Variability in yield traits of TILLING population of bread wheat (Triticum aestivum L.)

Mutagenesis is one of the powerful genetic strategies for crop improvement programmes. A chemically induced mutated genetic resource for detecting novel variations by Targeting Induced Local Lesions IN Genomes (TILLING) has been developed in recently released bread wheat (Triticum aestivum) cultivar DPW621-50. A total of 3,478 M2 plants were evaluated for plant height, number of tillers/plant, thousand grain weight, number of seeds/spike and grain yield/plant. A large variation was observed for all the traits. The highest frequency (52.2%) of lines had similar height between 91-100 cm to the non-mutagenized DPW 621-50 control followed by 28.9% of lines with height between 81-90 cm. A large variation was observed in number of tillers/plant which ranged from 1-35 tillers/plant. The highest frequency (32.09%) lines had 31-40 seeds/spike followed by 29.84% lines with 41-50 seeds/spike. Few lines (0.35%) had more than 70 seeds/spike with normal seed size as their thousand grain weight ranged between 34.82-43.82g. Chlorophyll deficient, grassy type and sterile mutants were also observed. This population may serve as new genetic resource for functional genomics studies and novel variants for different traits in elite germplasm can be made available to the plant breeders for wheat improvement

Effect of Solvent on of 4- Phenyl-7-Hydroxy Coumarin - P –Chloro Anilide

The absorption and fluorescence emission spectra of 4- phenyl-7-hydroxy Coumarin - p-chloroanilide have been reported in various polar and non polar solvents. The increase in solvent polarity shows the increase in absorption and emission wave length i.e ???* transition. This indicates the value of excited state dipole moments can’t be calculated using the solvatochromic data. The results are explained in terms of bathochromomic-shift, and possibility of hydrogen bonding

Clinical profile of dengue patients: A hospital based study

Context: For most of the patients, dengue is a self-limiting viral fever, but in some patients, it results in a life threatening conditioncalled as dengue hemorrhagic fever or dengue shock syndrome. Objective: We attempted to determine the common and atypicalclinical and laboratory features in children suffering from dengue fever, which will help in early diagnosis and management of patientssuffering from dengue infection. Design: Hospital based descriptive, cross-sectional study conducted from January 2014 to December2014. Setting: Tertiary referral teaching hospital. Patients: All patients between 1-month and 12 years admitted in pediatric ward withsymptoms suggestive of dengue and who turn out to be positive for NS1 antigen alone or NS1 and immunoglobulin M antibody againstdengue were included in the study. Data regarding relevant history and clinical examination and outcome and relevant investigationswere collected. Results: Of 250 children included in the study, 145 (58%) were male and 105 (42%) were female. The most commonpresenting complaint was fever (92.8%), followed by abdominal pain (46.4%). The most common clinical sign was pyrexia followedby relative bradycardia (37.6%) and hypotension (26.4%). On laboratory investigation, the most common abnormality detected wasleucopenia (81.6%) followed by thrombocytopenia (69.2%). Conclusion: A high index of suspicion is required on the part of treatingpediatrician to diagnose dengue early and treat accordingly to prevent mortality due to dengue

On the Thermodynamic Geometry of Hot QCD

We study the nature of the covariant thermodynamic geometry arising from the free energy of hot QCD. We systematically analyze the underlying equilibrium thermodynamic configurations of the free energy of 2- and 3-flavor hot QCD with or without including thermal fluctuations in the neighborhood of the QCD transition temperature. We show that there exists a well-defined thermodynamic geometric notion for QCD thermodynamics. The geometry thus obtained has no singularity as an intrinsic Riemannian manifold. We further show that there is a close connection of this geometric approach with the existing studies of correlations and quark number susceptibilities in hot QCD.Comment: 15 pages, 12 figures, Keywords: Thermodynamic Geometry, Hot QCD, Quasi-particles, PACS: 12.38.-t; 05.70.Fh; 02.40.Ky; 12.40.E

Utilization of chlorophyll content index (CCI) to infer yellow rust severity in wheat (Triticum aestivum L.)

Stripe rust caused by Puccinia striformis Westend. f. sp. tritici Eriks. (Pst) is a major constraint to wheat production in Northern India. In this study, 616 indigenous germplasm (IC) accessions of wheat were screened under field conditions against mixture of Pst isolates at DWR Karnal during 2012-13 crop season. Out of 616 accessions, 197 accessions were observed to be resistant (R), 115 moderately resistant (MR) to moderately susceptible (MS) and 304 as susceptible (S) against yellow rust. On the basis of days to heading, the accessions were grouped into four classes (early, medium early, medium late and late). Chlorophyll content index (CCI) recorded in flag leaf showed significant differences between resistant and susceptible lines in each classified group at 5% level of significance. The difference for CCI between resistant and moderately resistant plants was negligible, however in comparison with resistant plants, susceptible plants showed loss of 35-39% of chlorophyll. There was negative correlation (a correlation coefficient of – 0.60) between chlorophyll content and disease severity due to stripe rust in susceptible accessions

Safe Water – Is it really Safe?

Entering into the new field of business is not an easy go. One has to do market research, to identify the gap, to identify the product/service to be offered, and to target the right customer segment. After doing the required research, the next step is to make decisions on plant location, layout and then set up.  Assessment of funds required for capital as well as revenue expenditure, procurement of machinery and other materials also take substantial amount of efforts. Searching for vendors and finalizing the right one are few other issues. After having worked successfully for more than 30 years in Bali in the field of sesame seeds and oil business Harsh was standing on a crossroad in 2011. Rising prices of sesame oil resulted in shift in customers’ taste and preferences towards refined oil. Moreover entry of big players at a large scale of operations and rise in price of raw material (sesame seeds) made survival tough. He had a number of options, one to continue with existing business at different scale of operations. Two, enter another business? Three, what business, Four, which place? The case talks about Harsh’s journey to new business, his choice and then the result

Nucleic acid drugs: a novel approach

Nucleic acid base sequence of proteins plays a crucial role in the expression of gene. The gene is responsible for the synthesis of proteins and these proteins, which are synthesized, are responsible for the biological process and also for dreadful diseases as well. Once if the nucleic acid sequence is altered, we would be able to block or transfer the message for protein synthesis, there by preventing the particular protein, which is responsible for the disease. These nucleic acids act as drugs by different mechanisms, they may bind with the synthesized proteins, and they can hybridize to a messenger RNA leading to translation arrest or may induce degradation to target RNA. In this way the nucleic acids act as drug for inhibiting gene expression or protein synthesis. This article examines about the different types of nucleic acid drugs, their mechanisms, advantages, drawbacks and their future prospects. Key Words: Aptamers, ribozymes, antisense oligonucleotides. African Journal of Biotechnology Vol.3(12) 2004: 662-66

Dihetero double Michael addition in PEG-400: Synthesis of 2,3-dihydro- [2,3-c]-[1,2,4]-triazole scaffold

1586-1592Potassium carbonate in poly (ethylene glycol-400) has been found to be a highly effective and efficient medium for the straight forward, convenient, one pot and green synthesis of diethyl/ethyl cyano-5-[substituted phenyl-2,3-dihydro-[1,3,4]-thiadiazolidino - [2, 3-c] – [1, 2, 4]-triazol -2- yl] – malonate/acetate through intramolecular cyclo- elimination of Michael adducts formed between the reaction of 4-amino-5- substituted phenyl-3-mercapto-1,2,4-triazole 1 with diethyl-2-(ethoxymethylene) malonate and ethyl -2-cyano-3-ethoxyacrylate respectively. The structures of all the new compounds have been elucidated using IR, 1H and 13C NMR, mass spectral data and elemental analyses

Dihetero double Michael addition in PEG-400: Synthesis of 2,3-dihydro- [2,3-c]-[1,2,4]-triazole scaffold

Potassium carbonate in poly (ethylene glycol-400) has been found to be a highly effective and efficient medium for the straight forward, convenient, one pot and green synthesis of diethyl/ethyl cyano-5-[substituted phenyl-2,3-dihydro-[1,3,4]-thiadiazolidino - [2, 3-c] – [1, 2, 4]-triazol -2- yl] – malonate/acetate through intramolecular cyclo- elimination of Michael adducts formed between the reaction of 4-amino-5- substituted phenyl-3-mercapto-1,2,4-triazole 1 with diethyl-2-(ethoxymethylene) malonate and ethyl -2-cyano-3-ethoxyacrylate respectively. The structures of all the new compounds have been elucidated using IR, 1H and 13C NMR, mass spectral data and elemental analyses.