34 research outputs found
Alumnae Association Bulletin of the School of Nursing, 1972
Alumnae Calendar
The President\u27s Message
Officers and Chairmen of Committees
Financial Report
Address by President Herbut
School of Nursing Report
School of Practical Nursing Report
Report by Dr. Mary Louise Soentgen, M.D., F.A.A.P.
Report of Patient Services Department
Report of Staff Nurses\u27 Association
Progress Report of Hospital Activities
Scholarship Committee
Report - Clerk-Typist
Annual Luncheon - Head Table
Social Events for 1971-1972
Missing Alumnae Members
Jefferson Today
Ways and Means Committee Report
Constitution and By-Laws Report
Sick and Welfare Committee
Women\u27s Board Report
Baccalaureate Degree Program
Luncheon Pictures
Resume of Minutes of Alumnae Association Meeting
Class News
Poem by Rosa Diseroad - 1923
Marriages
Births - Hello World
In Memoriam
Notice
Alumnae Association Bulletin of the School of Nursing, 1973
Alumnae Calendar
The President\u27s Message
Officers and Chairmen of Committees
Financial Report
Annual Reports
Named to Academy of Nursing
Alumnae Association Relief Fund Benefits
Sesquicentennial - A Celebration and a Challenge
Progress of the Thomas Jefferson University Hospital 1972-1973
Report of the Patient Services Department
Changes in the Department of Radiation Therapy
Annual Luncheon
Committee Reports
Administration
Missing Alumnae Members
Salute to Life Members
The Class of 1973
Ways and Means Committee Report
Resume of Minutes of Alumnae Association Meetings
Class Notes
Marriages
Births
In Memoriam
Notice
The Bulletin, School of Nursing Alumni Association, 1978
Alumni Calendar
Recognition Plaque
A Letter from the President
Officers and Chairpersons
Jefferson - Past, Present and Future
Annual Reports
School of Practical Nursing
Sesqui Pledge Completed
Alumnae Data 1891-1978
Committee Reports
A.N.A. Convention Report
The Liberation of a POW
Resume of Alumni Meetings
Cocktails and Conversation
Class News
Luncheon Gusts - Class of 1978
Marriages
Births
In Memoriam
Alumni Notices
School of Nursing Notice
The Bulletin, School of Nursing Diploma Program Alumni Association, 1979
Alumni Calendar
Recognition Plaque
A Letter from the President
Officers and Chairpersons
The Future of Nursing Education at Jefferson
Annual Reports
Alumni Benefits
Memo from Your President
Resume of Alumni Association Meetings
Committee Reports
The Nursing Alumni Office Serves You
Profiles in Courage
Special Reports
Ways and Means Committee Report
38th General Hospital Reunion
College of Allied Health Sciences Achievement Award
Class News
Marriages
Births
In Memoriam
Alumni Notices
School of Nursing Notice
Alumni Association Bulletin of the School of Nursing, 1976
Alumni Calendar
The President\u27s Message
Officers and Chairpersons of Committees
Financial Report
Annual Reports
New Surgical Concept for Laryngeal Cancer
Computerized Transaxial X-ray Scanner
Dental Health Center
The Winged Ox of St. Luke
Pictures - New Building
Committee Reports
Resume of Alumni Minutes
Ways and Means Report
Alumni News
Class News
Names and Addresses of 1976 Graduates
School of Nursing 1976 Awards
Marriages
Births
In Memoriam - List of Alumni
In Memoriam - Dr. Peter A. Herbut
In Memoriam - Miss Katherine Childs
Change of Address Notice
Notice
The Bulletin, School of Nursing Alumnae Association, 1977
A Letter from the President
Progress - The New Jefferson Hospital/Clinical Teaching Facility 1977
School of Nursing
A Comprehensive Approach to Hand Rehabilitation
Parking Garage
Your Sesquicentennial Campaign
Social Report
Scholarship Report
Sick and Welfare Committee
Program Committee
Resource Committee of the Board of Trustees
Bulletin
Administration
Ways and Means Committee Report
Resume of Minutes of Alumnae Association Meetings
Duke University Distinguished Alumna Award to Col. Catherine T. Betz (Ret.)
Patient Representatives
The Joys and Sorrows of a Director of Geriatric Nursing
Highlights 1976 P.N.A Convention
Class News
Marriages
Births
In Memoriam
A Letter from the Former President
Help Us - Help Yo
Clustering patients on the basis of their individual course of low back pain over a six month period
<p>Abstract</p> <p>Background</p> <p>Several researchers have searched for subgroups in the heterogeneous population of patients with non-specific low back pain (LBP). To date, subgroups have been identified based on psychological profiles and the variation of pain.</p> <p>Methods</p> <p>This multicentre prospective observational study explored the 6- month clinical course with measurements of bothersomeness that were collected from weekly text messages that were sent by 176 patients with LBP. A hierarchical cluster analysis, Ward's method, was used to cluster patients according to the development of their pain.</p> <p>Results</p> <p>Four clusters with distinctly different clinical courses were described and further validated against clinical baseline variables and outcomes. Cluster 1, a "stable" cluster, where the course was relatively unchanged over time, contained young patients with good self- rated health. Cluster 2, a group of "fast improvers" who were very bothered initially but rapidly improved, consisted of patients who rated their health as relatively poor but experienced the fewest number of days with bothersome pain of all the clusters. Cluster 3 was the "typical patient" group, with medium bothersomeness at baseline and an average improvement over the first 4-5 weeks. Finally, cluster 4 contained the "slow improvers", a group of patients who improved over 12 weeks. This group contained older individuals who had more LBP the previous year and who also experienced most days with bothersome pain of all the clusters.</p> <p>Conclusions</p> <p>It is possible to define clinically meaningful clusters of patients based on their individual course of LBP over time. Future research should aim to reproduce these clusters in different populations, add further clinical variables to distinguish the clusters and test different treatment strategies for them.</p
Transcriptional diversity during lineage commitment of human blood progenitors.
Blood cells derive from hematopoietic stem cells through stepwise fating events. To characterize gene expression programs driving lineage choice, we sequenced RNA from eight primary human hematopoietic progenitor populations representing the major myeloid commitment stages and the main lymphoid stage. We identified extensive cell type-specific expression changes: 6711 genes and 10,724 transcripts, enriched in non-protein-coding elements at early stages of differentiation. In addition, we found 7881 novel splice junctions and 2301 differentially used alternative splicing events, enriched in genes involved in regulatory processes. We demonstrated experimentally cell-specific isoform usage, identifying nuclear factor I/B (NFIB) as a regulator of megakaryocyte maturation-the platelet precursor. Our data highlight the complexity of fating events in closely related progenitor populations, the understanding of which is essential for the advancement of transplantation and regenerative medicine.The work described in this article was primarily supported by the European Commission Seventh Framework Program through the BLUEPRINT grant with code HEALTH-F5-2011-282510 (D.H., F.B., G.C., J.H.A.M., K.D., L.C., M.F., S.C., S.F., and S.P.G.). Research in the Ouwehand laboratory is further supported by program grants from the National Institute for Health Research (NIHR, www.nihr.ac.uk; to A.A., M.K., P.P., S.B.G.J., S.N., and W.H.O.) and the British Heart Foundation under nos. RP-PG-0310-1002 and RG/09/12/28096 (www.bhf.org.uk; to A.R. and W.J.A.). K.F. and M.K. were supported by Marie Curie funding from the NETSIM FP7 program funded by the European Commission. The laboratory receives funding from the NHS Blood and Transplant for facilities. The Cambridge BioResource (www.cambridgebioresource.org.uk), the Cell Phenotyping Hub, and the Cambridge Translational GenOmics laboratory (www.catgo.org.uk) are supported by an NIHR grant to the Cambridge NIHR Biomedical Research Centre (BRC). The BRIDGE-Bleeding and Platelet Disorders Consortium is supported by the NIHR BioResource—Rare Diseases (http://bioresource.nihr.ac.uk/; to E.T., N.F., and Whole Exome Sequencing effort). Research in the Soranzo laboratory (L.V., N.S., and S. Watt) is further supported by the Wellcome Trust (Grant Codes WT098051 and WT091310) and the EU FP7 EPIGENESYS initiative (Grant Code 257082). Research in the Cvejic laboratory (A. Cvejic and C.L.) is funded by the Cancer Research UK under grant no. C45041/A14953. S.J.S. is funded by NIHR. M.E.F. is supported by a British Heart Foundation Clinical Research Training Fellowship, no. FS/12/27/29405. E.B.-M. is supported by a Wellcome Trust grant, no. 084183/Z/07/Z. Research in the Laffan laboratory is supported by Imperial College BRC. F.A.C., C.L., and S. Westbury are supported by Medical Research Council Clinical Training Fellowships, and T.B. by a British Society of Haematology/NHS Blood and Transplant grant. R.J.R. is a Principal Research Fellow of the Wellcome Trust, grant no. 082961/Z/07/Z. Research in the Flicek laboratory is also supported by the Wellcome Trust (grant no. 095908) and EMBL. Research in the Bertone laboratory is supported by EMBL. K.F. and C.v.G. are supported by FWO-Vlaanderen through grant G.0B17.13N. P.F. is a compensated member of the Omicia Inc. Scientific Advisory Board. This study made use of data generated by the UK10K Consortium, derived from samples from the Cohorts arm of the project.This is the author’s version of the work. It is posted here by permission of the AAAS for personal use, not for redistribution. The definitive version was published in Science on 26/9/14 in volume 345, number 6204, DOI: 10.1126/science.1251033. This version will be under embargo until the 26th of March 2015