Newtonian and Post-Newtonian approximations of the k = 0 Friedmann Robertson Walker Cosmology

In a previous paper we derived a post-Newtonian approximation to cosmology which, in contrast to former Newtonian and post-Newtonian cosmological theories, has a well-posed initial value problem. In this paper, this new post-Newtonian theory is compared with the fully general relativistic theory, in the context of the k = 0 Friedmann Robertson Walker cosmologies. It is found that the post-Newtonian theory reproduces the results of its general relativistic counterpart, whilst the Newtonian theory does not.Comment: 11 pages, Latex, corrected typo

On the Significance of the Weyl Curvature in a Relativistic Cosmological Model

The Weyl curvature includes the Newtonian field and an additional field, the so-called anti-Newtonian. In this paper, we use the Bianchi and Ricci identities to provide a set of constraints and propagations for the Weyl fields. The temporal evolutions of propagations manifest explicit solutions of gravitational waves. We see that models with purely Newtonian field are inconsistent with relativistic models and obstruct sounding solutions. Therefore, both fields are necessary for the nonlocal nature and radiative solutions of gravitation.Comment: 15 pages, incorporating proof correction

Cosmological Models with Shear and Rotation

Cosmological models involving shear and rotation are considered, first in the General Relat ivistic and then in the Newtonian framework with the aim of investigating singularities in them by using numerical and analytical techniques. The dynamics of these rotating models ar e studied. It is shown that singularities are unavoidable in such models and that the centr ifugal force arising due to rotation can never overcome the gravitational and shearing forc e over a length of time.Comment: 17 pages, 6 figures Journal Ref: J. Astrophys. Astr. (1999) 20, 79-8

Tachyonic potential in Bianchi type-I universe

Motivated from recent string theoretic results, a tachyonic potential is constructed for a spatially homogeneous and anisotropic background cosmology.Comment: 5 pages,LATEX,Typos in the text corrected, more references adde

Post-Newtonian extension of the Newton-Cartan theory

The theory obtained as a singular limit of General Relativity, if the reciprocal velocity of light is assumed to tend to zero, is known to be not exactly the Newton-Cartan theory, but a slight extension of this theory. It involves not only a Coriolis force field, which is natural in this theory (although not original Newtonian), but also a scalar field which governs the relation between Newtons time and relativistic proper time. Both fields are or can be reduced to harmonic functions, and must therefore be constants, if suitable global conditions are imposed. We assume this reduction of Newton-Cartan to Newton`s original theory as starting point and ask for a consistent post-Newtonian extension and for possible differences to usual post-Minkowskian approximation methods, as developed, for example, by Chandrasekhar. It is shown, that both post-Newtonian frameworks are formally equivalent, as far as the field equations and the equations of motion for a hydrodynamical fluid are concerned.Comment: 13 pages, LaTex, to appear in Class. Quantum Gra

Post-Newtonian Cosmology

Newtonian Cosmology is commonly used in astrophysical problems, because of its obvious simplicity when compared with general relativity. However it has inherent difficulties, the most obvious of which is the non-existence of a well-posed initial value problem. In this paper we investigate how far these problems are met by using the post-Newtonian approximation in cosmology.Comment: 12 pages, Late

A phase 3 multicenter, prospective, open-label efficacy and safety study of immune globulin (human) 10% caprylate/chromatography purified in patients with myasthenia gravis exacerbations

Background: Myasthenia gravis (MG) is an autoimmune disorder affecting neuromuscular transmission. Exacerbations may involve increasing bulbar weakness and/or sudden respiratory failure, both of which can be critically disabling. Management of MG exacerbations includes plasma exchange and intravenous immunoglobulin (IVIG); they are equally effective, but patients experience fewer side effects with IVIG. The objective of this study was to assess the efficacy and safety of immune globulin caprylate/chromatography purified (IGIV-C) in subjects with MG exacerbations. Methods: This prospective, open-label, non-controlled 28-day clinical trial was conducted in adults with MG Foundation of America class IVb or V status. Subjects received IGIV-C 2 g/kg over 2 consecutive days (1 g/kg/day) and were assessed for efficacy/safety on Days 7, 14, 21, and 28. The primary efficacy endpoint was the change from Baseline in quantitative MG (QMG) score to Day 14. Secondary endpoints of clinical response, Baseline to Day 14, included at least a 3-point decrease in QMG and MG Composite and a 2-point decrease in MG-activities of daily living (MG-ADL). Results: Forty-nine subjects enrolled. The change in QMG score at Day 14 was significant (p < 0.001) in the Evaluable (-6.4, n = 43) and Safety (-6.7, n = 49) populations. Among evaluable subjects, Day 14 response rates were 77, 86, and 88% for QMG, MG Composite, and MG-ADL, respectively. IGIV-C showed good tolerability with no serious adverse events. Conclusions: The results of this study show that IGIV-C was effective, safe, and well tolerated in the treatment of MG exacerbations

Anisotropy and inflation in Bianchi I brane worlds

After a more general assumption on the influence of the bulk on the brane, we extend some conclusions by Maartens et al. and Santos et al. on the asymptotic behavior of Bianchi I brane worlds. As a consequence of the nonlocal anisotropic stresses induced by the bulk, in most of our models, the brane does not isotropize and the nonlocal energy does not vanish in the limit in which the mean radius goes to infinity. We have also found the intriguing possibility that the inflation due to the cosmological constant might be prevented by the interaction with the bulk. We show that the problem for the mean radius can be completely solved in our models, which include as particular cases those in the references above.Comment: 10 pages, improved discussion on the likeliness of non-isotropization, completed list of references, matches version to appear in Class. Quantum Gra

CMB Anisotropy of Spherical Spaces

The first-year WMAP data taken at their face value hint that the Universe might be slightly positively curved and therefore necessarily finite, since all spherical (Clifford-Klein) space forms M^3 = S^3/Gamma, given by the quotient of S^3 by a group Gamma of covering transformations, possess this property. We examine the anisotropy of the cosmic microwave background (CMB) for all typical groups Gamma corresponding to homogeneous universes. The CMB angular power spectrum and the temperature correlation function are computed for the homogeneous spaces as a function of the total energy density parameter Omega_tot in the large range [1.01, 1.20] and are compared with the WMAP data. We find that out of the infinitely many homogeneous spaces only the three corresponding to the binary dihedral group T*, the binary octahedral group O*, and the binary icosahedral group I* are in agreement with the WMAP observations. Furthermore, if Omega_tot is restricted to the interval [1.00, 1.04], the space described by T* is excluded since it requires a value of Omega_tot which is probably too large being in the range [1.06, 1.07]. We thus conclude that there remain only the two homogeneous spherical spaces S^3/O* and S^3/I* with Omega_tot of about 1.038 and 1.018, respectively, as possible topologies for our Universe.Comment: A version with high resolution sky maps can be obtained at http://www.physik.uni-ulm.de/theo/qc