Simultaneous dual-species laser cooling using an optical frequency comb

We demonstrate 1D simultaneous laser cooling of $^{87}$Rb and $^{85}$Rb atoms using an optical frequency comb. By adjusting the pulse repetition frequency and the offset frequency, the frequency comb spectrum is tuned to ensure that two distinct frequency comb modes are simultaneously red-detuned from the cooling transitions, one mode for each species. Starting from a pre-cooled cloud of $^{85,87}$Rb atoms at above-Doppler temperatures, we show simultaneous cooling of both species down to the Doppler temperature using two counter-propagating $\sigma$$^{+}$/$\sigma$$^{-}$-polarized beams from the frequency comb. The results indicate that simultaneous dual-species frequency comb cooling does not affect the cooling characteristics of individual atomic species. The results of this work imply that several atomic species could be cooled simultaneously using a single frequency comb source. This comb-based multi-channel laser cooling could bring significant advances in multi-species atom interferometers for space applications and in the study of multi-species interactions

X-ray Properties of NGC 253's Starburst-Driven Outflow

We analyze image and spectral data from $\approx$365~ks of observations from the {\it Chandra} X-ray Observatory of the nearby, edge-on starburst galaxy NGC~253 to constrain properties of the hot phase of the outflow. We focus our analysis on the $-$1.1 to $+$0.63 kpc region of the outflow and define several regions for spectral extraction where we determine best-fit temperatures and metal abundances. We find that the temperatures and electron densities peak in the central $\sim$250 pc region of the outflow and decrease with distance. These temperature and density profiles are in disagreement with an adiabatic spherically expanding starburst wind model and suggest the presence of additional physics such as mass loading and non-spherical outflow geometry. Our derived temperatures and densities yield few-Myr cooling times in the nuclear region, which may imply that the hot gas can undergo bulk radiative cooling as it escapes along the minor axis. Our metal abundances of O, Ne, Mg, Si, S, and Fe all peak in the central region and decrease with distance along the outflow, with the exception of Ne which maintains a flat distribution. The metal abundances indicate significant dilution outside of the starburst region. We also find estimates on the mass outflow rates which are $2.8\:M_{\odot}/\rm{yr}$ in the northern outflow and $3.2\:M_{\odot}/\rm{yr}$ in the southern outflow. Additionally, we detect emission from charge exchange and find it has a significant contribution ($20-42$\%) to the total broad-band ($0.5-7$~keV) X-ray emission in the central and southern regions of the outflow.Comment: 15 pages, 9 figure

Risk factor control and adherence to treatment in patients with coronary heart disease in the Republic of Srpska, Bosnia and Herzegovina in 2005–2006

Introduction: European treatment guidelines in persons with known coronary heart disease (CHD) focus on adherence to antiplatelet therapy, beta-blockers, ACE/ARBs, and lipid-lowering agents, with goals for blood pressure (BP) of < 140/90 mm Hg and LDL cholesterol of < 3.0 mmol/l. Data on adherence to these measures in Eastern Europe are limited. Material and methods: The Third Republic of Srpska, Bosnia and Herzegovina, Coronary Prevention Study (ROSCOPS III) was conducted in 2005-2006 at 10 primary heath care centres in 601 patients (36% female, mean age 55 years) with CHD including acute myocardial infarction or ischaemia, coronary artery bypass graft, or angioplasty who were examined and interviewed at least 6 months after the event. We examined the proportion of subjects on recommended treatments and at goal for BP, LDL-C, and non-smoking. Results: The proportion of subjects on recommended treatments included 61% for beta-blockers, 79% for ACE/ARBs, 63% for lipid-lowering agents and 74% for antiplatelet therapy. Only 30% of subjects were on all four of these treatments. 59% of subjects had BP at goal of < 140/90 mm Hg and 33% were controlled to < 130/80 mm Hg, 41% for LDL-C, and 88% were non-smokers. Improvements were seen in lipid-lowering and ACE/ARB drug use and non-smoking status from an earlier survey (ROSCOPS II) in 2002-2003. Conclusions: Our data show, despite improvement over recent years, that many persons with CHD in the Republic of Srpska, Bosnia and Herzegovina are neither on recommended treatments nor at target for BP and/or LDL-C. Improved efforts targeted at both physicians and patients to address these issues are needed

On the Nature of the X-ray Emission from the Ultraluminous X-ray Source, M33 X-8: New Constraints from NuSTAR and XMM-Newton

We present nearly simultaneous NuSTAR and XMM-Newton observations of the nearby (832 kpc) ultraluminous X-ray source (ULX) M33 X-8. M33 X-8 has a 0.3-10 keV luminosity of LX ~ 1.4 x 10^39 erg/s, near the boundary of the "ultraluminous" classification, making it an important source for understanding the link between typical Galactic X-ray binaries and ULXs. Past studies have shown that the 0.3-10 keV spectrum of X-8 can be characterized using an advection-dominated accretion disk model. We find that when fitting to our NuSTAR and XMM-Newton observations, an additional high-energy (>10 keV) Comptonization component is required, which allows us to rule out single advection-dominated disk and classical sub-Eddington models. With our new constraints, we analyze XMM-Newton data taken over the last 17 years to show that small (~30%) variations in the 0.3-10 keV flux of M33 X-8 result in spectral changes similar to those observed for other ULXs. The two most likely phenomenological scenarios suggested by the data are degenerate in terms of constraining the nature of the accreting compact object (i.e., black hole versus neutron star). We further present a search for pulsations using our suite of data; however, no clear pulsations are detected. Future observations designed to observe M33 X-8 at different flux levels across the full 0.3-30 keV range would significantly improve our constraints on the nature of this important source.Comment: Accepted for publication in ApJ (15 pages, 4 tables, 6 figures

Astro 2020 Science White Paper: Time Domain Studies of Neutron Star and Black Hole Populations: X-ray Identification of Compact Object Types

What are the most important conditions and processes governing the growth of stellar-origin compact objects? The identification of compact object type as either black hole (BH) or neutron star (NS) is fundamental to understanding their formation and evolution. To date, time-domain determination of compact object type remains a relatively untapped tool. Measurement of orbital periods, pulsations, and bursts will lead to a revolution in the study of the demographics of NS and BH populations, linking source phenomena to accretion and galaxy parameters (e.g., star formation, metallicity). To perform these measurements over sufficient parameter space, a combination of a wide-field (>5000 deg^2) transient X-ray monitor over a dynamic energy range (~1-100 keV) and an X-ray telescope for deep surveys with <5 arcsec PSF half-energy width (HEW) angular resolution are required. Synergy with multiwavelength data for characterizing the underlying stellar population will transform our understanding of the time domain properties of transient sources, helping to explain details of supernova explosions and gravitational wave event rates.Comment: 9 pages, 2 figures. Submitted to the Astro2020 Decadal Surve

Morph-fitting: Fine-tuning word vector spaces with simple language-specific rules

Morphologically rich languages accentuate two properties of distributional vector space models: 1) the difficulty of inducing accurate representations for low-frequency word forms; and 2) insensitivity to distinct lexical relations that have similar distributional signatures. These effects are detrimental for language understanding systems, which may infer that inexpensive is a rephrasing for expensive or may not associate acquire with acquires. In this work, we propose a novel morph-fitting procedure which moves past the use of curated semantic lexicons for improving distributional vector spaces. Instead, our method injects morphological constraints generated using simple language-specific rules, pulling inflectional forms of the same word close together and pushing derivational antonyms far apart. In intrinsic evaluation over four languages, we show that our approach: 1) improves low-frequency word estimates; and 2) boosts the semantic quality of the entire word vector collection. Finally, we show that morph-fitted vectors yield large gains in the downstream task of dialogue state tracking, highlighting the importance of morphology for tackling long-tail phenomena in language understanding tasks

Black Holes and Neutron Stars in Nearby Galaxies: Insights from NuSTAR

Nearby galaxy surveys have long classified X-ray binaries (XRBs) by the mass category of their donor stars (high-mass and low-mass). The NuSTAR observatory, which provides imaging data at E $>10$ keV, has enabled the classification of extragalactic XRBs by their compact object type: neutron star (NS) or black hole (BH). We analyzed NuSTAR/Chandra/XMM-Newton observations from a NuSTAR-selected sample of 12 galaxies within 5 Mpc having stellar masses ($M_{\star}$) $10^{7-11}$ $M_{\odot}$ and star formation rates (SFR) $\approx0.01-15$ $M_{\odot}$ yr$^{-1}$. We detect 128 NuSTAR sources to a sensitivity of $\approx10^{38}$ erg s$^{-1}$. Using NuSTAR color-intensity and color-color diagrams we classify 43 of these sources as candidate NS and 47 as candidate BH. We further subdivide BH by accretion states (soft, intermediate, and hard) and NS by weak (Z/Atoll) and strong (accreting pulsar) magnetic field. Using 8 normal (Milky Way-type) galaxies in the sample, we confirm the relation between SFR and galaxy X-ray point source luminosity in the 4-25 and 12-25 keV energy bands. We also constrain galaxy X-ray point source luminosity using the relation $L_{\rm{X}}=\alpha M_{\star}+\beta\text{SFR}$, finding agreement with previous work. The XLF of all sources in the 4-25 and 12-25 keV energy bands matches with the $\alpha=1.6$ slope for high-mass XRBs. We find that NS XLFs suggest a decline beginning at the Eddington limit for a 1.4 $M_{\odot}$ NS, whereas the BH fraction shows an approximate monotonic increase in the 4-25 and 12-25keV energy bands. We calculate the overall ratio of BH to NS to be $\approx1$ for 4-25 keV and $\approx2$ for 12-25 keV.Comment: 38 pages, 12 figures, 8 tables. ApJ, in pres

Mutations in two global regulators lower individual mortality in Escherichia coli

There has been considerable investigation into the survival of bacterial cells under stress conditions, but little is known about the causes of mortality in the absence of exogenous stress. That there is a basal frequency of cell death in such populations may reflect that it is either impossible to avoid all lethal events, or alternatively, that it is too costly. Here, through a genetic screen in the model organism Escherichia coli, we identify two mutants with lower frequencies of mortality: rssB and fliA. Intriguingly, these two genes both affect the levels of different sigma factors within the cell. The rssB mutant displays enhanced resistance to multiple external stresses, possibly indicating that the cell gains its increased vitality through elevated resistance to spontaneous, endogenous stresses. The loss of fliA does not result in elevated stress resistance; rather, its survival is apparently due to a decreased physical stress linked to the insertion of the flagellum through the membrane and energy saved through the loss of the motor proteins. The identification of these two mutants implies that reducing mortality is not impossible; rather, due to its cost, it is subject to trade-offs with other traits that contribute to the competitive success of the organism