294 research outputs found

    Exactly solvable potentials of Calogero type for q-deformed Coxeter groups

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    We establish that by parameterizing the configuration space of a one-dimensional quantum system by polynomial invariants of q-deformed Coxeter groups it is possible to construct exactly solvable models of Calogero type. We adopt the previously introduced notion of solvability which consists of relating the Hamiltonian to finite dimensional representation spaces of a Lie algebra. We present explicitly the G2qG_2^q -case for which we construct the potentials by means of suitable gauge transformations.Comment: 22 pages Late

    Quantum Calogero-Moser Models: Integrability for all Root Systems

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    The issues related to the integrability of quantum Calogero-Moser models based on any root systems are addressed. For the models with degenerate potentials, i.e. the rational with/without the harmonic confining force, the hyperbolic and the trigonometric, we demonstrate the following for all the root systems: (i) Construction of a complete set of quantum conserved quantities in terms of a total sum of the Lax matrix (L), i.e. (\sum_{\mu,\nu\in{\cal R}}(L^n)_{\mu\nu}), in which ({\cal R}) is a representation space of the Coxeter group. (ii) Proof of Liouville integrability. (iii) Triangularity of the quantum Hamiltonian and the entire discrete spectrum. Generalised Jack polynomials are defined for all root systems as unique eigenfunctions of the Hamiltonian. (iv) Equivalence of the Lax operator and the Dunkl operator. (v) Algebraic construction of all excited states in terms of creation operators. These are mainly generalisations of the results known for the models based on the (A) series, i.e. (su(N)) type, root systems.Comment: 45 pages, LaTeX2e, no figure

    Pharmacokinetics of oxycodone/naloxone and its metabolites in patients with end-stage renal disease during and between haemodialysis sessions

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    The pharmacokinetics of oxycodone in patients with end-stage renal disease (ESRD) requiring haemodialysis are largely unknown. Therefore, we investigated the pharmacokinetics of oxycodone/naloxone prolonged release and their metabolites in patients with ESRD during and between haemodialysis sessions.; Single doses of oxycodone/naloxone (5/2.5 or 10/5 mg) were administered in nine patients with ESRD using a cross-over design on the day of dialysis and on a day between dialysis sessions. Plasma, dialysate and urine concentrations of oxycodone, naloxone and their metabolites were determined up to 48 h post-dosing using a liquid chromatography-tandem mass spectrometry system.; Haemodialysis performed 6-10 h after dosing removed ∌10% of the administered dose of oxycodone predominantly as unconjugated oxycodone and noroxycodone or conjugated oxymorphone and noroxymorphone. The haemodialysis clearance of oxycodone based on its recovery in dialysate was (mean ± SD) 8.4 ± 2.1 L/h. The geometric mean (coefficient of variation) plasma elimination half-life of oxycodone during the 4-h haemodialysis period was 3.9 h (39%) which was significantly shorter than the 5.7 h (22%) without haemodialysis. Plasma levels of the active metabolite oxymorphone in its unconjugated form were very low.; Oxycodone is removed during haemodialysis. The pharmacokinetics including the relatively short half-life of oxycodone in patients with ESRD with or without haemodialysis and the absence of unconjugated active metabolites indicate that oxycodone can be used at usual doses in patients requiring dialysis

    Young and Intermediate-age Distance Indicators

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    Distance measurements beyond geometrical and semi-geometrical methods, rely mainly on standard candles. As the name suggests, these objects have known luminosities by virtue of their intrinsic proprieties and play a major role in our understanding of modern cosmology. The main caveats associated with standard candles are their absolute calibration, contamination of the sample from other sources and systematic uncertainties. The absolute calibration mainly depends on their chemical composition and age. To understand the impact of these effects on the distance scale, it is essential to develop methods based on different sample of standard candles. Here we review the fundamental properties of young and intermediate-age distance indicators such as Cepheids, Mira variables and Red Clump stars and the recent developments in their application as distance indicators.Comment: Review article, 63 pages (28 figures), Accepted for publication in Space Science Reviews (Chapter 3 of a special collection resulting from the May 2016 ISSI-BJ workshop on Astronomical Distance Determination in the Space Age
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