FDI in Space: Spatial Autoregressive Relationships in Foreign Direct Investment

Theoretical models of foreign direct investment (FDI) have only recently begun to model the role of third countries, and the empirical FDI literature has almost exclusively examined bilateral FDI data without recognizing the potential interdependence between FDI decisions to alternative host countries. This paper uses spatial econometric techniques to examine the spatial correlation between FDI to alternative (neighboring) regions. The sign of such correlations can provide evidence for or against alternative theories for FDI motivations. Using data on OECD countries from 1980-2000, we find evidence consistent with export platform FDI in Europe.

The role of the exit in the initial screening of investment opportunities: The case of business angel syndicate gatekeepers

The exit process has been largely ignored in business angel research.. The practitioner community identifies the difficulty in achieving exits as the most pressing problem for investors. This has been attributed to the failure of investors to adopt an exit-centric approach to investing. The validity of this claim is examined via a study of the investment approach of 21 ‘gatekeepers’ (managers) of angel groups in Scotland and Northern Ireland. Most gatekeepers say that they do consider the exit when they invest. However, this is contradicted by a verbal protocol analysis which indicates that the exit is not a significant consideration in their initial screening process. The small number of exits achieved by the groups is consistent with the general lack of an exit-centric approach to investing. Only three groups exhibit evidence of a strong exit-centric approach to investing. The lack of exits may have a negative impact on the level of future angel investment activity

Compilation of extended recursion in call-by-value functional languages

This paper formalizes and proves correct a compilation scheme for mutually-recursive definitions in call-by-value functional languages. This scheme supports a wider range of recursive definitions than previous methods. We formalize our technique as a translation scheme to a lambda-calculus featuring in-place update of memory blocks, and prove the translation to be correct.Comment: 62 pages, uses pi

WALLABY Pre-Pilot Survey: Radio Continuum Properties of the Eridanus Supergroup

We present the highest resolution and sensitivity $\sim1.4\,$GHz continuum observations of the Eridanus supergroup obtained as a part of the Widefield ASKAP L-band Legacy All-sky Blind surveY (WALLABY) pre-pilot observations using the Australian Square Kilometer Array Pathfinder (ASKAP). We detect 9461 sources at 1.37 GHz down to a flux density limit of $\sim0.1$ mJy at $6.1''\times 7.9''$ resolution with a mean root-mean-square (RMS) of 0.05 mJy/beam. We find that the flux scale is accurate to within 5% (compared to NVSS at 1.4 GHz). We then determine the global properties of eight Eridanus supergroup members, which are detected in both radio continuum and neutral hydrogen (HI) emission, and find that the radio-derived star formation rates (SFRs) agree well with previous literature. Using our global and resolved radio continuum properties of the nearby Eridanus galaxies, we measure and extend the infrared-radio correlation (IRRC) to lower stellar masses and inferred star formation rates than before. We find the resolved IRRC to be useful for: 1) discriminating between AGN and star-forming galaxies (SFGs); 2) identifying background radio sources; and 3) tracing the effects of group environment pre-processing in NGC 1385. We find evidence for tidal interactions and ram-pressure stripping in the HI, resolved spectral index and IRRC morphologies of NGC 1385. There appears to be a spatial coincidence (in projection) of double-lobed radio jets with the central HI hole of NGC 1367. The destruction of polycyclic aromatic hydrocarbons (PAHs) by merger-induced shocks may be driving the observed WISE W3 deficit observed in NGC 1359. Our results suggest that resolved radio continuum and IRRC studies are excellent tracers of the physical processes that drive galaxy evolution and will be possible on larger sample of sources with upcoming ASKAP radio continuum surveys.Comment: 26 pages, 14 figures, Accepted for publication at PASA 23/2/2023, Full catalogues and underlying data available at: https://doi.org/10.25919/8ga8-0n0

UK survey of occupational therapist’s and physiotherapist’s experiences and attitudes towards hip replacement precautions and equipment

Background: Total hip replacement (THR) is one of the most common orthopaedic procedures in the United Kingdom (UK). Historically, people following THR have been provided with hip precautions and equipment such as: raised toilet seats and furniture rises, in order to reduce the risks of dislocation post-operation. The purpose of this study was to determine current practices in the provision of these interventions in the UK for people following primary THR. Methods: A 27-question, self-administered online survey was developed and distributed to UK physiotherapists and occupational therapists involved in the management of people following primary THR (target respondents). The survey included questions regarding the current practices in the provision of equipment and hip precautions for THR patients, and physiotherapist’s and occupational therapist’s attitudes towards these practices. The survey was disseminated through print and web-based/social media channels. Results: 170 health professionals (87 physiotherapists and 83 occupational therapists), responded to the survey. Commonly prescribed equipment in respondent’s health trusts were raised toilet seats (95%), toilet frames and rails (88%), furniture raises (79%), helping hands/grabbers (77%), perching stools (75%) and long-handled shoe horns (75%). Hip precautions were routinely prescribed by 97% of respondents. Hip precautions were most frequently taught in a pre-operative group (52% of respondents). Similarly equipment was most frequently provided pre-operatively (61% respondents), and most commonly by occupational therapists (74% respondents). There was variability in the advice provided on the duration of hip precautions and equipment from up to six weeks post-operatively to life-time usage. Conclusions: Current practice on hip precautions and provision of equipment is not full representative of clinician’s perceptions of best care after THR. Future research is warranted to determine whether and to whom hip precautions and equipment should be prescribed post-THR as opposed to the current ‘blanket’ provision of equipment and movement restriction provided in UK practice

WALLABY Early Science – II. The NGC 7232 galaxy group

We report on neutral hydrogen (H I) observations of the NGC 7232 group with the Australian Square Kilometre Array Pathfinder (ASKAP). These observations were conducted as part of the Wide-field ASKAP L-Band Legacy All-sky Blind surveY (WALLABY) Early Science program with an array of 12 ASKAP antennas equipped with Phased Array Feeds, which were used to form 36 beams to map a field of view of 30 deg2. Analysing a subregion of the central beams, we detect 17 H I sources. Eleven of these detections are identified as galaxies and have stellar counterparts, of which five are newly resolved H I galaxy sources. The other six detections appear to be tidal debris in the form of H I clouds that are associated with the central triplet, NGC 7232/3, comprising the spiral galaxies NGC 7232, NGC 7232B, and NGC 7233. One of these H I clouds has a mass of MH I ∼ 3 × 108 M⊙ and could be the progenitor of a long-lived tidal dwarf galaxy. The remaining H I clouds are likely transient tidal knots that are possibly part of a diffuse tidal bridge between NGC 7232/3 and another group member, the lenticular galaxy IC 5181

Genomic catastrophes frequently arise in esophageal adenocarcinoma and drive tumorigenesis

Oesophageal adenocarcinoma (EAC) incidence is rapidly increasing in Western countries. A better understanding of EAC underpins efforts to improve early detection and treatment outcomes. While large EAC exome sequencing efforts to date have found recurrent loss-offunction mutations, oncogenic driving events have been underrepresented. Here we use a combination of whole-genome sequencing (WGS) and single-nucleotide polymorphism-array profiling to show that genomic catastrophes are frequent in EAC, with almost a third (32%, n¼40/123) undergoing chromothriptic events. WGS of 22 EAC cases show that catastrophes may lead to oncogene amplification through chromothripsis-derived double-minute chromosome formation (MYC and MDM2) or breakage-fusion-bridge (KRAS, MDM2 and RFC3). Telomere shortening is more prominent in EACs bearing localized complex rearrangements. Mutational signature analysis also confirms that extreme genomic instability in EAC can be driven by somatic BRCA2 mutations. These findings suggest that genomic catastrophes have a significant role in the malignant transformation of EAC