Gonococcal osteomyelitis in a pediatric patient with disseminated gonococcal infection: Implications for antimicrobial management

© 2020 The Authors We report a case of a female teenager with gonococcal septic arthritis of the right shoulder that also caused osteomyelitis of the humeral head. Infection with Neisseria gonorrhoeae is a frequently diagnosed sexually transmitted infection in the sexually active teenage population and disseminated gonococcal infection (DGI) is the most common systemic manifestation of acute gonorrhea. DGI commonly involves acute arthritis, tenosynovitis and dermatitis with less common complications of endocarditis, hepatitis and meningitis. In contrast, osteomyelitis has only rarely been reported as a result of gonococcal infection. Clinicians need to be aware of this unusual manifestation of DGI as a prolonged duration of antimicrobial treatment may be needed to assure complete resolution of this infection

Far-off-resonant wave interaction in one-dimensional photonic crystals with quadratic nonlinearity

We extend a recently developed Hamiltonian formalism for nonlinear wave interaction processes in spatially periodic dielectric structures to the far-off-resonant regime, and investigate numerically the three-wave resonance conditions in a one-dimensional optical medium with $\chi^{(2)}$ nonlinearity. In particular, we demonstrate that the cascading of nonresonant wave interaction processes generates an effective $\chi^{(3)}$ nonlinear response in these systems. We obtain the corresponding coupling coefficients through appropriate normal form transformations that formally lead to the Zakharov equation for spatially periodic optical media.Comment: 14 pages, 4 figure

Evaluation of the vaginal flora in pregnant women receiving opioid maintenance therapy: a matched case-control study

Dataset supporting the conclusions of this article. (XLS 2634 kb

A Re-evaluation of Evidence for Light Neutral Bosons in Nuclear Emulsions

Electron-positron pair-production data obtained by bombardment of emulsion detectors with either cosmic rays or projectiles with mass between one and 207 and kinetic energies between 18 GeV and 32 TeV have been re-analysed using a consistent and conservative model of the background from electromagnetic pair conversion. The combined data yield a spectrum of putative neutral bosons decaying to e+e- pairs, with masses between 3 and 20 MeV/c^2 and femtosecond lifetimes. The statistical significance against background for these "X-bosons" varies between 2 and 8 sigma. The cross-section for direct production of X-bosons increases slowly with projectile energy, remaining over 1,000 times smaller the the pion production cross-section.Comment: major revision with improved figures; accepted by Int J Mod Phys

Studies of the motion and decay of axion walls bounded by strings

We discuss the appearance at the QCD phase transition, and the subsequent decay, of axion walls bounded by strings in N=1 axion models. We argue on intuitive grounds that the main decay mechanism is into barely relativistic axions. We present numerical simulations of the decay process. In these simulations, the decay happens immediately, in a time scale of order the light travel time, and the average energy of the radiated axions is $\simeq 7 m_a$ for $v_a/m_a \simeq 500$. $$ is found to increase approximately linearly with $\ln(v_a/m_a)$. Extrapolation of this behaviour yields $\sim 60 m_a$ in axion models of interest. We find that the contribution to the cosmological energy density of axions from wall decay is of the same order of magnitude as that from vacuum realignment, with however large uncertainties. The velocity dispersion of axions from wall decay is found to be larger, by a factor $10^3$ or so, than that of axions from vacuum realignment and string decay. We discuss the implications of this for the formation and evolution of axion miniclusters and for the direct detection of axion dark matter on Earth. Finally we discuss the cosmology of axion models with $N>1$ in which the domain wall problem is solved by introducing a small U$_{PQ}$(1) breaking interaction. We find that in this case the walls decay into gravitational waves.Comment: 37 pages, 10 figures, a minor mistake was corrected, several references and comments were adde