Study of adhesion and cohesion in vacuum Final report

Vacuum metal-metal bonding tests to determine conditions of accidental adhesion of spacecraft structural material

Shifting Immigration Policies in Response to the Syrian Refugee Crisis Across the European Union: A Case Analysis of Germany, Hungary, and Lithuania

Over one million refugees have entered the borders of the European Union (EU) in 2015, forcing a discordant shift in the immigration policies of individual member states and upsetting the political stability of the region. This analysis answers the question of how immigration policies regarding asylum seekers in Germany, Hungary, and Lithuania specifically have changed recently and what these changes could indicate for the future of the European Union’s own immigration legislation. This research primarily paper analyzes asylum policy before the onset of the refugee crisis and evaluates how policy interests in the three different governments have developed in responses to the crisis. The approaches of each country towards immigration and asylum policy are distinct, and it is important to recognize these developments in order to understand the vulnerability of the Schengen Agreement as well as the future of EU solidarity. This research would fit to panels on the EU’s immigration and asylum policy, responses to the current refugee crisis, and the future of EU solidarity

Study of adhesion and cohesion in vacuum summary report 1 jul. 1963 - 30 jun. 1964

Adhesion and cohesion of metal couples in vacuum chambe

Hmga2 is dispensable for pancreatic cancer development, metastasis, and therapy resistance.

Expression of the chromatin-associated protein HMGA2 correlates with progression, metastasis and therapy resistance in pancreatic ductal adenocarcinoma (PDAC). Hmga2 has also been identified as a marker of a transient subpopulation of PDAC cells that has increased metastatic ability. Here, we characterize the requirement for Hmga2 during growth, dissemination, and metastasis of PDAC in vivo using conditional inactivation of Hmga2 in well-established autochthonous mouse models of PDAC. Overall survival, primary tumour burden, presence of disseminated tumour cells in the peritoneal cavity or circulating tumour cells in the blood, and presence and number of metastases were not significantly different between mice with Hmga2-wildtype or Hmga2-deficient tumours. Treatment of mice with Hmga2-wildtype and Hmga2-deficient tumours with gemcitabine did not uncover a significant impact of Hmga2-deficiency on gemcitabine sensitivity. Hmga1 and Hmga2 overlap in their expression in both human and murine PDAC, however knockdown of Hmga1 in Hmga2-deficient cancer cells also did not decrease metastatic ability. Thus, Hmga2 remains a prognostic marker which identifies a metastatic cancer cell state in primary PDAC, however Hmga2 has limited if any direct functional impact on PDAC progression and therapy resistance

Noncooperative algorithms in self-assembly

We show the first non-trivial positive algorithmic results (i.e. programs whose output is larger than their size), in a model of self-assembly that has so far resisted many attempts of formal analysis or programming: the planar non-cooperative variant of Winfree's abstract Tile Assembly Model. This model has been the center of several open problems and conjectures in the last fifteen years, and the first fully general results on its computational power were only proven recently (SODA 2014). These results, as well as ours, exemplify the intricate connections between computation and geometry that can occur in self-assembly. In this model, tiles can stick to an existing assembly as soon as one of their sides matches the existing assembly. This feature contrasts with the general cooperative model, where it can be required that tiles match on \emph{several} of their sides in order to bind. In order to describe our algorithms, we also introduce a generalization of regular expressions called Baggins expressions. Finally, we compare this model to other automata-theoretic models.Comment: A few bug fixes and typo correction

Cyclotrons as Drivers for Precision Neutrino Measurements

As we enter the age of precision measurement in neutrino physics, improved flux sources are required. These must have a well-defined flavor content with energies in ranges where backgrounds are low and cross section knowledge is high. Very few sources of neutrinos can meet these requirements. However, pion/muon and isotope decay-at-rest sources qualify. The ideal drivers for decay-at-rest sources are cyclotron accelerators, which are compact and relatively inexpensive. This paper describes a scheme to produce decay-at-rest sources driven by such cyclotrons, developed within the DAEdALUS program. Examples of the value of the high precision beams for pursuing Beyond Standard Model interactions are reviewed. New results on a combined DAEdALUS--Hyper-K search for CP-violation that achieve errors on the mixing matrix parameter of 4 degrees to 12 degrees are presented.Comment: This paper was invited by the journal Advances in High Energy Physics for their upcoming special issue on "Neutrino Masses and Oscillations," which will be published on the 100th anniversary of Pontecorvo's birt

SN 2008S: A Cool Super-Eddington Wind in a Supernova Impostor

We present visual-wavelength photometry and spectroscopy of supernova SN2008S. Based on the low peak luminosity for a SN of M_R = -13.9 mag, photometric and spectral evolution unlike that of low-luminosity SNe, a late-time decline rate slower than 56Co decay, and slow outflow speeds of 600-1000 km/s, we conclude that SN2008S is not a true core-collapse SN and is probably not an electron-capture SN. Instead, we show that SN2008S more closely resembles a "SN impostor" event like SN1997bs, analogous to the giant eruptions of LBVs. Its total radiated energy was 1e47.8 ergs, and it may have ejected 0.05-0.2 Msun in the event. We discover an uncanny similarity between the spectrum of SN 2008S and that of the Galactic hypergiant IRC+10420, which is dominated by narrow H-alpha, [Ca II], and Ca II emission lines formed in an opaque wind. We propose a scenario where the vastly super-Eddington wind of SN2008S partly fails because of reduced opacity due to recombination, as suggested for IRC+10420. The range of initial masses susceptible to eruptive LBV-like mass loss was known to extend down to 20-25 Msun, but estimates for the progenitor of SN2008S (and the similar NGC300 transient) may extend this range to around 15 Msun. As such, SN2008S may have implications for the progenitor of SN1987A.Comment: 4.5 pages, 2 figs, ApJ Letters accepted, figs and text significantly revised, fig1 in colo