19,537 research outputs found
Surgical treatment of a paraspinal abscess with osteomyelitis and spinal cord compression in a rabbit
Array concepts for solid-state and vacuum microelectronics millimeter-wave generation
The authors have proposed that the increasing demand for contact watt-level coherent sources in the millimeter- and submillimeter-wave region can be satisfied by fabricating two-dimensional grids loaded with oscillators and multipliers for quasi-optical coherent spatial combining of the outputs of large numbers of low-power devices. This was first demonstrated through the successful fabrication of monolithic arrays with 2000 Schottky diodes. Watt-level power outputs were obtained in doubling to 66 GHz. In addition, a simple transmission-line model was verified with a quasi-optical reflectometer that measured the array impedance. This multiplier array work is being extended to novel tripler configurations using blocking barrier devices. The technique has also been extended to oscillator configurations where the grid structure is loaded with negative-resistance devices. This was first demonstrated using Gunn devices. More recently, a 25-element MESFET grid oscillating at 10 GHz exhibited power combining and self-locking. Currently, this approach is being extended to a 100-element monolithic array of Gunn diodes. This same approach should be applicable to planar vacuum electron devices such as the submillimeter-wave BWO (backward wave oscillator) and vacuum FET
Biased EPR entanglement and its application to teleportation
We consider pure continuous variable entanglement with non-equal correlations
between orthogonal quadratures. We introduce a simple protocol which equates
these correlations and in the process transforms the entanglement onto a state
with the minimum allowed number of photons. As an example we show that our
protocol transforms, through unitary local operations, a single squeezed beam
split on a beam splitter into the same entanglement that is produced when two
squeezed beams are mixed orthogonally. We demonstrate that this technique can
in principle facilitate perfect teleportation utilising only one squeezed beam.Comment: 8 pages, 5 figure
Systematic and Stochastic Variations in Pulsar Dispersion Measures
We analyze deterministic and random temporal variations in dispersion measure
(DM) from the full three-dimensional velocities of pulsars with respect to the
solar system, combined with electron-density variations on a wide range of
length scales. Previous treatments have largely ignored the pulsar's changing
distance while favoring interpretations involving the change in sky position
from transverse motion. Linear trends in pulsar DMs seen over 5-10~year
timescales may signify sizable DM gradients in the interstellar medium (ISM)
sampled by the changing direction of the line of sight to the pulsar. We show
that motions parallel to the line of sight can also account for linear trends,
for the apparent excess of DM variance over that extrapolated from
scintillation measurements, and for the apparent non-Kolmogorov scalings of DM
structure functions inferred in some cases. Pulsar motions through atomic gas
may produce bow-shock ionized gas that also contributes to DM variations. We
discuss possible causes of periodic or quasi-periodic changes in DM, including
seasonal changes in the ionosphere, annual variation of the solar elongation
angle, structure in the heliosphere-ISM boundary, and substructure in the ISM.
We assess the solar cycle's role on the amplitude of ionospheric and solar-wind
variations. Interstellar refraction can produce cyclic timing variations from
the error in transforming arrival times to the solar system barycenter. We
apply our methods to DM time series and DM gradient measurements in the
literature and assess consistency with a Kolmogorov medium. Finally, we discuss
the implications of DM modeling in precision pulsar timing experiments.Comment: 24 pages, 17 figures, published in Ap
Analysis of couch position tolerance limits to detect mistakes in patient setup
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/135643/1/acm20207.pd
The danger signal adenosine induces persistence of chlamydial infection through stimulation of A2b receptors
Infections with intracellular bacteria such as chlamydiae affect the majority of the world population. Infected tissue inflammation and granuloma formation help contain the short-term expansion of the invading pathogen, leading also to local tissue damage and hypoxia. However, the effects of key aspects of damaged inflamed tissues and hypoxia on continued infection with intracellular bacteria remain unknown. We find that development of Chlamydia trachomatis is reversibly retarded by prolonged exposure of infected cells to extracellular adenosine, a hallmark of hypoxia and advanced inflammation. In epithelial cells, this effect was mediated by the A2b adenosine receptor, unique in the adenosine receptor family for having a hypoxia-inducible factor (HIF1-α) binding site at its promoter region, and was dependent on an increase in the intracellular cAMP levels, but was independent of cAMP-dependent protein kinase (PKA). Further study of adenosine receptor signaling during intracellular bacterial infection could lead to breakthroughs in our understanding of persistent infections with these ubiquitous pathogens
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