membrane. Modulation of the palmitoylation status of desmosomal cadherins can affect desmosome dynamics
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