Structure-Induced Reversible Anionic Redox Activity in Na Layered Oxide Cathode

Anionic redox reaction (ARR) in lithium- and sodium-ion batteries is under hot discussion, mainly regarding how oxygen anion participates and to what extent oxygen can be reversibly oxidized and reduced. Here, a P3-type Na0.6[Li0.2Mn0.8]O2 with reversible capacity from pure ARR was studied. The interlayer O-O distance (peroxo-like O-O dimer, 2.506(3) Å), associated with oxidization of oxygen anions, was directly detected by using a neutron total scattering technique. Different from Li2RuO3 or Li2IrO3 with strong metal-oxygen (M-O) bonding, for P3-type Na0.6[Li0.2Mn0.8]O2 with relatively weak Mn-O covalent bonding, crystal structure factors might play an even more important role in stabilizing the oxidized species, as both Li and Mn ions are immobile in the structure and thus may inhibit the irreversible transformation of the oxidized species to O2 gas. Utilization of anionic redox reaction (ARR) on oxygen has been considered as an effective way to promote the charge-discharge capacity of the layered oxide cathodes for lithium- or sodium-ion batteries. The detailed mechanism of ARR, in particular how crystal structure affects and coordinates with the ARR, is not yet well understood. In the present work, a combination of X-ray and neutron total scattering measurements has been performed to study the structure of the prototype P3-type layered Na0.6[Li0.2Mn0.8]O2 with pure ARR. Unique structural characteristics, rather than prevailing knowledge of covalency of metal-oxygen, enable the stabilization of the crystal structure of Na0.6[Li0.2Mn0.8]O2 along with the ARR. This work suggests that reversible ARR can be manipulated by proper structure designs, thus to achieve high lithium or sodium storage in layered oxide cathodes. For P3-type Na0.6[Li0.2Mn0.8]O2 with relatively weak Mn-O covalent bonding, crystal structure factors play an important role in stabilizing the oxidized species, inhibiting the irreversible transformation of the oxidized species to O2 gas. The finding is important for better design of layered oxide positive materials with higher reversible capacity via the introduction of a reversible anionic redox reaction

Topological Aspect of Knotted Vortex Filaments in Excitable Media

Scroll waves exist ubiquitously in three-dimensional excitable media. It's rotation center can be regarded as a topological object called vortex filament. In three-dimensional space, the vortex filaments usually form closed loops, and even linked and knotted. In this letter, we give a rigorous topological description of knotted vortex filaments. By using the $\phi$-mapping topological current theory, we rewrite the topological current form of the charge density of vortex filaments and use this topological current we reveal that the Hopf invariant of vortex filaments is just the sum of the linking and self-linking numbers of the knotted vortex filaments. We think that the precise expression of the Hopf invariant may imply a new topological constraint on knotted vortex filaments.Comment: 4 pages, no figures, Accepted by Chin. Phys. Let

Calibrating E-values for MS2 database search methods

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Detection of co-eluted peptides using database search methods

<p>Abstract</p> <p>Background</p> <p>Current experimental techniques, especially those applying liquid chromatography mass spectrometry, have made high-throughput proteomic studies possible. The increase in throughput however also raises concerns on the accuracy of identification or quantification. Most experimental procedures select in a given MS scan only a few relatively most intense parent ions, each to be fragmented (MS²) separately, and most other minor co-eluted peptides that have similar chromatographic retention times are ignored and their information lost.</p> <p>Results</p> <p>We have computationally investigated the possibility of enhancing the information retrieval during a given LC/MS experiment by selecting the two or three most intense parent ions for simultaneous fragmentation. A set of spectra is created via superimposing a number of MS²spectra, each can be identified by all search methods tested with high confidence, to mimick the spectra of co-eluted peptides. The generated convoluted spectra were used to evaluate the capability of several database search methods – SEQUEST, Mascot, X!Tandem, OMSSA, and RAId_DbS – in identifying true peptides from superimposed spectra of co-eluted peptides. We show that using these simulated spectra, all the database search methods will gain eventually in the number of true peptides identified by using the compound spectra of co-eluted peptides.</p> <p>Open peer review</p> <p>Reviewed by Vlad Petyuk (nominated by Arcady Mushegian), King Jordan and Shamil Sunyaev. For the full reviews, please go to the Reviewers' comments section.</p

Relation between millimeter wavelengths emission and high-energy emission for active galactic nuclei

After comparing the flux densities of a sample of active galactic nuclei detected by energetic gamma-ray experiment telescope at 90 and 230 GHz with the $\gamma$-ray emissions detected by Compton Gamma Ray Observatory and x-ray emission, a strong correlation between the emissions at the millimeter wavelength and the $\gamma$-ray emission is found. The average flux density of x-ray is almost proportional to the average flux density at the millimeter wavelength for quasars detected by energetic gamma-ray experiment telescope, which strongly supports the previous idea that the x-ray emissions of this kind sources are mainly produced by Synchrotron Self-Compton process.Comment: 6 pages, Chinese Physics Letters in pres

Experimentally obtaining the Likeness of Two Unknown Quantum States on an NMR Quantum Information Processor

Recently quantum states discrimination has been frequently studied. In this paper we study them from the other way round, the likeness of two quantum states. The fidelity is used to describe the likeness of two quantum states. Then we presented a scheme to obtain the fidelity of two unknown qubits directly from the integral area of the spectra of the assistant qubit(spin) on an NMR Quantum Information Processor. Finally we demonstrated the scheme on a three-qubit quantum information processor. The experimental data are consistent with the theoretical expectation with an average error of 0.05, which confirms the scheme.Comment: 3 pages, 4 figure

Population transcriptomes reveal synergistic responses of DNA polymorphism and RNA expression to extreme environments on the Qinghai-Tibetan Plateau in a predatory bird

Low oxygen and temperature pose key physiological challenges for endotherms living on the Qinghai–Tibetan Plateau (QTP). Molecular adaptations to high‐altitude living have been detected in the genomes of Tibetans, their domesticated animals and a few wild species, but the contribution of transcriptional variation to altitudinal adaptation remains to be determined. Here we studied a top QTP predator, the saker falcon, and analysed how the transcriptome has become modified to cope with the stresses of hypoxia and hypothermia. Using a hierarchical design to study saker populations inhabiting grassland, steppe/desert and highland across Eurasia, we found that the QTP population is already distinct despite having colonized the Plateau <2000 years ago. Selection signals are limited at the cDNA level, but of only seventeen genes identified, three function in hypoxia and four in immune response. Our results show a significant role for RNA transcription: 50% of upregulated transcription factors were related to hypoxia responses, differentiated modules were significantly enriched for oxygen transport, and importantly, divergent EPAS1 functional variants with a refined co‐expression network were identified. Conservative gene expression and relaxed immune gene variation may further reflect adaptation to hypothermia. Our results exemplify synergistic responses between DNA polymorphism and RNA expression diversity in coping with common stresses, underpinning the successful rapid colonization of a top predator onto the QTP. Importantly, molecular mechanisms underpinning highland adaptation involve relatively few genes, but are nonetheless more complex than previously thought and involve fine‐tuned transcriptional responses and genomic adaptation

Deconfined quantum criticality and emergent symmetry in SrCu2(BO3)2

The deconfined quantum critical point (DQCP) represents a paradigm shift in theories of quantum matter, presenting a "beyond Landau" scenario for order-order transitions. Its experimental realization, however, has remained elusive. Here we demonstrate by high-pressure 11B NMR measurements on the quantum magnet SrCu2(BO3)2 that the magnetic field induced plaquette-singlet to antiferromagnetic transition above 1.8 GPa is proximate to a DQCP. We find a weak first-order transition between the two phases at a remarkably low temperature, Tc~0.07 K. Above Tc we observe quantum critical scaling at the highest pressure, 2.4 GPa. We explain the low first-order Tc values by a DQCP-induced emergent O(3) symmetry that is broken in the coexistence state. Our findings take the DQCP from a theoretical concept to a concrete experimental platform

Human Polyclonal Antibodies Produced from Transchromosomal Bovine Provides Prophylactic and Therapeutic Protections Against Zika Virus Infection in STAT2 KO Syrian Hamsters

Zika virus (ZIKV) infection can cause severe congenital diseases, such as microcephaly, ocular defects and arthrogryposis in fetuses, and Guillain–Barré syndrome in adults. Efficacious therapeutic treatments for infected patients, as well as prophylactic treatments to prevent new infections are needed for combating ZIKV infection. Here, we report that ZIKV-specific human polyclonal antibodies (SAB-155), elicited in transchromosomal bovine (TcB), provide significant protection from infection by ZIKV in STAT2 knockout (KO) golden Syrian hamsters both prophylactically and therapeutically. These antibodies also prevent testicular lesions in this hamster model. Our data indicate that antibody-mediated immunotherapy is effective in treating ZIKV infection. Because suitable quantities of highly potent human polyclonal antibodies can be quickly produced from the TcB system against ZIKV and have demonstrated therapeutic efficacy in a small animal model, they have the potential as an effective countermeasure against ZIKV infection

Long-Term Smart Grid Planning Under Uncertainty Considering Reliability Indexes

The electricity sector is fast moving towards a new era of clean generation devices dispersed along the network. On one hand, this will largely contribute to achieve the multi-national environment goals agreed via political means. On the other hand, network operators face new complexities and challenges regarding network planning due to the large uncertainties associated with renewable generation and electric vehicles integration. In addition, due to new technologies such as combined heat and power (CHP), the district heat demand is considered in the long-term planning problem. The 13-bus medium voltage network is evaluated considering the possibility of CHP units but also without. Results demonstrate that CHP, together with heat-only boiler units, can supply the district heat demand and contribute to network reliability. They can also reduce the expected energy not supplied and the power losses cost, avoiding the need to invest in new power lines for the considered lifetime project.This work has received funding from the EU's Horizon 2020 research and innovation programme under the Marie Sklodowska-Curie grant agreement No 641794 (project DREAM-GO) and from FEDER Funds through COMPETE program and from National Funds through FCT under the project UID/EEA/00760/2013. Bruno Canizes is supported by FCT Funds through SFRH/BD/110678/2015 PhD scholarship and M. Ali Fotouhi Ghazvini is supported by FCT Funds through SFRH/BD/94688/2013 PhD scholarship.info:eu-repo/semantics/publishedVersio