445 research outputs found
The GREGOR Fabry-P\'erot Interferometer
The GREGOR Fabry-P\'erot Interferometer (GFPI) is one of three first-light
instruments of the German 1.5-meter GREGOR solar telescope at the Observatorio
del Teide, Tenerife, Spain. The GFPI uses two tunable etalons in collimated
mounting. Thanks to its large-format, high-cadence CCD detectors with
sophisticated computer hard- and software it is capable of scanning spectral
lines with a cadence that is sufficient to capture the dynamic evolution of the
solar atmosphere. The field-of-view (FOV) of 50" x 38" is well suited for quiet
Sun and sunspot observations. However, in the vector spectropolarimetric mode
the FOV reduces to 25" x 38". The spectral coverage in the spectroscopic mode
extends from 530-860 nm with a theoretical spectral resolution R of about
250,000, whereas in the vector spectropolarimetric mode the wavelength range is
at present limited to 580-660 nm. The combination of fast narrow-band imaging
and post-factum image restoration has the potential for discovery science
concerning the dynamic Sun and its magnetic field at spatial scales down to
about 50 km on the solar surface.Comment: 14 pages, 17 figures, 4 tables; pre-print of AN 333, p.880-893, 2012
(AN special issue to GREGOR
High-level feature detection from video in TRECVid: a 5-year retrospective of achievements
Successful and effective content-based access to digital
video requires fast, accurate and scalable methods to determine the video content automatically. A variety of contemporary approaches to this rely on text taken from speech within the video, or on matching one video frame against others using low-level characteristics like
colour, texture, or shapes, or on determining and matching objects appearing within the video. Possibly the most important technique, however, is one which determines the presence or absence of a high-level or semantic feature, within a video clip or shot. By utilizing dozens, hundreds or even thousands of such semantic features we can support many kinds of content-based video navigation. Critically however, this depends on being able to determine whether each feature is or is not present in a video clip.
The last 5 years have seen much progress in the development of techniques to determine the presence of semantic features within video. This progress can be tracked in the annual TRECVid benchmarking activity where dozens of research groups measure the effectiveness of their techniques on common data and using an open, metrics-based approach. In this chapter we summarise the work
done on the TRECVid high-level feature task, showing the
progress made year-on-year. This provides a fairly comprehensive statement on where the state-of-the-art is regarding this important task, not just for one research group or for one approach, but across the spectrum. We then use this past and on-going work as a basis for highlighting the trends that are emerging in this area, and the questions which remain to be addressed before we can
achieve large-scale, fast and reliable high-level feature detection on video
Photospheric Magnetic Fields of the Trailing Sunspots in Active Region NOAA 12396
The solar magnetic field is responsible for all aspects of solar activity.
Sunspots are the main manifestation of the ensuing solar activity. Combining
high-resolution and synoptic observations has the ambition to provide a
comprehensive description of the sunspot growth and decay processes. Active
region NOAA 12396 emerged on 2015 August 3 and was observed three days later
with the 1.5-meter GREGOR solar telescope on 2015 August 6. High-resolution
spectropolarimetric data from the GREGOR Infrared Spectrograph (GRIS) are
obtained in the photospheric Si I 1082.7 nm and Ca I 1083.9
nm lines, together with the chromospheric He I 1083.0 nm triplet.
These near-infrared spectropolarimetric observations were complemented by
synoptic line-of-sight magnetograms and continuum images of the Helioseismic
and Magnetic Imager (HMI) and EUV images of the Atmospheric Imaging Assembly
(AIA) on board the Solar Dynamics Observatory (SDO).Comment: 4 pages, 2 figures, to be published in "Solar Polarization Workshop
8", ASP Proceedings, Luca Belluzzi (eds.
Principles and philosophies for speech and language therapists working with people with primary progressive aphasia: An international expert consensus
Purpose: Primary progressive aphasia (PPA) is a language-led dementia associated with Alzheimerâs pathology and fronto-temporal lobar degeneration. Multiple tailored speech and language interventions have been developed for people with PPA. Speech and language therapists/speech-language pathologists (SLT/Ps) report lacking confidence in identifying the most pertinent interventions options relevant to their clients living with PPA during their illness trajectory. Materials and methods: The aim of this study was to establish a consensus amongst 15 clinical-academic SLT/Ps on best practice in selection and delivery of speech and language therapy interventions for people with PPA. An online nominal group technique (NGT) and consequent focus group session were held. NGT rankings were aggregated and focus groups video recorded, transcribed, and reflexive thematic analysis undertaken. Results: The results of the NGT identified 17 items. Two main themes and seven further subthemes were identified in the focus groups. The main themes comprised (1) philosophy of person-centredness and (2) complexity. The seven subthemes were knowing people deeply, preventing disasters, practical issues, professional development, connectedness, barriers and limitations, and peer support and mentoring towards a shared understanding. Conclusions: This study describes the philosophy of expert practice and outlines a set of best practice principles when working with people with PPA.Implications for rehabilitation Primary progressive aphasia (PPA) describes a group of language led dementias which deteriorate inexorably over time. Providing speech and language therapy for people with PPA is complex and must be person centred and bespoke. This study describes the philosophy of expert practice and outlines a set of best practice principles for speech and language therapists/pathologists working with people with people with PPA
A retrospective of the GREGOR solar telescope in scientific literature
In this review, we look back upon the literature, which had the GREGOR solar
telescope project as its subject including science cases, telescope subsystems,
and post-focus instruments. The articles date back to the year 2000, when the
initial concepts for a new solar telescope on Tenerife were first presented at
scientific meetings. This comprehensive bibliography contains literature until
the year 2012, i.e., the final stages of commissioning and science
verification. Taking stock of the various publications in peer-reviewed
journals and conference proceedings also provides the "historical" context for
the reference articles in this special issue of Astronomische
Nachrichten/Astronomical Notes.Comment: 6 pages, 2 color figures, this is the pre-peer reviewed version of
Denker et al. 2012, Astron. Nachr. 333, 81
Development of a Multiphoton Fluorescence Lifetime Imaging Microscopy (FLIM) system using a Streak Camera
We report the development and detailed calibration of a multiphoton
fluorescence lifetime imaging system (FLIM) using a streak camera. The present
system is versatile with high spatial (0.2 micron) and temporal (50 psec)
resolution and allows rapid data acquisition and reliable and reproducible
lifetime determinations. The system was calibrated with standard fluorescent
dyes and the lifetime values obtained were in very good agreement with values
reported in literature for these dyes. We also demonstrate the applicability of
the system to FLIM studies in cellular specimens including stained pollen
grains and fibroblast cells expressing green fluorescent protein. The lifetime
values obtained matched well with those reported earlier by other groups for
these same specimens. Potential applications of the present system include the
measurement of intracellular physiology and Fluorescence Resonance Energy
Transfer (FRET) imaging which are discussed in the context of live cell
imaging
Concomitant CIS on TURBT does not impact oncological outcomes in patients treated with neoadjuvant or induction chemotherapy followed by radical cystectomy
© Springer-Verlag GmbH Germany, part of Springer Nature 2018Background: Cisplatin-based neoadjuvant chemotherapy (NAC) for muscle invasive bladder cancer improves all-cause and cancer specific survival. We aimed to evaluate whether the detection of carcinoma in situ (CIS) at the time of initial transurethral resection of bladder tumor (TURBT) has an oncological impact on the response to NAC prior to radical cystectomy. Patients and methods: Patients were identified retrospectively from 19 centers who received at least three cycles of NAC or induction chemotherapy for cT2-T4aN0-3M0 urothelial carcinoma of the bladder followed by radical cystectomy between 2000 and 2013. The primary and secondary outcomes were pathological response and overall survival, respectively. Multivariable analysis was performed to determine the independent predictive value of CIS on these outcomes. Results: Of 1213 patients included in the analysis, 21.8% had concomitant CIS. Baseline clinical and pathologic characteristics of the âCISâ versus âno-CISâ groups were similar. The pathological response did not differ between the two arms when response was defined as pT0N0 (17.9% with CIS vs 21.9% without CIS; p = 0.16) which may indicate that patients with CIS may be less sensitive to NAC or †pT1N0 (42.8% with CIS vs 37.8% without CIS; p = 0.15). On Cox regression model for overall survival for the cN0 cohort, the presence of CIS was not associated with survival (HR 0.86 (95% CI 0.63â1.18; p = 0.35). The presence of LVI (HR 1.41, 95% CI 1.01â1.96; p = 0.04), hydronephrosis (HR 1.63, 95% CI 1.23â2.16; p = 0.001) and use of chemotherapy other than ddMVAC (HR 0.57, 95% CI 0.34â0.94; p = 0.03) were associated with shorter overall survival. For the whole cohort, the presence of CIS was also not associated with survival (HR 1.05 (95% CI 0.82â1.35; p = 0.70). Conclusion: In this multicenter, real-world cohort, CIS status at TURBT did not affect pathologic response to neoadjuvant or induction chemotherapy. This study is limited by its retrospective nature as well as variability in chemotherapy regimens and surveillance regimens.Peer reviewedFinal Accepted Versio
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