300 research outputs found
Enhancing the early student experience
This paper is concerned with identifying how the early student experience can be enhanced in order to improve levels of student retention and achievement. The early student experience is the focus of this project as the literature has consistently declared the first year to be the most critical in shaping persistence decisions. Programme managers of courses with high and low retention rates have been interviewed to identify activities that appear to be associated with good retention rates. The results show that there are similarities in the way programmes with high retention are run, with these features not being prevalent on programmes with low retention. Recommendations of activities that appear likely to enhance the early student experience are provided
Business Not as Usual: Developing Socially Conscious Entrepreneurs and Intrapreneurs
Our objective was to design an introductory business course to shape the mind-sets and skill sets of the next generation of socially conscious practitionersâto help students develop a sense of self-efficacy built on the confidence that they can make a positive impact on the world using entrepreneurial thinking and action. Essentially, the focus was to develop an introductory business course that would encourage and enable students to understand that business can be a force for good (sustainability and social impact) and to practice collaborative innovation (human-centered design thinking). The overarching design principle was business not as usual, which embraced four themes: (a) sustainability and social entrepreneurship, (b) collaborative innovation, (c) entrepreneurial thinking and action, and (d) self-authorship. We provide an overview of the course modules and their respective learning outcomes along with details of course content and activities to ensure transferability. A concluding discussion shares the impact on students and the challenges of success. We highlight how course design can be a catalyst to enable students to be the change they want to see in the world.Ye
Population genetics and gene variation in screwworms (Diptera: Calliphoridae) from Brazil
The International Consortium Investigating Neurocognition in Bipolar Disorder (ICONICĂą BD)
Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/148257/1/bdi12748.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/148257/2/bdi12748_am.pd
Terminal valuations, growth rates and the implied cost of capital
This article is published with open access at Springerlink.comWe develop a model based on the notion that prices lead earnings,
allowing for a simultaneous estimation of the implied growth rate and the cost of
equity capital for US industrial sectors. The major difference between our approach
and that in prior literature is that ours avoids the necessity to make assumptions
about terminal values and consequently about future growth rates. In fact, growth
rates are an endogenous variable, which is estimated simultaneously with the
implied cost of equity capital. Since we require only 1-year-ahead forecasts of
earnings and no assumptions about dividend payouts, our methodology allows us to
estimate ex ante aggregate growth and risk premia over a larger sample of firms than
has previously been possible. Our estimate of the risk premium being between 3.1
and 3.9 % is at the lower end of recent estimates, reflecting the inclusion of these
short-lived companies. Our estimate of the long run growth is from 4.2 to 4.7 %
Automatic Regulation of Hemodynamic Variables in Acute Heart Failure by a Multiple Adaptive Predictive Controller Based on Neural Networks
Lateral Canthotomy and Cantholysis: Emergency Management of Orbital Compartment Syndrome
Genome-Wide Association of Bipolar Disorder Suggests an Enrichment of Replicable Associations in Regions near Genes
Although a highly heritable and disabling disease, bipolar disorder's (BD) genetic variants have been challenging to identify. We present new genotype data for 1,190 cases and 401 controls and perform a genome-wide association study including additional samples for a total of 2,191 cases and 1,434 controls. We do not detect genome-wide significant associations for individual loci; however, across all SNPs, we show an association between the power to detect effects calculated from a previous genome-wide association study and evidence for replication (Pâ=â1.5Ă10â7). To demonstrate that this result is not likely to be a false positive, we analyze replication rates in a large meta-analysis of height and show that, in a large enough study, associations replicate as a function of power, approaching a linear relationship. Within BD, SNPs near exons exhibit a greater probability of replication, supporting an enrichment of reproducible associations near functional regions of genes. These results indicate that there is likely common genetic variation associated with BD near exons (±10 kb) that could be identified in larger studies and, further, provide a framework for assessing the potential for replication when combining results from multiple studies
A reference panel of 64,976 haplotypes for genotype imputation.
We describe a reference panel of 64,976 human haplotypes at 39,235,157 SNPs constructed using whole-genome sequence data from 20 studies of predominantly European ancestry. Using this resource leads to accurate genotype imputation at minor allele frequencies as low as 0.1% and a large increase in the number of SNPs tested in association studies, and it can help to discover and refine causal loci. We describe remote server resources that allow researchers to carry out imputation and phasing consistently and efficiently
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