50,861 research outputs found
The application of remote sensing techniques: Technical and methodological issues
Capabilities and limitations of modern imaging electromagnetic sensor systems are outlined, and the products of such systems are compared with those of the traditional aerial photographic system. Focus is given to the interface between the rapidly developing remote sensing technology and the information needs of operational agencies, and communication gaps are shown to retard early adoption of the technology by these agencies. An assessment is made of the current status of imaging remote sensors and their potential for the future. Public sources of remote sensor data and several cost comparisons are included
Organs from animals for man
In the following review some of the problems of xenotransplantation shall be discussed, based on the few experimental data available so far and on reports in the literature describing investigations which may be of importance for xenotransplantation. The impact of gravity on the upright posture of man versus almost all other mammals, the dysfunction between enzymes and hormones in different species and the lack of interactions between interleukins, cytokines and vasoactive substances will be taken into consideration. The question must be asked whether different levels of carrier molecules or serum proteins play a role in the physiological network. Even though the development of transgenic animals or other imaginative manipulations may lead to the acceptance of any type of xenografted organ, it has to be established for how long the products of the xenografts are able to act in the multifactorial orchestra. We are far from understanding xenogeneic molecular mechanisms involved in toxicity, necrosis and apoptosis or even reperfusion injury and ischemia in addition to the immediate mechanisms of the hyperacute xenogeneic rejection. Here, cell adhesion, blood clotting and vasomotion collide and bring micro-and macrocirculation to a standstill. All types of xenogeneic immunological mechanisms studied so far were found to have a more serious impact than those seen in allogeneic transplantation. In addition we are now only beginning to understand that so-called immunological parameters in allogeneic mechanisms act also in a true physiological manner in the xenogeneic situation. These molecular mechanisms occur behind the curtain of hyperacute, accelerated, acute or chronic xenograft rejection of which only some folds have been lifted to allow glimpses of part of the total scene. Other obstacles are likely to arise when long-term survival is achieved. These obstacles include retroviral infections, transfer of prions and severe side effects of the massive immunosuppression which will be needed. Moral, ethical and religious concerns are under debate and the species-specific production of proteins of the foreign donor species developed for clinical use suddenly appears to be a greater problem than anticipated
A Skylab program for the International Hydrological Decade (IHD)
There are no author-identified significant results in this report
Imaging Pauli repulsion in scanning tunneling microscopy
A scanning tunneling microscope (STM) has been equipped with a nanoscale
force sensor and signal transducer composed of a single D2 molecule that is
confined in the STM junction. The uncalibrated sensor is used to obtain
ultra-high geometric image resolution of a complex organic molecule adsorbed on
a noble metal surface. By means of conductance-distance spectroscopy and
corresponding density functional calculations the mechanism of the
sensor/transducer is identified. It probes the short-range Pauli repulsion and
converts this signal into variations of the junction conductance.Comment: 4 pages, 4 figures, accepted to Phys. Rev. Let
Experimental studies of hypersonic boundary-layer transition and effects of wind tunnel disturbances
Boundary layer transition data on cones and free stream disturbance levels were measured in a hypersonic wind tunnel and Mach 8 variable density hypersonic tunnel. Transition data were obtained by using different conical models and techniques for detecting the location of transition. The disturbance levels were measured by using hot wire anemometry and pressure transducers. The transition Reynolds numbers obtained from the tests correlated well when the fluctuating pressures measured at the surface of conical models were used as a correlating parameter
A foam model highlights the differences of the macro- and microrheology of respiratory horse mucus
Native horse mucus is characterized with micro- and macrorheology and
compared to hydroxyethylcellulose (HEC) gel as a model. Both systems show
comparable viscoelastic properties on the microscale and for the HEC the
macrorheology is in good agreement with the microrheology. For the mucus, the
viscoelastic moduli on the macroscale are several orders of magnitude larger
than on the microscale. Large amplitude oscillatory shear experiments show that
the mucus responds nonlinearly at much smaller deformations than HEC. This
behavior fosters the assumption that the mucus has a foam like structure on the
microscale compared to the typical mesh like structure of the HEC, a model that
is supported by cryogenic-scanning-electron-microscopy (CSEM) images. These
images allow also to determine the relative amount of volume that is occupied
by the pores and the scaffold. Consequently, we can estimate the elastic
modulus of the scaffold. We conclude that this particular foam like
microstructure should be considered as a key factor for the transport of
particulate matter which plays a central role in mucus function with respect to
particle penetration. The mesh properties composed of very different components
are responsible for macroscopic and microscopic behavior being part of
particles fate after landing.Comment: Accepted for publication in the Journal of the Mechanical Behavior of
Biomedical Material
Probing Pauli Blocking Factors in Quantum Pumps with Broken Time-Reversal Symmetry
A recently demonstrated quantum electron pump is discussed within the
framework of photon-assisted tunneling. Due to lack of time-reversal symmetry,
different results are obtained for the pump current depending on whether or not
final-state Pauli blocking factors are used when describing the tunneling
process. Whilst in both cases the current depends quadratically on the driving
amplitude for moderate pumping, a marked difference is predicted for the
temperature dependence. With blocking factors the pump current decreases
roughly linearly with temperature until k_B T ~ \hbar\omega is reached, whereas
without them it is unaffected by temperature, indicating that the entire Fermi
sea participates in the electronic transport.Comment: 4 pages in RevTex4 (beta4), 6 figures; status: to appear in PR
Reducing sample variance: halo biasing, non-linearity and stochasticity
Comparing clustering of differently biased tracers of the dark matter
distribution offers the opportunity to reduce the cosmic variance error in the
measurement of certain cosmological parameters. We develop a formalism that
includes bias non-linearities and stochasticity. Our formalism is general
enough that can be used to optimise survey design and tracers selection and
optimally split (or combine) tracers to minimise the error on the
cosmologically interesting quantities. Our approach generalises the one
presented by McDonald & Seljak (2009) of circumventing sample variance in the
measurement of . We analyse how the bias, the noise,
the non-linearity and stochasticity affect the measurements of and explore
in which signal-to-noise regime it is significantly advantageous to split a
galaxy sample in two differently-biased tracers. We use N-body simulations to
find realistic values for the parameters describing the bias properties of dark
matter haloes of different masses and their number density.
We find that, even if dark matter haloes could be used as tracers and
selected in an idealised way, for realistic haloes, the sample variance limit
can be reduced only by up to a factor .
This would still correspond to the gain from a three times larger survey volume
if the two tracers were not to be split. Before any practical application one
should bear in mind that these findings apply to dark matter haloes as tracers,
while realistic surveys would select galaxies: the galaxy-host halo relation is
likely to introduce extra stochasticity, which may reduce the gain further.Comment: 21 pages, 13 figures. Published version in MNRA
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