Wm. Johnson to Mr. Meredith (20 October 1962)

https://egrove.olemiss.edu/mercorr_pro/2182/thumbnail.jp

A structural equation analysis of the relationships between PTSD, depressive symptoms and suicidal ideation : is general strain theory a viable framework for explaining suicide risk among correctional staff?

There is a large body of evidence, which suggests PTSD is strongly related to increased suicide risk, however, some studies suggest the true nature of their relationship is better explained through the development of depression due to the effects of PTSD. While a majority of the studies examining this relationship focus only on general populations, a growing body research suggests that high-risk occupations such as police, firefighters and correctional staff are developing PTSD at rates as high as 8 to 10 times that of the rate of these general samples. This study, then, aims to fill a small gap in this nascent research into PTSD and suicide among high-risk occupations. Guided by a General Strain Theory framework, this study uses structural equation modeling to examine whether depression is capable of mediating the effect PTSD has on suicide risk. The results of this study support the use of GST as a viable framework for examining these relationships within high-risk samples, revealing depression mediated a negative direct relationship exhibited by PTSD on suicidal ideation. This suggests that while PTSD may still play a role in increased suicidal behavior, the main effect PTSD displays on increased suicidal thought is instead a product of the depression developed alongside other PTSD symptoms. These findings have implications for the treatment of PTSD and the handling of workplace-related trauma for individuals in high-risk occupations, especially correctional facilities

Interpretation of sensor data from in situ tests on a transversely bonded fibre-reinforced polymer road bridge

The Frampton Cotterell fibre-reinforced polymer road bridge deck comprises pultruded glass-fibre-reinforced polymer units which are laid longitudinally and are adhesively bonded transversely, in contrast to previous glass-fibre-reinforced polymer deck bridges where the pultruded units were laid transversely. This novel layout dictates that transverse distribution of live loading occurs only through the deck’s flanges and entails possible transverse tension which should be controlled to avoid cracks through the bonded deck–deck joints. This article assesses these structural actions by interpreting strains and deflections recorded during lorry testing of the bridge. Transverse distribution is evaluated by comparing transverse profiles of recorded longitudinal strains and of predicted longitudinal moments, with the conclusions qualitatively reinforced using a deflected surface based on the test recordings. Evidence of the deck acting as a continuum free of propagating joint cracks comes from the fact that the strains recorded during complementary lorry runs along the bridge satisfy the superposition principle and that the recorded strain influence lines replicate an idiosyncratic feature of the moment influence line without redistribution effects. That feature was then exploited to inform the strategy for a braking test which produced valuable vibration data for the bridge. Test data integrity is corroborated by cross checking deflections recorded from different types of sensors. It is concluded that since longitudinal placement of pultruded decks enhances the versatility of fibre-reinforced polymer bridges, this sensor layout and data interpretation process may form part of a wider strategy for health monitoring of such bridges

Enabling people, not completing tasks: patient perspectives on relationships and staff morale in mental health wards in England

BACKGROUND: Mental health inpatient wards are stressful places to work and concerns have been raised regarding quality of patient care and staff wellbeing on these wards. Recent research has suggested that robust support systems and conditions that allow staff to exercise professional autonomy in their clinical work result in better staff morale. Staff value having a voice in their organisations, and say that they would like more interaction with patients and processes to reduce violent incidents on wards. There has been little research into patients' views on staff morale and on how it may impact on their care. This study aimed to explore staff morale and staff-patient relationships from a patient perspective. METHODS: A qualitative investigation was conducted using purposive sampling to select seven inpatient wards in England representing various subspecialties. Semi-structured interviews were carried out with three patients on each ward. A thematic approach to analysis was used, supported by NVivo 10 software. RESULTS: Patients valued staff who worked together as a cohesive team, treated them as individuals, practised in a collaborative way and used enabling approaches to support their recovery. Participating patients described observing staff closely and feeling concerned at times about their well-being and the impact on them of stress and adverse incidents. They tended to perceive ward staff and patients as closely and reciprocally linked, with staff morale having a significant impact on patient well-being and vice versa. Some participants also described modifying their own behaviour because of concerns about staff well-being. Administrative duties, staff shortages and detrimental effects of violent incidents on the ward were seen as compromising staff members' ability to be involved with patients' lives and care. CONCLUSION: Patient views about the factors impacting on staff morale on inpatient wards are similar to those of staff in qualitative studies. Their accounts suggest that staff and patient morale should be seen as interlinked, suggesting there is scope for interventions to benefit both

Silver Song

https://digitalcommons.library.umaine.edu/mmb-vp/6581/thumbnail.jp

There\u27ll be a Rainbow in the Sky for You

https://digitalcommons.library.umaine.edu/mmb-vp/6370/thumbnail.jp

That Creepy Weepy Feeling

https://digitalcommons.library.umaine.edu/mmb-vp/6414/thumbnail.jp

Short-time photodissociation dynamics of A-band and B-band bromoiodomethane in solution: An examination of bond selective electronic excitation

We have obtained resonance, Raman spectra and absolute Raman cross section measurements at eight excitation wavelengths in the A-band and B-band absorptions of bromoiodomethane in cyclohexane solution. The resonance Raman intensities and absorption spectra were simulated using a simple model and time-dependent wave packet calculations. Normal mode vibrational descriptions were used with.the results of the calculations to find the short-time photodissociation dynamics in terms of internal coordinates. The A-band short-time photodissociation dynamics indicate that the C-I bond becomes much longer, the C-Br bond becomes smaller, the I-C-Br angle becomes smaller, the H-C-Br angles become larger, the H-C-I angles become smaller, and the H-C-H angle becomes a bit smaller. The B-band short-time photodissociation dynamics indicate the C-Br bond becomes much longer, the C-I bond becomes slightly longer, the I-C-Br angle becomes smaller, the H-C-I angles become larger, the H-C-Br angles become smaller, and the H-C-H angle becomes slightly smaller. Both the A-band and B-band short-time photodissociation dynamics appear to be most consistent with an impulsive "semi-rigid" radical model qualitative description of the photodissociation with the CH 2Br radical changing to a more planar structure in the A-band and the CH 2I radical changing to a more planar structure in the B band. We have carried out a Gaussian deconvolution of the A-band and B-band absorption spectra of bromoiodomethane, as well as iodomethane and bromomethane. The absorption spectra, resonance Raman intensities, and short-time photodissociation dynamics sueeest a moderate amount of coupling of the C-I and C-Br chromophores. © 1996 American Institute of Physics.published_or_final_versio

Fluid Convection, Generation and Reinfusion in Haemodiafiltration

Despite widespread use in clinical practice for over 30 years, many questions remain unanswered regarding fluid convection and reinfusion strategies in haemodiafiltration (HDF). Randomised controlled trials have failed to consistently demonstrate improved survival with convective therapies, but a dose-dependent improvement in outcome has been suggested. The ‘minimum’ and ‘ideal’ volumes of convection are undefined. Online generation of ultrapure dialysis fluid has allowed unprecedented convection volumes; however, delivery of fluid directly into the blood circuit requires strict monitoring. The replacement fluid may be reinfused at multiple points in the circuit. Post-dilution HDF is highly efficient in terms of solute clearance but is limited by haemoconcentration. Pre-dilution HDF prolongs filter life but requires significant convection volumes to achieve adequate solute clearance. Mid-dilution HDF utilises a specific dialyser, which is associated with additional cost and escalating transmembrane pressure. Mixed-dilution HDF appears to offer an attractive balance between solute clearance efficiency and haemoconcentration, however these findings need to be confirmed in large studies. The majority of trials comparing fluid reinfusion strategies have enrolled small numbers of patients over brief study periods. It is unclear whether high-quality evidence examining fluid convection and reinfusion will become available and practice may need to rely on observational data

Targeting the master regulator mTOR: A new approach to prevent the neurological of consequences of parasitic infections?

© 2017 The Author(s). A systematic analysis of 240 causes of death in 2013 revealed that parasitic diseases were responsible for more than one million deaths. The vast majority of these fatalities resulted from protozoan infections presenting with neurological sequelae. In the absence of a vaccine, development of effective therapies is essential to improving global public health. In 2015, an intriguing strategy to prevent cerebral malaria was proposed by Gordon et al. 2015 mBio, 6:e00625. Their study suggested that inhibition of the mammalian target of rapamycin prevented experimental cerebral malaria by blocking the damage to the blood brain barrier and stopping the accumulation of parasitized red blood cells and T cells in the brain. Here, we hypothesize that the same therapeutic strategy could be adopted for other protozoan infections with a brain tropism, to prevent cerebral parasitosis by limiting pathogen replication and preventing immune mediated destruction of brain tissue