96,785 research outputs found
Wind turbulence inputs for horizontal axis wind turbines
Wind turbine response characteristics in the presence of atmospheric turbulence was predicted using two major modeling steps. First, the important atmospheric sources for the force excitations felt by the wind turbine system were identified and characterized. Second, a dynamic model was developed which describes how these excitations are transmitted through the structure and power train. The first modeling step, that of quantifying the important excitations due to the atmospheric turbulence was established. The dynamic modeling of the second step was undertaken separately
Depolarization-activated potentiation of the T fiber synapse in the blue crab
The blue crab T fiber synapse, associated with the stretch receptor of the swimming leg, has a nonspiking presynaptic element that mediates tonic transmission. This synapse was isolated and a voltage clamp circuit was used to control the membrane potential at the release sites. The dependence of transmitter release on extracellular calcium, [Ca]o, was studied over a range of 2.5-40 mM. A power relationship of 2.7 was obtained between excitatory postsynaptic potential (EPSP) rate of rise and [Ca]o. Brief presynaptic depolarizing steps, 5-10 ms, presented at 0.5 Hz activated EPSP's of constant amplitude. Inserting a 300-ms pulse (conditioning pulse) between these test pulses potentiated the subsequent test EPSPs. This depolarization-activated potentiation (DAP) lasted for 10-20 s and decayed with a single exponential time course. The decay time course remained invariant with test pulse frequencies ranging from 0.11 to 1.1 Hz. The magnitude and decay time course of DAP were independent of the test pulse amplitudes. The magnitude of DAP was a function of conditioning pulse amplitudes. Large conditioning pulses activated large potentiations, whereas the decay time constants were not changed. The DAP is a Ca-dependent process. When the amplitude of conditioning pulses approached the Ca equilibrium potential, the magnitude of potentiation decreased. Repeated application of conditioning pulses, at 2-s intervals, did not produce additional potentiation beyond the level activated by the first conditioning pulse. Comparison of the conditioning EPSP waveforms activated repetitively indicated that potentiation lasted transiently, 100 ms, during a prolonged release. Possible mechanisms of the potentiation are discussed in light of these new findings.The blue crab T fiber synapse, associated with the stretch receptor of the swimming leg, has a nonspiking presynaptic element that mediates tonic transmission. This synapse was isolated and a voltage clamp circuit was used to control the membrane potential at the release sites. The dependence of transmitter release on extracellular calcium, [Ca]o, was studied over a range of 2.5-40 mM. A power relationship of 2.7 was obtained between excitatory postsynaptic potential (EPSP) rate of rise and [Ca]o. Brief presynaptic depolarizing steps, 5-10 ms, presented at 0.5 Hz activated EPSP's of constant amplitude. Inserting a 300-ms pulse (conditioning pulse) between these test pulses potentiated the subsequent test EPSPs. This depolarization-activated potentiation (DAP) lasted for 10-20 s and decayed with a single exponential time course. The decay time course remained invariant with test pulse frequencies ranging from 0.11 to 1.1 Hz. The magnitude and decay time course of DAP were independent of the test pulse amplitudes. The magnitude of DAP was a function of conditioning pulse amplitudes. Large conditioning pulses activated large potentiations, whereas the decay time constants were not changed. The DAP is a Ca-dependent process. When the amplitude of conditioning pulses approached the Ca equilibrium potential, the magnitude of potentiation decreased. Repeated application of conditioning pulses, at 2-s intervals, did not produce additional potentiation beyond the level activated by the first conditioning pulse. Comparison of the conditioning EPSP waveforms activated repetitively indicated that potentiation lasted transiently, 100 ms, during a prolonged release. Possible mechanisms of the potentiation are discussed in light of these new findings.NS-07942 - NINDS NIH HHS; NS-13742 - NINDS NIH HH
Tidal Barrier and the Asymptotic Mass of Proto Gas-Giant Planets
Extrasolar planets found with radial velocity surveys have masses ranging
from several Earth to several Jupiter masses. While mass accretion onto
protoplanetary cores in weak-line T-Tauri disks may eventually be quenched by a
global depletion of gas, such a mechanism is unlikely to have stalled the
growth of some known planetary systems which contain relatively low-mass and
close-in planets along with more massive and longer period companions. Here, we
suggest a potential solution for this conundrum. In general, supersonic infall
of surrounding gas onto a protoplanet is only possible interior to both of its
Bondi and Roche radii. At a critical mass, a protoplanet's Bondi and Roche
radii are equal to the disk thickness. Above this mass, the protoplanets' tidal
perturbation induces the formation of a gap. Although the disk gas may continue
to diffuse into the gap, the azimuthal flux across the protoplanets' Roche lobe
is quenched. Using two different schemes, we present the results of numerical
simulations and analysis to show that the accretion rate increases rapidly with
the ratio of the protoplanet's Roche to Bondi radii or equivalently to the disk
thickness. In regions with low geometric aspect ratios, gas accretion is
quenched with relatively low protoplanetary masses. This effect is important
for determining the gas-giant planets' mass function, the distribution of their
masses within multiple planet systems around solar type stars, and for
suppressing the emergence of gas-giants around low mass stars
Electron-hole symmetry and solutions of Richardson pairing model
Richardson approach provides an exact solution of the pairing Hamiltonian.
This Hamiltonian is characterized by the electron-hole pairing symmetry, which
is however hidden in Richardson equations. By analyzing this symmetry and using
an additional conjecture, fulfilled in solvable limits, we suggest a simple
expression of the ground state energy for an equally-spaced energy-level model,
which is applicable along the whole crossover from the superconducting state to
the pairing fluctuation regime. Solving Richardson equations numerically, we
demonstrate a good accuracy of our expression.Comment: 9 pages, 1 figure; accepted for publication in Eur. Phys. J.
Non-Thermal Production of WIMPs and the Sub-Galactic Structure of the Universe
There is increasing evidence that conventional cold dark matter (CDM) models
lead to conflicts between observations and numerical simulations of dark matter
halos on sub-galactic scales. Spergel and Steinhardt showed that if the CDM is
strongly self-interacting, then the conflicts disappear. However, the
assumption of strong self-interaction would rule out the favored candidates for
CDM, namely weakly interacting massive particles (WIMPs), such as the
neutralino. In this paper we propose a mechanism of non-thermal production of
WIMPs and study its implications on the power spectrum. We find that the
non-vanishing velocity of the WIMPs suppresses the power spectrum on small
scales compared to what it obtained in the conventional CDM model. Our results
show that, in this context, WIMPs as candidates for dark matter can work well
both on large scales and on sub-galactic scales.Comment: 6 pages, 2 figures; typo corrected; to appear in PR
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A hypothetical proposal for association between migraine and Meniere's disease.
Meniere's disease (MD) is a chronic condition affecting the inner ear whose precise etiology is currently unknown. We propose the hypothesis that MD is a migraine-related phenomenon which may have implications for future treatment options for both diseases. The association between MD and migraine is both an epidemiological and a mechanistic one, with up to 51% of individuals with MD experiencing migraine compared to 12% in the general population. The presence of endolymphatic hydrops in those with MD may be the factor that unites the two conditions, as hydropic inner ears have an impaired ability to maintain homeostasis. Migraine headaches are theorized to cause aura and symptoms via spreading cortical depression that ultimately results in substance P release, alterations in blood flow, and neurogenic inflammation. Chronically hydropic inner ears are less able to auto-regulate against the changes induced by active migraine attacks and may ultimately manifest as MD. This same vulnerability to derangements in homeostasis may also explain the common triggering factors of both MD attacks and migraine headaches, including stress, weather, and diet. Similarly, it may explain the efficacy of common treatments for both diseases: current migraine treatments such as anti-hypertensives and anti-convulsants have shown promise in managing MD. Though the etiology of both MD and migraine is likely multifactorial, further exploration of the association between the two conditions may illuminate how to best manage them in the future. MD is likely a manifestation of cochleovestibular migraine, which occurs as a result of migraine related changes in both the cochlea and vestibule
First Lattice Study of the - Transition Form Factors
Experiments at Jefferson Laboratory, MIT-Bates, LEGS, Mainz, Bonn, GRAAL, and
Spring-8 offer new opportunities to understand in detail how nucleon resonance
() properties emerge from the nonperturbative aspects of QCD. Preliminary
data from CLAS collaboration, which cover a large range of photon virtuality
show interesting behavior with respect to dependence: in the region
, both the transverse amplitude, , and the
longitudinal amplitude, , decrease rapidly. In this work, we
attempt to use first-principles lattice QCD (for the first time) to provide a
model-independent study of the Roper-nucleon transition form factor.Comment: 4 pages, 2 figures, double colum
Two-dimensional matrix algorithm using detrended fluctuation analysis to distinguish Burkitt and diffuse large B-cell lymphoma
Copyright © 2012 Rong-Guan Yeh et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.A detrended fluctuation analysis (DFA) method is applied to image analysis. The 2-dimensional (2D) DFA algorithms is proposed
for recharacterizing images of lymph sections. Due to Burkitt lymphoma (BL) and diffuse large B-cell lymphoma (DLBCL), there
is a significant different 5-year survival rates after multiagent chemotherapy. Therefore, distinguishing the difference between BL
and DLBCL is very important. In this study, eighteen BL images were classified as group A, which have one to five cytogenetic
changes. Ten BL images were classified as group B, which have more than five cytogenetic changes. Both groups A and B BLs are
aggressive lymphomas, which grow very fast and require more intensive chemotherapy. Finally, ten DLBCL images were classified
as group C. The short-term correlation exponent α1 values of DFA of groups A, B, and C were 0.370 ± 0.033, 0.382 ± 0.022, and
0.435 ± 0.053, respectively. It was found that α1 value of BL image was significantly lower (P < 0.05) than DLBCL. However, there
is no difference between the groups A and B BLs. Hence, it can be concluded that α1 value based on DFA statistics concept can
clearly distinguish BL and DLBCL image.National Science Council (NSC) of Taiwan the Center for Dynamical Biomarkers and
Translational Medicine, National Central University, Taiwan (also sponsored by National Science Council)
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