1,630 research outputs found

    Labour market performance of immigrants in the UK labour market

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    From executive summary: This document is a report commissioned by the Home Office to analyse the performance of immigrants in the UK labour market. It attempts to draw a comprehensive picture of the labour market performance of immigrants, and the process of adaptation relative to the UK-born white population. Four indicators of economic performance are investigated: (i) employment, (ii) labour force participation, (iii) self-employment, and (iv) wages. The analysis distinguishes between males and females, and between groups of different origin. The effects of specific variables on these outcomes are investigated in detail. The report also considers labour market outcomes of ethnic minority individuals who are born in the UK, and compares their outcomes with those of UK-born white individuals, and of ethnic minority individuals who are foreign-born

    Relative Properties of Smooth Terminating Bands

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    The relative properties of smooth terminating bands observed in the A~110 mass region are studied within the effective alignment approach. Theoretical values of ieffi_{eff} are calculated using the configuration-dependent shell-correction model with the cranked Nilsson potential. Reasonable agreement with experiment shows that previous interpretations of these bands are consistent with the present study. Contrary to the case of superdeformed bands, the effective alignments of these bands deviate significantly from the pure single-particle alignments of the corresponding orbitals. This indicates that in the case of smooth terminating bands, the effects associated with changes in equilibrium deformations contribute significantly to the effective alignment.Comment: 15 pages, 8 PostScript figures, RevTex, uses 'epsf', submitted to Nucl. Phys.

    Is the effect of birth weight on early breast cancer mediated through childhood growth?

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    Exposure–response modelling approaches for determining optimal dosing rules in children

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    Within paediatric populations, there may be distinct age groups characterised by different exposure–response relationships. Several regulatory guidance documents have suggested general age groupings. However, it is not clear whether these categorisations will be suitable for all new medicines and in all disease areas. We consider two model-based approaches to quantify how exposure–response model parameters vary over a continuum of ages: Bayesian penalised B-splines and model-based recursive partitioning. We propose an approach for deriving an optimal dosing rule given an estimate of how exposure–response model parameters vary with age. Methods are initially developed for a linear exposure–response model. We perform a simulation study to systematically evaluate how well the various approaches estimate linear exposure–response model parameters and the accuracy of recommended dosing rules. Simulation scenarios are motivated by an application to epilepsy drug development. Results suggest that both bootstrapped model-based recursive partitioning and Bayesian penalised B-splines can estimate underlying changes in linear exposure–response model parameters as well as (and in many scenarios, better than) a comparator linear model adjusting for a categorical age covariate with levels following International Conference on Harmonisation E11 groupings. Furthermore, the Bayesian penalised B-splines approach consistently estimates the intercept and slope more accurately than the bootstrapped model-based recursive partitioning. Finally, approaches are extended to estimate Emax exposure–response models and are illustrated with an example motivated by an in vitro study of cyclosporine

    Why immigration is no reason to leave the EU

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    EU immigration hasn't impacted employment or wages for the British people, write Jonathan Wadsworth, Swati Dhingra, Gianmarco Ottaviano and John Van Reene

    Immigration from the EU is not a ‘necessary evil’ and does not drag down wages

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    A major argument of the campaign to leave the EU is that Brexit would give the UK more control over the flow of immigrants from across Europe, who have supposedly hurt the jobs and pay of British workers. Research by Jonathan Wadsworth, Swati Dhingra, Gianmarco Ottaviano and John van Reenen shows that far from EU immigration being a ‘necessary evil’ to gain access to the greater trade and foreign investment that comes from being in the EU Single Market, immigration is at worst neutral and at best, an economic benefit of EU membership

    Do childhood cognitive ability or smoking behaviour explain the influence of lifetime socio-economic conditions on premature adult mortality in a British post war birth cohort?

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    Poor childhood and adult socio-economic conditions, lower childhood cognitive ability and cigarette smoking are all associated with adult mortality risk. Using data on 4458 men and women aged 60 years from a British birth cohort study, we investigated the extent to which these risk factors are part of the same pathway linking childhood experience to adult survival. Compared with women from non-manual origins, men from non-manual origins, women and men from manual origins, and those with missing data on father's social class had about double the risk of mortality between 26 and 60 years. Cox proportional hazards models showed that these differences were reduced but remained significant after adjusting for childhood cognitive ability, adult socio-economic conditions and smoking. Higher childhood ability increased survival chances by securing better adult socio-economic conditions, such as home ownership, which was strongly associated with survival. These findings were similar for cardiovascular and cancer mortality

    Very high rotational frequencies and band termination in 73Br

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    Rotational bands in 73Br have been investigated up to spins of 65/2 using the EUROBALL III spectrometer. One of the negative-parity bands displays the highest rotational frequency 1.85 MeV reported to date in nuclei with mass number greater than 25. At high frequencies, the experimental dynamic moment of inertia for all bands decrease to very low values, indicating a loss of collectivity. The bands are described in the configuration-dependent cranked Nilsson-Strutinsky model. The calculations indicate that one of the negative-parity bands is observed up to its terminating single-particle state at spin 63/2. This result establishes the first band termination case in the A = 70 mass region.Comment: 6 pages, 6 figures, submitted to Phys. Rev. C as a Rapid Communicatio
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