Life cycle assessment of biogas production in small-scale household digesters in Vietnam

Small-scale household digesters have been promoted across Asia as a sustainable way of handling manure. The major advantages are that they produce biogas and reduce odor. However their disadvantages include the low recycling of nutrients, because digestate is dilute and therefore difficult to transport, and the loss of biogas as a result of cracks and the intentional release of excess biogas. In this study, life cycle assessment (LCA) methodology was used to assess the environmental impacts associated with biogas digesters in Vietnam. Handling 1,000 kg of liquid manure and 100 kg of solid manure in a system with a biogas digester reduced the impact potential from 4.4 kg carbon dioxide (CO2) equivalents to 3.2 kg CO2 equivalents compared with traditional manure management. However, this advantage could easily be compromised if digester construction is considered in the LCA or in situations where there is an excess of biogas which is intentionally released. A sensitivity analysis showed that biogas digesters could be a means of reducing global warming if methane emissions can be kept low. In terms of eutrophication, farms with biogas digesters had 3 to 4 times greater impacts. In order to make biogas digesters sustainable, methods for recycling digestates are urgently required

Monolithic Pixel Sensors in Deep-Submicron SOI Technology

Monolithic pixel sensors for charged particle detection and imaging applications have been designed and fabricated using commercially available, deep-submicron Silicon-On-Insulator (SOI) processes, which insulate a thin layer of integrated full CMOS electronics from a high-resistivity substrate by means of a buried oxide. The substrate is contacted from the electronics layer through vias etched in the buried oxide, allowing pixel implanting and reverse biasing. This paper summarizes the performances achieved with a first prototype manufactured in the OKI 0.15 micrometer FD-SOI process, featuring analog and digital pixels on a 10 micrometer pitch. The design and preliminary results on the analog section of a second prototype manufactured in the OKI 0.20 micrometer FD-SOI process are briefly discussed.Comment: Proceedings of the PIXEL 2008 International Workshop, FNAL, Batavia, IL, 23-26 September 2008. Submitted to JINST - Journal of Instrumentatio

Virulence adaptation in a rice leafhopper: Exposure to ineffective genes compromises pyramided resistance

© 2018 The Authors Pyramiding resistance genes is predicted to increase the durability of resistant rice varieties against phloem-feeding herbivores. We examined responses by the green leafhopper, Nephotettix virescens (Hemiptera: Cicadellidae), to near-isogenic rice lines with zero, one and two resistance genes. The recurrent parent (T65) and monogenic lines (GRH2-NIL and GRH4-NIL) with genes for resistance to the green rice leafhopper, Nephotettix cincticeps (Hemiptera: Cicadellidae), were susceptible to the green leafhopper, but the pyramided line (GRH2/GRH4-PYL) was highly resistant to the green leafhopper. We selected green leafhoppers, N. virescens, from five sites in the Philippines for over 20 generations on each of the four lines. Populations selected on GRH2/GRH4-PYL gained partial virulence (feeding and development equal to that on T65) to the pyramided line within 10 generations and complete virulence (egg-laying equal to that on T65) within 20 generations. After 20 generations of rearing on the susceptible monogenic lines, green leafhoppers were also capable of developing and laying eggs on GRH2/GRH4-PYL. Furthermore, green leafhoppers reared on the susceptible GRH4-NIL for 20 generations showed equal preferences for T65 and GRH2/GRH4-PYL in choice bioassays. Our results indicate that previous long-term exposure to ineffective genes (including unperceived resistance genes) could dramatically reduce the durability of pyramided resistance. We suggest that informed crop management and deployment strategies should be developed to accompany rice lines with pyramided resistance and avoid the build-up of virulent herbivore populations

Methane emission factors from vietnamese rice production: Pooling data of 36 field sites for meta-analysis

Rice production is a significant source of greenhouse gas (GHG) emissions in the national budget of many Asian countries, but the extent of emissions varies strongly across agro-environmental zones. It is important to understand these differences in order to improve the national GHG inventory and effectively target mitigation options. This study presents a meta-analysis of CH4 database emission factors (EFs) from 36 field sites across the rice growing areas of Vietnam and covering 73 cropping seasons. The EFs were developed from field measurements using the closed chamber technique. The analysis for calculating baseline EFs in North, Central and South Vietnam in line with the Intergovernmental Panel on Climate Change (IPCC) Tier 2 methodology was specified for the three cropping seasons being early-(E), mid-(M) and late-year (L) seasons. Calculated average CH$_{4}$ EFs are given in kg ha$^{-1}$ d$^{-1}$ and reflect the distinct seasons in North (E: 2.21; L: 3.89), Central (E: 2.84; M+L: 3.13) and South Vietnam (E: 1.72; M: 2.80; L: 3.58). Derived from the available data of the edapho-hydrological zones of the Mekong River Delta, season-based EFs are more useful than zone-based EFs. In totality, these average EFs indicate an enormous variability of GHG emissions in Vietnamese rice production and represent much higher values than the IPCC default. Seasonal EFs from Vietnam exceeded IPCC defaults given for Southeast Asia corresponding to 160% (E), 240% (M) and 290% (L) of the medium value, respectively

Evaluating the Ability of Swell Prediction Models to Predict the Swell Behavior of Excessively High Plastic Soils

Lightly loaded structures underneath expansive soils encounter severe damage due to the swell/shrink nature of expansive soils resulting from moisture variations. Billions of dollars are spent every year to repair the damages caused by these soils in the U.S. and worldwide. Designing structures to accommodate the swelling strains is a major challenge as predicting the swelling potential of these soils accurately is not easy. A wide variety of swell prediction models have been introduced by various researchers to predict the behavior of these often-problematic expansive soils. These models include various properties of soils such as, plasticity characteristics, compaction conditions, consolidation characteristics, moisture content variations, matric suction, and clay mineralogical characteristics. However, these models are generally developed with typical moderate to high plastic soils in mind whose plasticity indices range from 25 to 45. Their applicability to soils that have liquid limits in the order of 200% is not well understood. In this paper, the ability of these models to predict the behavior of excessively high plastic soils with plasticity indices ranging from 45 to 85 were evaluated. For this purpose, four existing analytical prediction models that use combinations of above-mentioned properties were selected and used to predict the one-dimensional and three-dimensional swelling strains on three high swelling soils. These predictions were verified by conducting one-dimensional and three-dimensional swell tests on the three soil types. The swell tests were conducted at three different initial moisture contents to observe how well the models could predict different levels of moisture absorption. The ability of each of the four selected methods in predicting both 1D and 3D swell strains was discussed and their relative merits and demerits are highlighted. In addition, finite element modeling was performed to simulate one-dimensional and three-dimensional swell tests by using material models that use volumetric and suction changes with moisture contents to simulate expansive soil behavior within the finite element model. The results indicated that while the analytical prediction models gave reasonable results the finite element analysis predicted results were closest to the laboratory measure soils in case both 1D and 3D analyses. Among other analytical models the ones that incorporated mineralogical and suction data exhibited better results

Flexural-strengthening efficiency of cfrp sheets for unbonded post-tensioned concrete T-beams

There has been a limited number of studies about the flexural behavior of unbonded post-tensioned concrete (UPC) beams strengthened with carbon fibre reinforced polymer (CFRP) and these studies have not systematically examined the effect of CFRP sheets on the tendon strain as well as the strengthening efficiency. Moreover, current design guides for the FRP strengthening techniques have not provided any design procedure for UPC structures. This study, thus, investigates the influence of CFRP sheet ratio on the flexural behavior of CFRP-strengthened UPC T-beams and quantifies its effect upon tendon behavior in this kind of UPC beams. The testing program consisted of nine large-scale UPC T-beams strengthened by different layers of CFRP sheets with or without CFRP U-wrapped anchors. The experimental results have shown that the use of CFRP sheets and CFRP U-wrapped anchors significantly affected the tendon strain. The FRP reinforcement ratio governed the flexural capacity, the crack width, the mid-span displacement, and the ductility of the beams in which the strengthening efficiency reduces with the increased number of CFRP layers. The configuration of the CFRP U-wrapped anchors affected the strain of the CFRP sheets, the failure mode and thus the beam behavior. In addition, semi-empirical equations were proposed to estimate the actual strain of unbonded tendons in which the effect of the CFRP sheets and CFRP U-wrapped anchors have been taken into consideration. The proposed equations, which are simple to use, yield reliable predictions with a small variation

Simple clinical and laboratory predictors to improve empirical treatment strategies in areas of high scrub typhus and dengue endemicity, central Vietnam

BACKGROUND: Dengue fever is highly endemic in Vietnam, but scrub typhus-although recognized as an endemic disease-remains underappreciated. These diseases together are likely to account for more than half of the acute undifferentiated fever burden in Vietnam. Scrub typhus (ST) is a bacterial disease requiring antimicrobial treatment, while dengue fever (DF) is of viral etiology and does not. The access to adequate diagnostics and the current understanding of empirical treatment strategies for both illnesses remain limited. In this study we aimed to contribute to the clinical decision process in the management of these two important etiologies of febrile illness in Vietnam. METHODS: Using retrospective data from 221 PCR-confirmed scrub typhus cases and 387 NS1 protein positive dengue fever patients admitted to five hospitals in Khanh Hoa province (central Vietnam), we defined predictive characteristics for both diseases that support simple clinical decision making with potential to inform decision algorithms in future. We developed models to discriminate scrub typhus from dengue fever using multivariable logistic regression (M-LR) and classification and regression trees (CART). Regression trees were developed for the entire data set initially and pruned, based on cross-validation. Regression models were developed in a training data set involving 60% of the total sample and validated in the complementary subsample. Probability cut points for the distinction between scrub typhus and dengue fever were chosen to maximise the sum of sensitivity and specificity. RESULTS: Using M-LR, following seven predictors were identified, that reliably differentiate ST from DF; eschar, regional lymphadenopathy, an occupation in nature, increased days of fever on admission, increased neutrophil count, decreased ratio of neutrophils/lymphocytes, and age over 40. Sensitivity and specificity of predictions based on these seven factors reached 93.7% and 99.5%, respectively. When excluding the "eschar" variable, the values dropped to 76.3% and 92.3%, respectively. The CART model generated one further variable; increased days of fever on admission, when eschar was included, the sensitivity and specificity was 95% and 96.9%, respectively. The model without eschar involved the following six variables; regional lymphadenopathy, increased days of fever on admission, increased neutrophil count, increased lymphocyte count, platelet count >/= 47 G/L and age over 28 years as predictors of ST and provided a sensitivity of 77.4% and a specificity of 90.7%. CONCLUSIONS: The generated algorithms contribute to differentiating scrub typhus from dengue fever using basic clinical and laboratory parameters, supporting clinical decision making in areas where dengue and scrub typhus are co-endemic in Vietnam

Role of Esrrg in the Fibrate-Mediated Regulation of Lipid Metabolism Genes in Human ApoA-I Transgenic Mice

We have used a new ApoA-I transgenic mouse model to identify by global gene expression profiling, candidate genes that affect lipid and lipoprotein metabolism in response to fenofibrate treatment. Multilevel bioinformatical analysis and stringent selection criteria (2-fold change, 0% false discovery rate) identified 267 significantly changed genes involved in several molecular pathways. The fenofibrate-treated group did not have significantly altered levels of hepatic human APOA-I mRNA and plasma ApoA-I compared with the control group. However, the treatment increased cholesterol levels to 1.95-fold mainly due to the increase in high-density lipoprotein (HDL) cholesterol. The observed changes in HDL are associated with the upregulation of genes involved in phospholipid biosynthesis and lipid hydrolysis, as well as phospholipid transfer protein. Significant upregulation was observed in genes involved in fatty acid transport and β-oxidation, but not in those of fatty acid and cholesterol biosynthesis, Krebs cycle and gluconeogenesis. Fenofibrate changed significantly the expression of seven transcription factors. The estrogen receptor-related gamma gene was upregulated 2.36-fold and had a significant positive correlation with genes of lipid and lipoprotein metabolism and mitochondrial functions, indicating an important role of this orphan receptor in mediating the fenofibrate-induced activation of a specific subset of its target genes.National Institutes of Health (HL48739 and HL68216); European Union (LSHM-CT-2006-0376331, LSHG-CT-2006-037277); the Biomedical Research Foundation of the Academy of Athens; the Hellenic Cardiological Society; the John F Kostopoulos Foundatio