The nucleotide sequence of a human immnnoglobulin C-gamma-1 gene

We report the nucleotide sequence of a gene encoding the constant region of a human immnnoglobulin γ1 heavy chain (Cγ1). A comparison of this sequence with those of the Cγ2 and Cγ4 genes reveals that these three human Cγ genes share considerable homology in both coding and noncoding regions. The nucleotide sequence differences indicate that these genes diverged from one another approximately 6–8 million years ago. An examination of hinge exons shows that these coding regions have evolved more rapidly than any other areas of the Cγ genes in terms of both base substitution and deletion–insertion events. Coding sequence diversity also is observed in areas of CH domains which border the hinge

Quantum computers can search arbitrarily large databases by a single query

This paper shows that a quantum mechanical algorithm that can query information relating to multiple items of the database, can search a database in a single query (a query is defined as any question to the database to which the database has to return a (YES/NO) answer). A classical algorithm will be limited to the information theoretic bound of at least O(log N) queries (which it would achieve by using a binary search).Comment: Several enhancements to the original pape

Simple Proof of Security of the BB84 Quantum Key Distribution Protocol

We prove the security of the 1984 protocol of Bennett and Brassard (BB84) for quantum key distribution. We first give a key distribution protocol based on entanglement purification, which can be proven secure using methods from Lo and Chau's proof of security for a similar protocol. We then show that the security of this protocol implies the security of BB84. The entanglement-purification based protocol uses Calderbank-Shor-Steane (CSS) codes, and properties of these codes are used to remove the use of quantum computation from the Lo-Chau protocol.Comment: 5 pages, Latex, minor changes to improve clarity and fix typo

Irreversibility in asymptotic manipulations of entanglement

We show that the process of entanglement distillation is irreversible by showing that the entanglement cost of a bound entangled state is finite. Such irreversibility remains even if extra pure entanglement is loaned to assist the distillation process.Comment: RevTex, 3 pages, no figures Result on indistillability of PPT states under pure entanglement catalytic LOCC adde

Hexagonal ABCABC as semiconducting ferroelectrics

We use a first-principles rational-design approach to identify a previously-unrecognized class of ferroelectric materials in the $P63mc$ LiGaGe structure type. We calculate structural parameters, polarization and ferroelectric well depths both for reported and as-yet hypothetical representatives of this class. Our results provide guidance for the experimental realization and further investigation of high-performance materials suitable for practical applications.Comment: 5 pages, 2 figures, 3 table

Quantum State Disturbance vs. Information Gain: Uncertainty Relations for Quantum Information

When an observer wants to identify a quantum state, which is known to be one of a given set of non-orthogonal states, the act of observation causes a disturbance to that state. We investigate the tradeoff between the information gain and that disturbance. This issue has important applications in quantum cryptography. The optimal detection method, for a given tolerated disturbance, is explicitly found in the case of two equiprobable non-orthogonal pure states.Comment: 20 pages, standard LaTeX, four png figures (also available from the authors: [email protected] and [email protected]

On-demand single-photon state generation via nonlinear absorption

We propose a method for producing on-demand single-photon states based on collision-induced exchanges of photons and unbalanced linear absorption between two single-mode light fields. These two effects result in an effective nonlinear absorption of photons in one of the modes, which can lead to single photon states. A quantum nonlinear attenuator based on such a mechanism can absorb photons in a normal input light pulse and terminate the absorption at a single-photon state. Because the output light pulses containing single photons preserve the properties of the input pulses, we expect this method to be a means for building a highly controllable single photon source.Comment: 5 pages, 2 figures, to appear in PRA. To be published in PR

Using blubber explants to investigate adipose function in grey seals:glycolytic, lipolytic and gene expression responses to glucose and hydrocortisone

Adipose tissue is fundamental to energy balance, which underpins fitness and survival. Knowledge of adipose regulation in animals that undergo rapid fat deposition and mobilisation aids understanding of their energetic responses to rapid environmental change. Tissue explants can be used to investigate adipose regulation in wildlife species with large fat reserves, when opportunities for organismal experimental work are limited. We investigated glucose removal, lactate, glycerol and NEFA accumulation in media, and metabolic gene expression in blubber explants from wild grey seals. Glycolysis was higher in explants incubated in 25 mM glucose (HG) for 24 h compared to controls (C: 5.5 mM glucose). Adipose-derived lactate likely contributes to high endogenous glucose production in seals. Lipolysis was not stimulated by HG or high hydrocortisone (HC: 500 nM hydrocortisone) and was lower in heavier animals. HC caused NEFA accumulation in media to decrease by ~30% relative to C in females, indicative of increased lipogenesis. Lipolysis was higher in males than females in C and HG conditions. Lower relative abundance of 11-β-hydroxysteroid dehydrogenase 1 mRNA in HG explants suggests glucose involvement in blubber cortisol sensitivity. Our findings can help predict energy balance responses to stress and nutritional state in seals, and highlight the use of explants to study fat tissue function in wildlife

Quantum Channel Capacity of Very Noisy Channels

We present a family of additive quantum error-correcting codes whose capacities exceeds that of quantum random coding (hashing) for very noisy channels. These codes provide non-zero capacity in a depolarizing channel for fidelity parameters $f$ when $f> .80944$. Random coding has non-zero capacity only for $f>.81071$; by analogy to the classical Shannon coding limit, this value had previously been conjectured to be a lower bound. We use the method introduced by Shor and Smolin of concatenating a non-random (cat) code within a random code to obtain good codes. The cat code with block size five is shown to be optimal for single concatenation. The best known multiple-concatenated code we found has a block size of 25. We derive a general relation between the capacity attainable by these concatenation schemes and the coherent information of the inner code states.Comment: 31 pages including epsf postscript figures. Replaced to correct important typographical errors in equations 36, 37 and in tex