1,782 research outputs found
Quantum Transport in the Presence of Random Traps
We calculate the asymptotic decay of a quantum particle moving in a d-dimensional medium doped with randomly placed trapping impurities, focusing on contributions from slowly decaying long-wavelength modes centered in large compact regions devoid of traps. By averaging the decay over the statistical distribution associated with these regions we find that the survival probability, P(t) ~exp(-Atd/(d+3)), decays more slowly in any dimension than for diffusive transport
The Nature and Frequency of the Gas Outbursts in Comet 67P/Churyumov-Gerasimenko observed by the Alice Far-ultraviolet Spectrograph on Rosetta
Alice is a far-ultraviolet imaging spectrograph onboard Rosetta that, amongst
multiple objectives, is designed to observe emissions from various atomic and
molecular species from within the coma of comet 67P/Churyumov-Gerasimenko. The
initial observations, made following orbit insertion in August 2014, showed
emissions of atomic hydrogen and oxygen spatially localized close to the
nucleus and attributed to photoelectron impact dissociation of H2O vapor.
Weaker emissions from atomic carbon were subsequently detected and also
attributed to electron impact dissociation, of CO2, the relative H I and C I
line intensities reflecting the variation of CO2 to H2O column abundance along
the line-of-sight through the coma. Beginning in mid-April 2015, Alice
sporadically observed a number of outbursts above the sunward limb
characterized by sudden increases in the atomic emissions, particularly the
semi-forbidden O I 1356 multiplet, over a period of 10-30 minutes, without a
corresponding enhancement in long wavelength solar reflected light
characteristic of dust production. A large increase in the brightness ratio O I
1356/O I 1304 suggests O2 as the principal source of the additional gas. These
outbursts do not correlate with any of the visible images of outbursts taken
with either OSIRIS or the navigation camera. Beginning in June 2015 the nature
of the Alice spectrum changed considerably with CO Fourth Positive band
emission observed continuously, varying with pointing but otherwise fairly
constant in time. However, CO does not appear to be a major driver of any of
the observed outbursts.Comment: 6 pages, 4 figures, accepted for publication in the Astrophysical
Journal Letter
Site of Accessory Pathway Block After Radiofrequency Catheter Ablation in Patients with the Wolff-Parkinson-White Syndrome
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/73717/1/j.1540-8167.1994.tb01111.x.pd
No evidence for basigin/CD147 as a direct SARS-CoV-2 spike binding receptor.
The spike protein of SARS-CoV-2 is known to enable viral invasion into human cells through direct binding to host receptors including ACE2. An alternate entry receptor for the virus was recently proposed to be basigin/CD147. These early studies have already prompted a clinical trial and multiple published hypotheses speculating on the role of this host receptor in viral infection and pathogenesis. Here, we report that we are unable to find evidence supporting the role of basigin as a putative spike binding receptor. Recombinant forms of the SARS-CoV-2 spike do not interact with basigin expressed on the surface of human cells, and by using specialized assays tailored to detect receptor interactions as weak or weaker than the proposed basigin-spike binding, we report no evidence for a direct interaction between the viral spike protein to either of the two common isoforms of basigin. Finally, removing basigin from the surface of human lung epithelial cells by CRISPR/Cas9 results in no change in their susceptibility to SARS-CoV-2 infection. Given the pressing need for clarity on which viral targets may lead to promising therapeutics, we present these findings to allow more informed decisions about the translational relevance of this putative mechanism in the race to understand and treat COVID-19
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