Model method drawing acts as a double-edged sword for solving inconsistent word problems

Drawing bar diagrams has been shown to improve performance on mathematical word problems wherein the relational keyword is consistent with the required arithmetic operation. This study extends this by testing the effectiveness of bar diagram drawing for word problems with an inconsistent keyword-arithmetic operation mapping. Seventy-five fifth graders solved consistent and inconsistent word problems while encouraged to draw bar diagrams. For each word problem, we assessed problem type (consistent/inconsistent), performance (correct/incorrect), and bar diagrams (accurate/inaccurate/no drawing). Overall, bar diagram drawing was associated with increased performance on both consistent and inconsistent word problems, but the strongest benefits of drawing were found for inconsistent word problems. For inconsistent word problems, bar diagram accuracy was more clearly related to performance (accurate bar diagrams related to correct answers, but inaccurate ones to incorrect answers) than for consistent word problems. We conclude that bar diagram drawing provides an effective graphical support for solving inconsistent word problems

Freezing controlled penetration of molten metals flowing through stainless steel tubes

The freezing controlled penetration potential of molten metals flowing within stainless steel structure is important to the safety assessment of hypothetical severe accidents in liquid metal reactors. A series of scoping experiments has been performed in which molten stainless steel and nickel at various initial temperatures and driving pressures were injected downward and upward into 6.4 and 3.3 mm ID stainless steel tubes filled with argon gas and initially at room temperature. In all tests, there was no evidence that the solid tube wall was wetted by the molten metals. The penetration phenomena are markedly different for downward versus upward injections. The dependency upon tube orientation is explained in terms of the absence of wetting. Complete plugs were formed in all experiments halting the continued injection of melt. Calculations with a fluid dynamics/heat transfer computer code show that the injected masses limited by plugging are consistent with freezing through the growth of a stable solidified layer (crust) of metal upon the solid tube wall. 23 refs., 5 figs., 2 tabs

Rapid and reproducible characterization of sickling during automated deoxygenation in sickle cell disease patients

In sickle cell disease (SCD), sickle hemoglobin (HbS) polymerizes upon deoxygenation, resulting in sickling of red blood cells (RBCs). These sickled RBCs have strongly reduced deformability, leading to vaso-occlusive crises and chronic hemolytic anemia. To date, there are no reliable laboratory parameters or assays capable of predicting disease severity or monitoring treatment effects. We here report on the oxygenscan, a newly developed method to measure RBC deformability (expressed as Elongation Index - EI) as a function of pO2. Upon a standardized, 22 minute, automated cycle of deoxygenation (pO2 median 16 mmHg ± 0.17) and reoxygenation, a number of clinically relevant parameters are produced in a highly reproducible manner (coefficients of variation <5%). In particular, physiological modulators of oxygen affinity, such as, pH and 2,3-diphosphoglycerate showed a significant correlation (respectively R = ‑0.993 and R = 0.980) with Point of Sickling (PoS5%), which is defined as the pO2 where a 5% decrease in EI is observed during deoxygenation. Furthermore, in vitro treatment with antisickling agents, including GBT440, which alter the oxygen affinity of hemoglobin, caused a reproducible left-shift of the PoS, indicating improved deformability at lower oxygen tensions. When RBCs from 21 SCD patients were analyzed, we observed a significantly higher PoS in untreated homozygous SCD patients compared to treated patients and other genotypes. We conclude that the oxygenscan is a state-of-the-art technique that allows for rapid analysis of sickling behavior in SCD patients. The method is promising for personalized treatment, development of new treatment strategies and could have potential in prediction of complications

Do we know what we test and do we test what we want to know?

Null hypothesis testing (NHT) is the most commonly used tool in empirical psychological research even though it has several known limitations. It is argued that since the hypotheses evaluated with NHT do not reflect the research-question or theory of the researchers, conclusions from NHT must be formulated with great modesty, that is, they cannot be stated in a confirmative way. Since confirmation or theory evaluation is, however, what researchers often aim for, we present an alternative approach that is based on the specification of explicit, informative statistical hypotheses. The statistical approach for the evaluation of these hypotheses is a Bayesian model-selection procedure. A non-technical explanation of the Bayesian approach is provided and it will be shown that results obtained with this method give more direct answers to the questions asked and are easier to interpret. An additional advantage of the offered possibility to formulate and evaluate informative hypotheses is that it stimulates researchers to more carefully think through and specify their expectations. © International Society for the Study of Behavioural Development 2011

On the capacity of network coding for random networks

We study the maximum flow possible between a single-source and multiple terminals in a weighted random graph (modeling a wired network) and a weighted random geometric graph (modeling an ad-hoc wireless network) using network coding. For the weighted random graph model, we show that the network coding capacity concentrates around the expected number of nearest neighbors of the source and the terminals. Specifically, for a network with a single source, l terminals, and n relay nodes such that the link capacities between any two nodes is independent and identically distributed (i.i.d.) similar to X, the maximum flow between the source and the terminals is approximately nE[X] with high probability. For the weighted random geometric graph model where two nodes are connected if they are within a certain distance of each other we show that with high probability the network coding capacity is greater than or equal to the expected number of nearest neighbors of the node with the least coverage area

Cultural conventions and the Virtual Learning Environment

Culture influences usability, and usability has influence on learning in a Virtual Learning Environment. When offering ‘e-Learning distance degree programs’ one has to take in account the cultural background of the student population. A mismatch between the culture for witch the Virtual Learning Environment was designed and the students can severely influence the students learning experience

Results of the GAP-4 experiment on molten-fuel drainage through intersubassembly gap geometry. [LMFBR]

One of the key issues in assessment of the meltout phase of a hypothetical core disruptive accident in the LMFBR system involves the timing and paths for dispersal of molten fuel from the disrupted core. A program of experiments is underway at Argonne National Laboratory to investigate molten fuel penetration through these postulated escape paths. The purpose of the GAP-4 test was to examine the penetration distances of molten fuel flowing through the flat, narrow channels representing the intersubassembly gap geometry. In the experiment design, the gap geometry was selected to be two-dimensional on the basis that the gap volume in a reactor design would be interconnected and continuous. The molten fuel used in these tests was a mixture of UO/sub 2/ (81%) and molybdenum (19%) which was generated by an exothermic thermite reaction at a temperature of approx. 3470 K