Real estate brokers: do they inflate housing prices? The case of France.

This study examines the impact of real estate brokers on the price of residential properties sold in 2005 in twelve French cities. The results indicate that brokers increase the prices of properties they sell even though they appear to have heterogeneous behaviours across cities. The impact of brokers also varies by property size and age of clients. One and two room apartments have higher selling prices when sold through brokers. Buyers in their thirties and forties who seek the assistance of brokers pay more for their homes whereas older sellers obtain higher prices from broker intermediation.Real estate brokers; Broker intermediation; Price; France;

Urgency Public Data Protection Based on Data Leakage Cases at The Indonesian Child Protection Commission

Privacy is the essential thing regulated in Human Rights. As a country that recognizes human rights, Indonesia is a state that adheres to the principles of human rights and also recognizes that privacy is a human right that the state must protect. However, no law addresses the issue of public data protection in Indonesia comprehensively. On Monday, October 18, 2021, data leaks on the identity of the complainant and underage victim, case summary, and mediation results were found. It has at least two significant impacts, firstly it can impact the inhibition of KPAI's performance due to public trust, and secondly, it will have a worse impact on victims and whistleblowers, both physically and mentally, because this can trigger predatory movement. The research method used is normative legal research based on secondary data library research which is descriptive, evaluative, and prescriptive. Several approaches are used, namely the legal and conceptual approach, in an attempt to answer the first question, the point of contact between an individual and state interest, and a comparative approach to answer the second problem regarding the dynamics of personal data protection arrangements in the problem of data leakage experienced by KPAI. Therefore, Indonesia needs to immediately legitimate the Draft Law on Public Data Protection (RUU PDP) so that the urgency of the legalization of public data protection can be immediately resolved

Time-of-Day Effects on Younger and Older Adult Executive Functioning

The most recent time-of-day (TOD) body of research has explored how TOD effects can influence certain cognitive domains such as semantic memory, episodic memory, processing speed, and executive functioning (Allen et al., 2008). Research by Horne and Ostberg (1976) has shown how differences in age can be associated with a preference for a certain TOD (i.e., morning or afternoon). Seventy-five percent of adults 65 years or older tend to prefer the morning, whereas fewer than 10 of younger adults tend to prefer the afternoon (Horne & Ostberg, 1976 West et al., 2002). Research by Allen and colleagues (2008) has shown how performance on certain tasks related to assessing different cognitive domains can be influenced by TOD effects (Allen et al., 2008 Intons-Peterson, Rocci, West, McLellan, & Hackney, 1998 May & Hasher, 1998 May, Hasher, & Stoltzfus, 1993). The adult western society has tended to focus on morning performance however, the opposite effect is seen for younger adults. Morning performance has been found to be slightly impaired for younger adults when compared to older adult performance in the morning, and younger adults have shown the greatest advantage on tasks performed in the afternoon, when compared to older adults. To date, research has not examined the effects from TOD using a comprehensive and standardized measure of executive functioning (i.e., The Delis-Kaplin Executive Function System or D-FEFS) to compare difference in younger and older adult performance. The current study was intended to extend on the Allen et al. research and examine younger and older adult performance on executive functioning when they are tested at their preferred TOD or less preferred TO

Screening for genetic modifiers of dawdle in Arabidopsis [abstract]

Faculty Mentor: John Walker, Biological SciencesThe Arabidopsis mutant dawdle (ddl) exhibits slow growth. In addition, ddl mutants have smaller rosette leaves, and the leaves are curled and the overall stature of the plant is reduced. Mutant plants also display short roots, delayed flowering time, altered floral organ numbers, defective floral organs, and reduced fertility. DDL encodes a protein with a FHA (fork-headed associated) interaction domain that may function as a positive regulator of cell proliferation, similar to other characterized FHA domain proteins of animal and yeast cells. However, the molecular mechanism of action of DDL is still unclear. We hypothesized that we can identify other genes relevant to DDL function by identifying genetic modifiers of ddl. The experimental approach chosen for this project was activation tagging. Over 6000 plants were ddl plants were grown and were inoculated with Agrobacterium harboring the activation tagging construct and allowed to self-fertilize. The seeds were harvested, planted and Basta herbicide was topically applied to select for the transgenic plants. The seeds from putative genetic modifiers will be collected and re-screened for the phenotype. This approach may identify proteins that affect cell proliferation or interact with DDL, and they should help us to better understand the molecular basis for plant growth and development.MU Monsanto Undergraduate Research Fellowshi

Heimatmuseum Bezau. A Building Extension In The Bregenzerwald

Abweichender Titel nach Übersetzung der Verfasserin/des VerfassersEin Erweiterungsbau im Bregenzerwald. Inhalt dieser Arbeit ist die Auseinandersetzung mit dem Heimatmuseum Bezau ein typisches Bauernhaus des Hinteren Bregenzerwaldes. Konkret handelt es sich um ein erweitertes Seitenflurhaus aus dem späten 17. Jahrhundert mit einem Wohntrakt nach Süden und einem ursprünglichen Wirtschaftsteil nach Norden. Mensch und Tier bzw. Wohnen und Arbeiten befinden sich bei dieser Typologie unter einem Dach. Wer mit den, für gewöhnlich langgestreckten, typischen Bregenzerwälderhäusern vertraut ist, wird schnell die eigenartige, fast befremdliche Proportion des Hauses bemerken. Die Transformation fand vor rund hundert Jahren statt, als das Hinterhaus aufgrund von Baumängeln nicht mehr erhaltenswert war. So formte sich der einst langgestreckte Körper zu einem quadratischen Volumen, das eingebettet in der Landschaft ruht. Der bestehende, umfunktionierte Wohntrakt dient seither als Heimatmuseum. Das Museum zieht viele Besucher an und gibt einen guten Einblick in die regionale Wohnund Lebenskultur des letzten Jahrhunderts. Allerdings fehlen dem Haus wichtige Räumlichkeiten, die Platz bieten für Verwaltung, Depot und Restaurierungsarbeiten sowie Veranstaltungsmöglichkeiten. Daraus resultierten der Wunsch und das Bedürfnis, mich mit einem Entwurf für einen Erweiterungsbau des Museums zu beschäftigen. Ziel ist es, einen Dialog zwischen Alt und Neu entstehen zu lassen den Neubau möglichst sensibel zu platzieren und dabei den Bedürfnissen des Altbestandes gerecht zu werden.A Building Extension In The Bregenzerwald. This document is a discussion about the local museum in Bezau a typical old farmhouse in the Bregenzerwald. To be more specific, the building is an extended „Seitenflurhaus“ from the late 17th century with a residential tract to the south and a formerly occupational section to the north. Due to the typology of these houses, the living and working areas are in one building, so the humans and the animals live under one roof. About a hundred years ago, the occupational section of today‘s local museum was demolished due to construction defects. Finally, the remaining residential part was transformed into the local museum of Bezau. Thus, today the once elongated body has been transformed into a square space, which seems rather unusual for this typology. The museum attracts numerous visitors and provides good insight into the living conditions during the last century. Today, the house lacks important rooms, which would offer space for administration, storage and restoration work as well as for events. This is what lead to my desire and the need to work on a design for an extension building. The aim is to create a dialogue between the old and the new sections to place the new building as sensitively as possible and to meet the requirements of the old existing building.19

Sigma1 and Sigma2 binding studies of novel receptor ligands [abstract]

Abstract only availableSigma receptors are studied due to their presence both in the central nervous system and also in human tumors of neural origin. There are two types of sigma receptors: sigma1 and sigma2. Sigma1 receptors may be involved with diseases such as schizophrenia, dementia, ischemia, and some peripheral nervous system diseases. Sigma2 receptor expression may be indicative of the proliferative status of certain cancers. We are studying structural analogs of a sigma1 selective agonist, 1-(3',4'-dimethoxyphenethyl)-4-(3''-phenylpropyl)piperazine, developed by Santen Pharmaceutical Co. This compound is commonly referred to as SA 4503. We tested 7 novel compounds in order to see how their structural differences affect their affinity for sigma1 and sigma2 receptors. The technique used is referred to as a radioreceptor binding assay. Experiments were conducted using 10 inhibitor concentrations of test ligands in membranes (0.25 mg/ml protein) prepared from guinea pig brains in TRIS-HCl buffers (50 mM; pH 7.4, 25 degrees, sigma1; pH 8.0, 25 degrees, sigma2). Sigma1 assays used [3H]-pentazocine ([3H]-PTZ; 1.0 nM) at 37 degrees for 150 min with haloperidol (1.0 uM) to define non-specific binding. The sigma2 assays used [3H]-ditolylguanidine ([3H]-DTG; 3.0 nM) at 25 degrees for 120 min with DTG (100 uM) to define non-specific binding. The sigma2 assays were run in the presence of cold (+)-PTZ (200 nM) to mask sigma1 sites. Inhibition data and statistics for model fits were analyzed by non-linear, least-squares regression using the KELL (Biosoft) and Prism (GraphPad) suite of programs. Apparent affinity (Ki) values ranged from 1.75 +/- 0.17 nM to 30.13 +/- 1.24 nM for sigma1 sites, and from 6.75 +/- 0.20 nM to 113.2 +/- 11.7 nM for sigma2 sites. The findings may aid in the development of structure activity relationships allowing the design of ligands selective for one or the other of the sigma receptor types.Molecular Imaging Progra