162 research outputs found
Passive sampling of polychlorinated biphenyls (PCB) in indoor air:towards a cost-effective screening tool
A review of the occurrence of metals and xenobiotics in European hedgehogs (Erinaceus europaeus)
The European hedgehog (Erinaceus europaeus) is a popular visitor in gardens and recreational areas all over Europe, but hedgehog populations are declining. Research exploring the causes of the decline, including exposure to potentially harmful pollutants and metals, may provide relevant information to improve conservation initiatives to protect this species in the wild. Hedgehogs are ground-dwelling mammals, feeding on a range of different food items such as insects, slugs, snails, and earthworms but also eggs, live vertebrates, and carrion, and therefore come into close contact with pollutants present in their habitats and in their prey. This review investigated published research on the occurrence of metals and pollutants in hedgehogs and found that a vast range of different pesticides; rodenticides; persistent organic pollutants (POPs), including organochlorine compounds and brominated flame retardants (BFRs); as well as toxic heavy metals could be detected in samples from hedgehogs representing different European countries. Due to their ecology, combined with the opportunity to apply non-invasive sampling techniques through the collection of spines as sampling material, we suggest that the European hedgehog is a relevant bioindicator species for monitoring the exposure of omnivorous terrestrial wildlife to potential toxicants in urban and rural environments
Raptors are still affected by environmental pollutants:Greenlandic Peregrines will not have normal eggshell thickness until 2034
The DDT-induced effects, eggshell thinning and breeding failure in Peregrine Falcon (Falco peregrinus) populations were reverted with restrictions on the use of the compound from the 1970s, and in most studied populations, the eggshell thickness is back to normal. In Greenland, a previous study of eggshell thinning in Peregrines found that shells had not yet reached pre-DDT levels. In this study, we extend the time series and reinterpret shell thinning data for 196 clutches covering a 45-year time span (1972–2017). There was a significant (P<0.001) increase in the eggshell thickness of 0.23% per year. This corresponds to a change in eggshell thinning from 14.5% to 5.4% in 2017 compared to the pre-DDT mean. With the current rate of change, pre-DDT shell thickness is predicted to be reached around the year 2034. However, a few clutches are still below the critical limit. The relatively slower recovery of the shell thickness in the Greenland population is likely indicative of the slower phasing out of DDT in the Greenlandic Peregrines’ wintering grounds in Latin America. The shell thinning in the Greenlandic population probably never crossed the 17% threshold associated with population declines, contrary to the populations in many other parts of the world
New and updated time trends of persistent organic pollutants and their effects on eggs of peregrine falcons (Falco peregrinus) from South Greenland
Polybrominated diphenyl ethers and novel flame retardants:associations between dust and human milk
Silicone wristbands as personal passive samplers of exposure to polychlorinated biphenyls in contaminated buildings
Effects of the Commercial Flame Retardant Mixture DE-71 on Cytokine Production by Human Immune Cells
INTRODUCTION:Although production of polybrominated diphenyl ethers (PBDEs) is now banned, release from existing products will continue for many years. The PBDEs are assumed to be neurotoxic and toxic to endocrine organs at low concentrations. Their effect on the immune system has not been investigated thoroughly. We aimed to investigate the influence of DE-71 on cytokine production by peripheral blood mononuclear cells (PBMCs) stimulated with Escherichia Coli lipopolysaccharide (LPS) or phytohaemagglutinin-L (PHA-L). MATERIAL AND METHODS:PBMCs isolated from healthy donors were pre-incubated with DE-71 at various concentrations and subsequently incubated with the monocyte stimulator LPS, or the T-cell activator PHA-L. Interferon (IFN)-γ, interleukin (IL)-1β, IL-2, IL-4, IL-6, IL-8, IL-10, tumor necrosis factor (TNF)-α, IL-17A, and IL-17F were quantified in the supernatants by Luminex kits. RESULTS:At non-cytotoxic concentrations (0.01-10 μg/mL), DE-71 significantly enhanced secretion of IL-1β, IL-6, CXCL8, IL-10, and TNF-α (p<0.001-0.019; n = 6) from LPS-stimulated PBMCs. IFN-γ, TNF-α, IL-17A, and IL-17F (p = <0.001-0.043; n = 6) secretion were enhanced from PHA-L-stimulated PBMCs as well. Secretion of IL-1β, IL-2, IL-10, IL-8 and IL-6 was not significantly affected by DE-71. CONCLUSIONS:We demonstrate an enhancing effect of DE-71 on cytokine production by normal human PBMCs stimulated with LPS or PHA-L ex vivo
Multiple coating thicknesses for sampling of organic pollutants – linear regressions confirm equilibrium even in challenging environmental media
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