4,548 research outputs found

    Estimating Sensor Motion from Wide-Field Optical Flow on a Log-Dipolar Sensor

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    Log-polar image architectures, motivated by the structure of the human visual field, have long been investigated in computer vision for use in estimating motion parameters from an optical flow vector field. Practical problems with this approach have been: (i) dependence on assumed alignment of the visual and motion axes; (ii) sensitivity to occlusion form moving and stationary objects in the central visual field, where much of the numerical sensitivity is concentrated; and (iii) inaccuracy of the log-polar architecture (which is an approximation to the central 20°) for wide-field biological vision. In the present paper, we show that an algorithm based on generalization of the log-polar architecture; termed the log-dipolar sensor, provides a large improvement in performance relative to the usual log-polar sampling. Specifically, our algorithm: (i) is tolerant of large misalignmnet of the optical and motion axes; (ii) is insensitive to significant occlusion by objects of unknown motion; and (iii) represents a more correct analogy to the wide-field structure of human vision. Using the Helmholtz-Hodge decomposition to estimate the optical flow vector field on a log-dipolar sensor, we demonstrate these advantages, using synthetic optical flow maps as well as natural image sequences

    No. 08: The Urban Food System of Windhoek, Namibia

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    The surprisingly high rate of supermarket patronage in low-income areas of Windhoek, Namibia’s capital and largest city, is at odds with conventional wisdom that supermarkets in African cities are primarily patronized by middle and high-income residents and therefore target their neighbourhoods. What is happening in Namibia and other Southern African countries that make supermarkets so much more accessible to the urban poor? What are they buying at supermarkets and how frequently do they shop there? Further, what is the impact of supermarket expansion on informal food vendors? This report, which presents the findings of the South African Supermarkets in Growing African Cities project research in 2016-2017 in Windhoek, looks at the evidence and tries to answer these questions and others. The research and policy debate on the relationship between the supermarket revolution and food security is also discussed. Here, the issues include whether supermarket supply chains and procurement practices mitigate rural food insecurity through providing new market opportunities for smallholder farmers; the impact of supermarkets on the food security and consumption patterns of residents of African cities; and the relationship between supermarket expansion and governance of the food system, particularly at the local level

    No. 26: The Supermarket Revolution and Food Security in Namibia

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    The surprisingly high rate of supermarket patronage in low-income areas of Windhoek, Namibia’s capital and largest city, is at odds with conventional wisdom that supermarkets in African cities are primarily patronized by middle and high-income residents and therefore target their neighbourhoods. What is happening in Namibia and other Southern African countries that make supermarkets so much more accessible to the urban poor? What are they buying at supermarkets and how frequently do they shop there? Further, what is the impact of supermarket expansion on informal food vendors? This report, which presents the findings from the South African Supermarkets in Growing African Cities project research in 2016-2017 in Windhoek, looks at the evidence and tries to answer these questions and others. The research and policy debate on the relationship between the supermarket revolution and food security is also discussed. Here, the issues include whether supermarket supply chains and procurement practices mitigate rural food insecurity through providing new market opportunities for smallholder farmers; the impact of supermarkets on the food security and consumption patterns of residents of African cities; and the relationship between supermarket expansion and governance of the food system, particularly at the local level

    Nazi Party Membership in Canada: A Profile

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    Perioperative Management in Patients with Chronic Obstructive Pulmonary Disease

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    Introduction: Chronic obstructive pulmonary disease (COPD) results in three million deaths a year globally; COPD is becoming the third leading cause of death worldwide (Shin et al., 2017). The prevalence of COPD has a significant impact on the delivery of anesthesia in surgery. Purpose: This poster analyzes risk factors associated with COPD and the complications associated with the disease. The implications and nursing considerations are outlined to direct goals of care and ventilator management during surgery. Methodology: The data was collected from various control trials and meta-analysis studies. Information was also derived from pathophysiology and anesthesia resources. Results: Patients with COPD were found to be higher risk for the development of postoperative pulmonary complications (PPCs) (Bustamante et al., 2017). COPD also caused patients to have extended extubation times compared to patients without COPD. Conclusions: The risk of PPCs can be minimized with appropriate nursing interventions including small tidal volumes, prolonged expiratory phases, and fluid restriction during surgery

    No. 06: The Urban Food System of Nairobi, Kenya

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    Nairobi is a city of stark contrasts. Nearly half a million of its three million residents live in abject poverty in some of Africa’s largest slums, yet the Kenyan capital is also an international and regional hub. In East Africa, rapid urbanization is stretching existing food and agriculture systems as growing cities struggle to provide food and nutrition security for their inhabitants. Nairobi is no exception; it is a dynamically growing city and its food supply chains are constantly adapting and responding to changing local conditions. It is also an international city and the extent to which it is food secure is increasingly predicated on food imports from the regional East African Community and other international sources. Informal traditional value chains have a variety of actors and intermediaries that increase transaction costs and create an inefficient post-harvest procurement network, thereby pushing food products out of the reach of those who need them most. The majority of Nairobi’s food purchases are from informal food vendors. The city’s urban poor rely on the informal food sector for several reasons including that it provides food close to where they live and work, credit and barter are often available, small quantities can be purchased, and many items are sold more cheaply than at formal outlets. The leading income-generating activity for women in Nairobi’s poor communities is selling fruit and vegetables

    Dopaminergic Modulation of Intertemporal Choice

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    The overall goal of the studies presented in this dissertation is to improve our understanding of dopamine (DA)-associated changes in intertemporal preferences. Understanding these DA-mediated relationships is essential to our understanding of the continuous dimensions of human functioning and the promise of the RDoC framework (U.S. Department of Health and Human Services, National Institutes of 2016). Study 1 in this dissertation investigates DAergic modulation of intertemporal choice in healthy adult participants using the DA D2-receptor antagonist haloperidol and state-of-the-art computational approaches to further decompose the decision-process. Study 2 takes behavioral testing beyond the lab into real-life environments and assesses the effects of addiction related environments on intertemporal preferences and model-based reinforcement learning in regular slot machine gamblers. In Study 3 we examine whether patients with Tourette Syndrome show aberrations in intertemporal choice. This is of particular interest because Tourette Syndrome is associated with reward sensitivity and disturbances in DA neurotransmission. In Study 4 we investigate short- and long-term stability of intertemporal preferences as a function of acute and chronic deep brain stimulation in a cohort of Obsessive-Compulsive Disorder patients

    STRUCTURAL BASIS OF SUBSTRATE RECOGNITION IN THIMET OLIGOPEPTIDASE AND DEVELOPMENT OF NANOPARTICLES FOR THERAPEUTIC ENZYME DELIVERY

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    Neuropeptidases are responsible for degradation of signaling peptides in the central nervous system and periphery. Some neuropeptidases have also been shown to play a role as part of the cell’s hydrolytic machinery responsible for breaking down proteins and peptides into amino acids, and these enzymes therefore influence small peptide availability for antigen presentation. A better understanding of how neuropeptidases recognize their substrates could lead to therapeutics that modulate the activity of these important enzymes. Alternatively, re-engineering these enzymes to selectively hydrolyze undesirable peptides could make them attractive as therapeutics themselves. A key question in understanding the activity of these enzymes is how they are able to recognize a variety of seemingly unrelated amino acid sequences as cleavage sites. We are investigating the basis for this general substrate recognition in neuropeptidases using thimet oligopeptidase (TOP) as a model. Crystal structures of TOP in complex with a variety of substrates and inhibitors shed light on the mechanisms underlying substrate recognition and pave the way for re-targeting substrate recognition in these enzymes. Nano test tube particles have been proposed as a means of delivering therapeutics such as enzymes. However, the template synthesis method for nano test tube production does not produce therapeutic quantities. In order to take full advantage of re-engineered neuropeptidases a new method for nano test tube synthesis has been developed. We show that a non-destructive template synthesis methodology can be applied to produce nano test tube particles in quantities useful for therapeutic enzyme immobilization
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