Hybrid entropy model of spatial data uncertainty in GIS

2006-2007 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe

Spatial analysis of urban economics in Guangdong Province

2013-2014 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe

A tracking algorithm of infrared sequence based on multi-model integration

2014-2015 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe

Research on the optimal path algorithm in multi-level road network

2006-2007 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe

Research on multi-resolution texture model in three-dimensional GIS

2002-2003 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe

Data uncertainties in geographic information system

2006-2007 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe

The further study on the accuracy of DEM terrain representation

2003-2004 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe

基于局部模糊方差的过渡区提取及图像分割

Author name used in this publication: 田岩Author name used in this publication: 刘继军Author name used in this publication: 谢玉波Author name used in this publication: SHI Wen-Zhong2007-2008 > Academic research: refereed > Publication in refereed journal202012 bcrcVersion of RecordPublishe

Landslide mapping from aerial photographs using change detection-based Markov random field

Landslide mapping (LM) is essential for hazard prevention, mitigation, and vulnerability assessment. Despite the great efforts over the past few years, there is room for improvement in its accuracy and efficiency. Existing LM is primarily achieved using field surveys or visual interpretation of remote sensing images. However, such methods are highly labor-intensive and time-consuming, particularly over large areas. Thus, in this paper a change detection-based Markov random field (CDMRF) method is proposed for near-automatic LM from aerial orthophotos. The proposed CDMRF is applied to a landslide-prone site with an area of approximately 40 km2 on Lantau Island, Hong Kong. Compared with the existing region-based level set evolution (RLSE), it has three main advantages: 1) it employs a more robust threshold method to generate the training samples; 2) it can identify landslides more accurately as it takes advantages of both the spectral and spatial contextual information of landslides; and 3) it needs little parameter tuning. Quantitative evaluation shows that it outperforms RLSE in the whole study area by almost 5.5% in Correctness and by 4% in Quality. To our knowledge, it is the first time CDMRF is used to LM from bitemporal aerial photographs. It is highly generic and has great potential for operational LM applications in large areas and also can be adapted for other sources of imagery data

Cyclic AMP-Dependent Protein Kinase A Regulates the Alternative Splicing of CaMKIIδ

Ca2+/calmodulin-dependent protein kinase (CaMK) IIδ is predominantly expressed in the heart. There are three isoforms of CaMKIIδ resulting from the alternative splicing of exons 14, 15, and 16 of its pre-mRNA, which is regulated by the splicing factor SF2/ASF. Inclusion of exons 15 and 16 or of exon 14 generates δA or δB isoform. The exclusion of all three exons gives rise to δC isoform, which is selectively increased in pressure-overload-induced hypertrophy. Overexpression of either δB or δC induces hypertrophy and heart failure, suggesting their specific role in the pathogenesis of hypertrophy and heart failure. It is well known that the β-adrenergic-cyclic AMP-dependent protein kinase A (PKA) pathway is implicated in heart failure. To determine the role of PKA in the alternative splicing of CaMKIIδ, we constructed mini-CaMKIIδ genes and used these genes to investigate the regulation of the alternative splicing of CaMKIIδ by PKA in cultured cells. We found that PKA promoted the exclusion of exons 14, 15, and 16 of CaMKIIδ, resulting in an increase in δC isoform. PKA interacted with and phosphorylated SF2/ASF, and enhanced SF2/ASF's activity to promote the exclusion of exons 14, 15, and 16 of CaMKIIδ, leading to a further increase in the expression of δC isoform. These findings suggest that abnormality in β-adrenergic-PKA signaling may contribute to cardiomyopathy and heart failure through dysregulation in the alternative splicing of CaMKIIδ exons 14, 15, and 16 and up-regulation of CaMKIIδC