Logistic Supply Chain Management and Economic Security of the Enterprise

Abstract- In recent years, the interdisciplinary research of supply chains and economic security has received extensive, yet gradual, attention; when compared to the rapid economic growth of the service industry, however, sustainable supply chain management has not been systematically explored yet. The security issue in supply chains is among the most pressing concerns that firms are currently facing. So the purpose of this article is to formalize the process of interaction between an enterprise and suppliers of components necessary for the production of products. The process is considered from the point of view of determining the best conditions for the operation of the enterprise under which the production of all planned products is ensured and the costs of the enterprise for the acquisition of components necessary for the production are minimized. The model reflects the unambiguous dependence of purchases on the range and volume of output. Typically, when simulating supply chain processes, the emphasis is on managing the inventory of components of one item on the one hand or on minimizing the cost of shipping only one component. With this approach, the costs of the enterprise as a whole usually fall out of consideration. The proposed economic and mathematical model establishes a close interdependence between the proceeds from the sale of products and the costs of acquiring the components necessary for the production, between the capabilities of suppliers and the needs of the enterprise, in a supply chain model. In this model, emphasis is placed on ensuring the reliability of supplies, their magnitude and timeliness, which should be stipulated in contracts for the supply of necessary components. The model implicitly takes into account the presence of accounts payable, which may affect the amount of funds allocated for the purchase of components necessary for the production. The advantages of the model should also include accounting for the availability of components at the time of procurement. As an additional effect of the application of the model, the possibility of minimizing working capital through the implementation of a sound logistics policy based on existing working capital and their use to ensure timely delivery in the required volumes of components is considered. The supply chain ensures the economic security of the enterprise. The effective use of working capital contributes to an increase in the profitability of the enterprise and, as a result, to an increase in the income of the owner

A study of Traveling Ionospheric Disturbances and Atmospheric Gravity Waves using EISCAT Svalbard Radar IPY-data

We present a statistical study of Traveling Ionospheric Disturbances (TIDs) as observed by the EISCAT Svalbard Radar (ESR) during the continuous IPY-run (March 2007–February 2008) with field-aligned measurements. We have developed a semi-automatic routine for searching and extracting Atmospheric Gravity Wave (AGW) activity. The collected data shows that AGW-TID signatures are common in the high-latitude ionosphere especially in the field-aligned ion velocity data (244 cases of AGW-TID signatures in daily records), but they can be observed also in electron density (26 cases), electron temperature (12 cases) and ion temperature (26 cases). During the IPY campaign (in solar minimum conditions) AGW-TID events appear more frequently during summer months than during the winter months. It remains still as a topic for future studies whether the observed seasonal variation is natural or caused by seasonal variation in the performance of the observational method that we use (AGW-TID signature may be more pronounced in a dense ionosphere). In our AGW-TID dataset the distribution of the oscillation periods has two peaks, one around 0.5–0.7 h and the other around 1.1–1.3 h. The diurnal occurrence rate has a deep minimum in the region of magnetic midnight, which might be partly explained by irregular auroral activity obscuring the TID signatures from our detection routines. As both the period and horizontal phase speed estimates (as derived from the classical AGW dispersion relation) show values typical both for large scale TIDs and mesoscale TIDs it is difficult to distinguish whether the generator for high-latitude AGW-TIDs resides typically in the troposphere or in the near-Earth space. The results of our statistical analysis give anyway some valuable reference information for the future efforts to learn more about the dominating TID source mechanisms in polar cap conditions, and to improve AGW simulations

Modelling of the Supply Chain Planning for the Business and Economic Security

Abstract— Strategic supply-chain planning that combines aspects of business-strategy formulation with aspects of tactical supply-chain planning can make each far more valuable to the planning effort than either would be alone. The purpose of this article is to assess the economic security of the enterprise in terms of the efficiency of the use of supply chain planning, taking into account the possibility of production and sale of manufactured products. In case of falling demand for products, there are free capacities in the enterprise, which are useful to use to organize the production of additional items. Underutilization of the enterprise leads to higher costs, lower profitability and lower revenues, thus reducing the interest of the owners in the enterprise and thus threatening its existence. The article proposes a system of mathematical models, which allows to effectively use the capacity of the enterprise to increase its profitability due to the self-contained production of additional nomenclature, due to the use of temporarily increasing capacity. As the main hypothesis in the construction of the model, it is assumed that the economic security of the enterprise is determined by the degree of satisfaction of the economic interests of persons interested in the results of its activities. Therefore, it is proposed to consider the economic security of the enterprise from the point of view of effective use of the assets of the enterprise, which creates prerequisites for timely and full fulfilment of mutual obligations by the enterprise on the one hand, and by the owner, personnel, clients, partners, the State on the other. The proposed system of mathematical models implies that the enterprise is oriented towards the production of mass products, the realization of which involves a certain risk. The model assumes that the enterprise produces several types of industrial nomenclature and has the possibility to organize the production of additional nomenclature using available free capacities. The proposed model is intended to assess the feasibility of production, determine the best value for money and thereby increase the profitability of the enterprise. The use of a system of models improves the current activities of the enterprise, the feasibility and effectiveness of the existing innovation policy for the renewal of the production programme. The article provides recommendations for practical use of the model.

Hydrodynamic Instability of the Flux-antiflux Interface in Type-II Superconductors

The macroturbulence instability observed in fluxline systems during remagnetization of superconductors is explained. It is shown that when a region with flux is invaded by antiflux the interface can become unstable if there is a relative tangential flux motion. This condition occurs at the interface when the viscosity is anisotropic, e.g., due to flux guiding by twin boundaries in crystals. The phenomenon is similar to the instability of the tangential discontinuity in classical hydrodynamics. The obtained results are supported by magneto-optical observations of flux distribution on the surface of a YBCO single crystal with twins.Comment: 12 pages, 3 figures, submitted to Physical Review Letter

Screening properties of Gaussian electrolyte models, with application to dissipative particle dynamics

We investigate the screening properties of Gaussian charge models of electrolyte solutions by analysing the asymptotic behaviour of the pair distribution functions. We use a combination of Monte-Carlo simulations with the hyper-netted chain integral equation closure, and the random phase approximation, to establish the conditions under which a screening length is well defined and the extent to which it matches the expected Debye length. For practical applications, for example in dissipative particle dynamics, we are able to summarise our results in succinct rules-of-thumb which can be used for mesoscale modeling of electrolyte solutions. We thereby establish a solid foundation for future work, such as the systematic incorporation of specific ion effects.Comment: 9 pages, 9 figures, 1 table, RevTeX4-

Синтез та антимікробна активність 1-алкіл-5-метил-3-феніл-6-(5-феніл-1,3,4-оксадіазол-2-іл)тієно[2,3-d]піримідин-2,4(1H,3H)-діонів

An effective approach for synthesis of 5-methyl-3-phenyl-6-(5-phenyl-1,3,4-oxadiazol-2-yl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione by 1,1’-carbonyldiimidazole promoted interaction of 5-methyl-2,4-dioxo-3-phenyl-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidine-6-carboxylic acid with benzohydrazide has been developed. The procedure also includes cyclization of N’-benzoyl-5-methyl-2,4-dioxo-3-phenyl-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidine-6-carbohydrazide obtained by boiling in phosphorous oxychloride and further hydrolysis of the chlorine atom at position 2 of the thieno[2,3-d]pyrimidine system. Alkylation of the assembly of two heterocyclic units obtained with benzyl chlorides, chloroacetamides, and 5-(chloromethyl)-3-aryl-1,2,4-oxadiazoles has allowed obtaining of 1-alkyl-5-methyl-3-phenyl-6-(5-phenyl-1,3,4-oxadiazol-2-yl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-diones. The structures of the compounds obtained have been confirmed by the 1H NMR, chromato-mass spectral and elemental microanalysis data. The results of the screening performed by the agar diffusion method (“well method”) have shown the absence of the antimicrobial activity for 1-benzyl-5-methyl-3-phenyl-6-(5-phenyl-1,3,4-oxadiazol-2-yl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-diones and 2-[5-methyl-2,4-dioxo-3-phenyl-6-(5-phenyl-1,3,4-oxadiazol-2-yl)-3,4-dihydrothieno[2,3-d]pyrimidin-1(2H)-yl]-N-arylacetamides; but the activity for 1-{[3-aryl-1,2,4-oxadiazol-5-yl]methyl}-5-methyl-3-phenyl-6-(5-phenyl-1,3,4-oxadiazol-2-yl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-diones has been found. The compounds of this range appeared to be active against the strains of Staphylococcus aureus, Escherichia coli and Bacillus subtilis; the diameters of their growth inhibition zones were similar to those for the reference drugs Metronidazole and Streptomycin.Разработан эффективный подход к синтезу 5-метил-3-фенил-6-(5-фенил-1,3,4-оксадиазол-2-ил)тиено[2,3-d]пиримидин-2,4(1H,3H)-диона путем промотированного 1,1’-карбонилдиимидазолом взаимодействия 5-метил-2,4-диоксо-3-фенил-1,2,3,4-тетрагидротиено[2,3-d]пиримидин-6-карбоновой кислоты с бензогидразидом. Процедура также включает циклизацию полученного N’-бензоил-5-метил-2,4-диоксо-3-фенил-1,2,3,4-тетрагидротиено[2,3-d]пиримидин-6-карбогидразида кипячением в хлорокиси фосфора и дальнейший гидролиз атома хлора в положении 2 тиено[2,3-d]пиримидиновой системы. Алкилирование полученного двухзвенного ансамбля гетероциклов бензилхлоридами, хлорацетамидами и 5-(хлорметил)-3-арил-1,2,4-оксадиазолами позволило получить 1-алкил-5-метил-3-фенил-6-(5-фенил-1,3,4-оксадиазол-2-ил)тиено[2,3-d]пиримидин-2,4(1H,3H)-дионы. Структуры полученных соединений были подтверждены на основе данных 1Н ЯМР, хроматомас спектров и элементного анализа. По результатам скрининга методом диффузии в агар («метод колодцев») установлено отсутствие противомикробной активности у 1-бензил-5-метил-3-фенил-6-(5-фенил-1,3,4-оксадиазол-2-ил)тиено[2,3-d]пиримидин-2,4(1H,3H)-дионов и 2-[5-метил-2,4-диоксо-3-фенил-6-(5-фенил-1,3,4-оксадиазол-2-ил)-3,4-дигидротиено[2,3-d]пиримидин-1(2H)-ил]-N-арилацетамидов, а также наличие противомикробной активности для 1-{[3-арил-1,2,4-оксадиазол-5-ил]метил}-5-метил-3-фенил-6-(5-фенил-1,3,4-оксадиазол-2-ил)тиено[2,3-d]пиримидин-2,4(1H,3H)-дионов. Данные вещества проявили противомикробную активность к штаммам Staphylococcus aureus, Escherichia coli и Baсillus subtilis со значениями зон задержки роста, близкими к препаратам сравнения метронидазолу и стрептомицину.Розроблено ефективний підхід до синтезу 5-метил-3-феніл-6-(5-феніл-1,3,4-оксадіазол-2-іл)тієно[2,3-d]піримідин-2,4(1H,3H)-діону шляхом промотованої 1,1’-карбонілдіімідазолом взаємодії 5-метил-2,4-діоксо-3-феніл-1,2,3,4-тетрагідротієно[2,3-d]піримідин-6-карбонової кислоти з бензогідразидом. Процедура також включає наступну циклізацію отриманого N’-бензоїл-5-метил-2,4-діоксо-3-феніл-1,2,3,4-тетра-гідротієно[2,3-d]піримідин-6-карбогідразиду кип’ятінням у хлорокисі фосфору та подальший гідроліз атома хлору у положенні 2 тієно[2,3-d]піримідинової системи. Алкілювання отриманого дволанкового ансамблю гетероциклів бензилхлоридами, хлороацетамідами та 5-(хлорометил)-3-арил-1,2,4-оксадіазо-лами дозволило отримати 1-алкіл-5-метил-3-феніл-6-(5-феніл-1,3,4-оксадіазол-2-іл)тієно[2,3-d]піримі-дин-2,4(1H,3H)-діони. Структури отриманих сполук були підтверджені на основі даних 1Н ЯМР, хроматомас спектрів та елементного аналізу. За результатами скринінгу методом дифузії в агар («метод колодязів») встановлено відсутність антимікробної активності у 1-бензил-5-метил-3-феніл-6-(5-феніл-1,3,4-оксадіазол-2-іл)тієно[2,3-d]піримідин-2,4(1H,3H)-діонів та 2-[5-метил-2,4-діоксо-3-феніл-6-(5-феніл-1,3,4-оксадіазол-2-іл)-3,4-дигідротієно[2,3-d]піримідин-1(2H)-іл]-N-арилацетамідів, а також наявність антимікробної активності для 1-{[3-арил-1,2,4-оксадіазол-5-іл]метил}-5-метил-3-феніл-6-(5-феніл-1,3,4-окса-діазол-2-іл)тієно[2,3-d]піримідин-2,4(1H,3H)-діонів. Дані речовини виявили антимікробну активність до штамів Staphylococcus aureus, Escherichia coli та Baсillus subtilis із значеннями зон затримки росту, близькими до препаратів порівняння метронідазолу та стрептоміцину

Interaction between superconducting vortices and Bloch wall in ferrite garnet film

Interaction between a Bloch wall in a ferrite-garnet film and a vortex in a superconductor is analyzed in the London approximation. Equilibrium distribution of vortices formed around the Bloch wall is calculated. The results agree quantitatively with magneto-optical experiment where an in-plane magnetized ferrite-garnet film placed on top of NbSe2 superconductor allows observation of individual vortices. In particular, our model can reproduce a counter-intuitive attraction observed between vortices and a Bloch wall having the opposite polarity. It is explained by magnetic charges appearing due to discontinuity of the in-plane magnetization across the wall.Comment: 4 pages, 5 figure

Double bracket dissipation in kinetic theory for particles with anisotropic interactions

We derive equations of motion for the dynamics of anisotropic particles directly from the dissipative Vlasov kinetic equations, with the dissipation given by the double bracket approach (Double Bracket Vlasov, or DBV). The moments of the DBV equation lead to a nonlocal form of Darcy's law for the mass density. Next, kinetic equations for particles with anisotropic interaction are considered and also cast into the DBV form. The moment dynamics for these double bracket kinetic equations is expressed as Lie-Darcy continuum equations for densities of mass and orientation. We also show how to obtain a Smoluchowski model from a cold plasma-like moment closure of DBV. Thus, the double bracket kinetic framework serves as a unifying method for deriving different types of dynamics, from density--orientation to Smoluchowski equations. Extensions for more general physical systems are also discussed.Comment: 19 pages; no figures. Submitted to Proc. Roy. Soc.

Computer Microscopy of Biological Fluid Dry Patterns for Medical Diagnostics

We elaborate hardware and software system that implements the principle of diagnosis based on the standard procedure of pattern preparation including digital recognition of image and its computer analysis based on specially developed algorithms by comparing with the expert descriptors and extensive database of dry pattern samples obtained from clinical treatments which include more than 1500 samples to high selective and accuracy recognition of pathologies, for recognition of wide range of pathologies, in particular, the endogenous intoxication. Keywords: biological fluids, image analysis, medical diagnostics, endogenous intoxication