175 research outputs found
Development of an integrated cognitive behavioral therapy for anxiety and opioid use disorder: Study protocol and methods
Opioid use disorder is a highly disabling psychiatric disorder, and is associated with both significant functional disruption and risk for negative health outcomes such as infectious disease and fatal overdose. Even among those who receive evidence-based pharmacotherapy for opioid use disorder, many drop out of treatment or relapse, highlighting the importance of novel treatment strategies for this population. Over 60% of those with opioid use disorder also meet diagnostic criteria for an anxiety disorder; however, efficacious treatments for this common co-occurrence have not be established. This manuscript describes the rationale and methods for a behavioral treatment development study designed to develop and test an integrated cognitive-behavioral therapy for those with co-occurring opioid use disorder and anxiety disorders. The aims of the study are (1) to develop and pilot test a new manualized cognitive behavioral therapy for co-occurring opioid use disorder and anxiety disorders, (2) to test the efficacy of this treatment relative to an active comparison treatment that targets opioid use disorder alone, and (3) to investigate the role of stress reactivity in both prognosis and recovery from opioid use disorder and anxiety disorders. Our overarching aim is to investigate whether this new treatment improves both anxiety and opioid use disorder outcomes relative to standard treatment. Identifying optimal treatment strategies for this population are needed to improve outcomes among those with this highly disabling and life-threatening disorder.This study was funded by NIDA grant DA035297. The funding source had no involvement in the study design, analysis and interpretation of data, writing of the report, or the decision to submit the article for publication. (DA035297 - NIDA)Accepted manuscrip
The detailed method of optimal regions
The detailed method of optimal regions is an extended form of the method of optimal regions which has been found effective in solving the personnel classification problem when the number of job categories is small. The automatic determination of the successive values of the v i , made possible by the more exact techniques of the detailed method, provide easier solutions for the more complex problems and provide solutions, which, for the most part, can be mechanized. In a sense the detailed method of optimal regions is more than a detailed form of the method of optimal regions. It is essentially a method of transformations by which the original matrix is reduced to a matrix from which the solution is easily obtained.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/45700/1/11336_2005_Article_BF02289208.pd
The mean and standard deviation of the distribution of group assembly sums
An interesting problem in linear programming is the group assembly problem which is mathematically equivalent to the general transportation problem of economics. Computer programs designed for the determination of exact and approximate optimal group assemblies have been available for some time. This paper presents formulas for the mean and squared standard deviation of the distribution of all possible group assembly sums. Computational techniques are presented and the results are related to those of the analysis of variance of a k -factor problem with n levels of each factor.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/45717/1/11336_2005_Article_BF02289606.pd
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Overview of charged-particle beam diagnostics for the Advanced Photon Source (APS)
Plans, prototypes, and initial test results for the charged-particle beam (e[sup [minus]],e[sup +]) diagnostic systems on the injector rings, their transport lines, and the storage ring for the Advanced Photon Source (APS) are presented. The APS will be a synchrotron radiation user facility with one of the world's brightest x-ray sources in the 10-keV to 100-keV regime. Its 200-MeV electron linac, 450-MeV positron linac, positron accumulator ring, 7-GeV booster synchrotron, 7-GeV storage ring, and undulator test lines will also demand the development and demonstration of key particle-beam characterization techniques over a wide range of parameter space. Some of these parameter values overlap or approach those projected for fourth generation light sources (linac-driven FELs and high brightness storage rings) as described at a recent workshop. Initial results from the diagnostics prototypes on the linac test stand operating at 45-MeV include current monitor data, beam loss monitor data, and video digitization using VME architecture
Cross-Section Measurement of Virtual Photoproduction of Iso-Triplet Three-Body Hypernucleus, ⋀nn
Missing-mass spectroscopy with the 3H(e, e′K+) reaction was carried out at Jefferson Lab’s (JLab) Hall A in Oct–Nov, 2018. The differential cross section for the 3H(γ∗, K+)Λnn was deduced at ω = Ee − Ee′ = 2.102 GeV and at the forward K+-scattering angle (0° ≤ θγ∗K ≤ 5°) in the laboratory frame. Given typical predicted energies and decay widths, which are (BΛ, Γ) = (−0.25, 0.8) and (−0.55, 4.7) MeV, the cross sections were found to be 11.2 ± 4.8(stat.)+4.1−2.1(sys.) and 18.1 ± 6.8(stat.)+4.2−2.9(sys.) nb/sr, respectively. The obtained result would impose a constraint for interaction models particularly between Λ and neutron by comparing to theoretical calculations
Revealing the short-range structure of the "mirror nuclei" H and He
When protons and neutrons (nucleons) are bound into atomic nuclei, they are
close enough together to feel significant attraction, or repulsion, from the
strong, short-distance part of the nucleon-nucleon interaction. These strong
interactions lead to hard collisions between nucleons, generating pairs of
highly-energetic nucleons referred to as short-range correlations (SRCs). SRCs
are an important but relatively poorly understood part of nuclear structure and
mapping out the strength and isospin structure (neutron-proton vs proton-proton
pairs) of these virtual excitations is thus critical input for modeling a range
of nuclear, particle, and astrophysics measurements. Hitherto measurements used
two-nucleon knockout or ``triple-coincidence'' reactions to measure the
relative contribution of np- and pp-SRCs by knocking out a proton from the SRC
and detecting its partner nucleon (proton or neutron). These measurementsshow
that SRCs are almost exclusively np pairs, but had limited statistics and
required large model-dependent final-state interaction (FSI) corrections. We
report on the first measurement using inclusive scattering from the mirror
nuclei H and He to extract the np/pp ratio of SRCs in the A=3 system.
We obtain a measure of the np/pp SRC ratio that is an order of magnitude more
precise than previous experiments, and find a dramatic deviation from the
near-total np dominance observed in heavy nuclei. This result implies an
unexpected structure in the high-momentum wavefunction for He and H.
Understanding these results will improve our understanding of the short-range
part of the N-N interaction
Towards the Development of an Empirical Model for Islamic Corporate Social Responsibility: Evidence from the Middle East
Academic research suggests that variances in contextual dynamics, and more specifically religion, may lead to disparate perceptions and practices of corporate social responsibility (CSR). Driven by the increased geopolitical and economic importance of the Middle East and identified gaps in knowledge, the study aims to examine if indeed there is a divergent form of CSR exercised in the region. The study identifies unique CSR dimensions and constructs presented through an empirical framework in order to outline the practice and perception of CSR in a context with strong Islamic beliefs. The framework goes beyond the platform of mere Islamic philanthropy and is based on CSR-stakeholder management practices. Following an exploratory research design and collecting interview data from representatives of 63 organisations from Saudi Arabia, the United Arab Emirates and Oman, the study offers a snapshot of the CSR reality from the perspective of those living the phenomenon. The results suggest that the practice and perception of CSR in the examined context are largely grounded in the areas of social and altruistic actions but they cannot be examined in isolation from the religious context of CSR operation. This focus is mainly attributed to the dominant role of Islam in the examined sample, which leads to forms of non-structured or semi-structured approaches to CSR. Apart from the theoretical advancements offered to the CSR literature, the study also provides contributions for practitioners and policy makers.</p
Novel measurement of the neutron magnetic form factor from A=3 mirror nuclei
The electromagnetic form factors of the proton and neutron encode information on the spatial structure of their charge and magnetization distributions. While measurements of the proton are relatively straightforward, the lack of a free neutron target makes measurements of the neutron's electromagnetic structure more challenging and more sensitive to experimental or model-dependent uncertainties. Various experiments have attempted to extract the neutron form factors from scattering from the neutron in deuterium, with different techniques providing different, and sometimes large, systematic uncertainties. We present results from a novel measurement of the neutron magnetic form factor using quasielastic scattering from the mirror nuclei ^{3}H and ^{3}He, where the nuclear effects are larger than for deuterium but expected to largely cancel in the cross-section ratios. We extracted values of the neutron magnetic form factor for low-to-modest momentum transfer, 0.6<Q^{2}<2.9 GeV^{2}, where existing measurements give inconsistent results. The precision and Q^{2} range of these data allow for a better understanding of the current world's data and suggest a path toward further improvement of our overall understanding of the neutron's magnetic form factor
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