81 research outputs found

    Lessons Learned About Societal Responses to Emerging Technologies Perceived as Risky

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    Presented at the 180-Minute Symposium Biofuels Ablaze, organized by Susan E Cozzens, Georgia Institute of Technology, Atlanta, GA.This presentation will present results from a research project that asks whether past experience in the United States with technologies associated in the public mind with risk, along with relevant social-scientific literatures, can inform strategies for bio-energy technologies.Research sponsored by the Program on Ethical, Legal, and Societal Implications (ELSI) of Research on Alternative Bioenergy Technologies, Synthetic Genomics, or Nanotechnologies, Office of Science, U.S. Department of Energ

    Understanding Climatic Impacts, Vulnerabilities, and Adaptation in the United States: Building a Capacity for Assessment

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    Based on the experience of the U.S. National Assessment, we propose a program of research and analysis to advance capability for assessment of climate impacts, vulnerabilities, and adaptation options. We identify specific priorities for scientific research on the responses of ecological and socioeconomic systems to climate and other stresses; for improvement in the climatic inputs to impact assessments; and for further development of assessment methods to improve their practical utility to decision-makers. Finally, we propose a new institutional model for assessment, based principally on regional efforts that integrate observations, research, data, applications, and assessment on climate and linked environmental-change issues. The proposed program will require effective collaboration between scientists, resource managers, and other stakeholders, all of whose expertise is needed to define and prioritize key regional issues, characterize relevant uncertainties, and assess potential responses. While both scientifically and organizationally challenging, such an integrated program holds the best promise of advancing our capacity to manage resources and the economy adaptively under a changing climate

    Lucro Real x Lucro Presumido: Opção menos onerosa para uma empresa prestadora de serviços de Comunicação.

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    TCC (Graduação) - Universidade Federal de Santa Catarina. Centro Socioeconômico. Curso de Ciências ContábeisCada vez mais o empresário visa o maior lucro para sua empresa, com a elevada carga tributária no Brasil é necessário que o empreendedor tenha um auxilio para a tomada de suas decisões no que diz respeito à tributação. Assim o profissional contábil tem papel importante na vida da empresa, fazendo um planejamento tributário, levando em consideração os benefícios que a opção correta do regime de tributação apresenta. Atualmente existem incentivos fiscais que podem ser utilizados como dedução dos impostos a pagar, a exemplo do PAT (Programa de Alimentação do Trabalhador), que permite a dedução direta de até 4% do imposto de renda a pagar, além de poder ser utilizado nos próximos dois anos de apuração o valor que ultrapassar este limite. O Lucro Presumido é uma forma mais simples de se apurar o imposto de renda, contribuição social sobre o lucro líquido, PIS e COFINS, pois parte de uma base presumida, o que facilita sua apuração para o contador. Já o Lucro Real é a forma mais complexa dos regimes de tributação, ele necessita de uma correta escrituração contábil para apurar os valores dos impostos a serem pagos, nesse regime a base de cálculo parte do lucro real da empresa, a partir da confrontação das receitas menos as despesas do período, podendo adicionar ou excluir dessa base as receitas e despesas previstas em lei. Para constatar a opção menos onerosa para a empresa em estudo, são apresentados os devidos cálculos para demonstrar ao empresário qual a opção menos onerosa para sua empresa ao se tratar dos regimes do Lucro Real e do Lucro Presumido

    Answering behavioral questions about energy efficiency in buildings

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    We identify behavioral questions that arise with 4 kinds of policy interventions for energy efficiency in buildings: information, incentives, standards, and technological research and development. A general strategy is described for answering such questions by using 6 analytical methods: formal models, analysis of existing data, surveys, ethnographic methods, small-scale experimentation, and evaluation research. We evaluate each method for addressing each behavioral question in policy analyses.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/26718/1/0000268.pd

    Transformational resilience thinking: Putting people, power and politics at the heart of urban climate resilience

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    Resilience is receiving substantial traction as a concept to inform climate change and development policies and programmes. At the same time, a number of critiques have emerged that question its use as a framing concept for tackling urban climate change. This paper reflects on climate resilience and its critiques through an examination of the Asian Cities Climate Change Resilience Network (ACCCRN) initiative in two cities in India. We illustrate aspects of the resilience critique and, using evidence of transformational aspects of the initiative, we argue that resilience thinking must be coupled with the concept of transformation in order to bring issues of people, politics and power to the fore. In the process, the conceptual strength of resilience can be combined with a more radical agenda that engages with underlying political structures and trade-offs that determine risk and vulnerability

    Intravascular Immune Surveillance by CXCR6(+) NKT Cells Patrolling Liver Sinusoids

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    We examined the in vivo behavior of liver natural killer T cells (NKT cells) by intravital fluorescence microscopic imaging of mice in which a green fluorescent protein cDNA was used to replace the gene encoding the chemokine receptor CXCR6. NKT cells, which account for most CXCR6(+) cells in liver, were found to crawl within hepatic sinusoids at 10–20 μm/min and to stop upon T cell antigen receptor activation. CXCR6-deficient mice exhibited a selective and severe reduction of CD1d-reactive NKT cells in the liver and decreased susceptibility to T-cell-dependent hepatitis. CXCL16, the cell surface ligand for CXCR6, is expressed on sinusoidal endothelial cells, and CXCR6 deficiency resulted in reduced survival, but not in altered speed or pattern of patrolling of NKT cells. Thus, NKT cells patrol liver sinusoids to provide intravascular immune surveillance, and CXCR6 contributes to liver-based immune responses by regulating their abundance
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