4 research outputs found
Magnetic configuration effects on the Wendelstein 7-X stellarator
The two leading concepts for confining high-temperature fusion plasmas are the tokamak and the stellarator. Tokamaks are rotationally symmetric and use a large plasma current to achieve confinement, whereas stellarators are non-axisymmetric and employ three-dimensionally shaped magnetic field coils to twist the field and confine the plasma. As a result, the magnetic field of a stellarator needs to be carefully designed to minimize the collisional transport arising from poorly confined particle orbits, which would otherwise cause excessive power losses at high plasma temperatures. In addition, this type of transport leads to the appearance of a net toroidal plasma current, the so-called bootstrap current. Here, we analyse results from the first experimental campaign of the Wendelstein 7-X stellarator, showing that its magnetic-field design allows good control of bootstrap currents and collisional transport. The energy confinement time is among the best ever achieved in stellarators, both in absolute figures (τE > 100 ms) and relative to the stellarator confinement scaling. The bootstrap current responds as predicted to changes in the magnetic mirror ratio. These initial experiments confirm several theoretically predicted properties of Wendelstein 7-X plasmas, and already indicate consistency with optimization measures
The same sequent variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm.
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70663.pdf (publisher's version ) (Closed access)Recently, two common sequence variants on 9p21, tagged by rs10757278-G and rs10811661-T, were reported to be associated with coronary artery disease (CAD) and type 2 diabetes (T2D), respectively. We proceeded to further investigate the contributions of these variants to arterial diseases and T2D. Here we report that rs10757278-G is associated with, in addition to CAD, abdominal aortic aneurysm (AAA; odds ratio (OR) = 1.31, P = 1.2 x 10(-12)) and intracranial aneurysm (OR = 1.29, P = 2.5 x 10(-6)), but not with T2D. This variant is the first to be described that affects the risk of AAA and intracranial aneurysm in many populations. The association of rs10811661-T to T2D replicates in our samples, but the variant does not associate with any of the five arterial diseases examined. These findings extend our insight into the role of the sequence variant tagged by rs10757278-G and show that it is not confined to atherosclerotic diseases