San Rocco/Koromačnik military camps (2nd–1st centuries BC)

On the San Rocco hill, remote sensing and field-walking campaigns indicated the existence of a large Roman military camp (Camp 1) extending over the whole area, a small camp on the top of the hill (Camp 2), and a large area south of it where orthogonal structures have been identified. To clarify the function and chronology of the remains, three trenches were opened in 2019 and 2021. Part of a terrace construction dated between the end of the 2nd and mid-1st century BC was found in Trench 1. Together with orthogonal crop and shadow marks, it indicates that a large part of the hill was arranged in terraces. The northern rampart of Camp 1 was excavated in Trench 3. The 6.5-m-wide fortification of Phase 1 consisted of four lines of defence combining a low stone wall with a wooden superstructure, protected by a palisade, two lines of wooden obstacles, and a stone escarpment. The structure, dated to the 2nd century BC, was destroyed by a fire and restored by adding an earth bank in Phase 2 (end of the 2nd or beginning of the 1st century BC). Camp 2 on the top of the hill was protected by a low walkway that consisted of an earth rampart reinforced on the inside by a row of stones and on the outside by a stone accumulation (Trench 2). Its construction in Phase 1 is dated into the pre-Caesarean period and the renovation in Phase 2 into the mid-1st century BC

Decifrare e cartografare le tracce del paesaggio antico nel Carso triestino

The extensive analysis of remote-sensed data (among which ALS-derived images) and fieldwork carried out in the Trieste Karst (Northeastern Italy) have shed light on archaeological landscapes largely unknown until recent years. The chronological definition of this complex palimpsest was based on the collection of findings associ-ated to the archeological evidence, shape and orientation of detected structures and stratigraphic relations among features. This allowed to evaluate the interplay between archaeological and geo-morphological landforms through time and to reconstruct some long-term economic strategies pursued by past communities. As a result, we present a map of the easternmost sector of the Trieste area, next to the border between Italy and Slovenia, approximately corresponding to the area of the map Carta Tecnica Regionale “Grozzana”. The map aims at providing a tool for the protection of the cultural and envi-ronmental heritage, land use planning and touristic valorisation of the area

Abdominal versus perineal approach for external rectal prolapse: systematic review with meta-analysis

External rectal prolapse; SurgeryProlapso rectal externo; CirurgíaProlapse rectal extern; CirurgiaBackground External rectal prolapse (ERP) is a debilitating condition in which surgery plays an important role. The aim of this study was to evaluate the outcomes of abdominal approaches (AA) and perineal approaches (PA) to ERP. Methods This was a PRISMA-compliant systematic review with meta-analysis. Studies published between 1990 and 2021 were retrieved. The primary endpoint was recurrence at the last available follow-up. Secondary endpoints included factors associated with recurrence and function. All studies were assessed for bias using the Newcastle–Ottawa Scale and Cochrane tool. Results Fifteen studies involving 1611 patients (AA = 817; PA = 794) treated for ERP were included, three of which were randomized controlled trials (RCTs; 114 patients (AA = 54; PA = 60)). Duration of follow-up ranged from 12 to 82 months. Recurrence in non-randomized studies was 7.7 per cent in AA versus 20.1 per cent in PA (odds ratio (OR) 0.29, 95 per cent confidence interval (c.i.) 0.17 to 0.50; P < 0.001, I2 = 45 per cent). In RCTs, there was no significant difference (9.8 per cent versus 16.3 per cent, AA versus PA (OR 0.82, 95 per cent c.i. 0.29 to 2.37; P = 0.72, I2 = 0.0 per cent)). Age at surgery and duration of follow-up were risk factors for recurrence. Following AA, the recurrence rates were 10.1 per cent and 6.2 per cent in patients aged 65 years and older and less than 65 years of age, respectively (effect size [e.s.] 7.7, 95 per cent c.i. 4.5 to 11.5). Following PA, rates were 27 per cent and 16.3 per cent (e.s. 20.1, 95 per cent c.i. 13 to 28.2). Extending follow-up to at least 40 months increased the likelihood of recurrence. The median duration of hospital stay was 4.9 days after PA versus 7.2 days after AA. Overall, incontinence was less likely after AA (OR 0.32), but constipation occurred more frequently (OR 1.68). Most studies were retrospective, and several outcomes from RCTs were not consistent with those observed in non-RCTs. Conclusion The overall risk of recurrence of ERP appears to be higher with PA versus AA. Incontinence is less frequent after AA but at the cost of increased constipation. Age at surgery and duration of follow-up are associated with increased risk of recurrence, which warrants adequate reporting of future studies on this topic

Non-Abelian Vortices of Higher Winding Numbers

We make a detailed study of the moduli space of winding number two (k=2) axially symmetric vortices (or equivalently, of co-axial composite of two fundamental vortices), occurring in U(2) gauge theory with two flavors in the Higgs phase, recently discussed by Hashimoto-Tong (hep-th/0506022) and Auzzi-Shifman-Yung (hep-th/0511150). We find that it is a weighted projective space WCP^2_(2,1,1)=CP^2/Z_2. This manifold contains an A_1-type (Z_2) orbifold singularity even though the full moduli space including the relative position moduli is smooth. The SU(2) transformation properties of such vortices are studied. Our results are then generalized to U(N) gauge theory with N flavors, where the internal moduli space of k=2 axially symmetric vortices is found to be a weighted Grassmannian manifold. It contains singularities along a submanifold.Comment: 32 pages, 1 figure, the final version published in PR

On the moduli space of semilocal strings and lumps

We study BPS non-abelian semilocal vortices in U(Nc) gauge theory with Nf flavors, Nf > Nc, in the Higgs phase. The moduli space for arbitrary winding number is described using the moduli matrix formalism. We find a relation between the moduli spaces of the semilocal vortices in a Seiberg-like dual pairs of theories, U(Nc) and U(Nf-Nc). They are two alternative regularizations of a "parent" non-Hausdorff space, which tend to the same moduli space of sigma-model lumps in the infinite gauge coupling limits. We examine the normalizability of the zero-modes and find the somewhat surprising phenomenon that the number of normalizable zero-modes, dynamical fields in the effective action, depends on the point of the moduli space we are considering. We find, in the lump limit, an effective action on the vortex worldsheet, which we compare to that found by Shifman and Yung.Comment: 1+48 pages, 5 fig. v2 several changes to secton 6.3, sections 6.4 and 6.5 adde

Commercial hemp seed oils: a multimethodological characterization

Nine commercial hemp seed oils from different countries were studied using a multimethodological approach to obtain information about their quality and chemical composition. Due to the lack of a specific regulation for hemp seed oils, quality parameters used in the case of olive oils (free acidity, peroxides number, spectrophotometer parameters) and anisidine number were measured and compared with those reported for extra virgin olive oil (EVOO). Free acidity and peroxides number showed a great variability, ranging from 0.4 to 17.24% and from 4.32 to 22.14 meqO2/kg, respectively, whereas the anisidine number ranged from 0.11 to 3.58. K232 value turned out to be generally below the limit reported for EVOO, whereas K270 and ΔK values were higher, with respect to EVOO limits, due to the high amount of tri-unsaturated fatty chains. Colorimetric analysis showed a peculiar curve trend that could represent the fingerprint of this product. Untargeted nuclear magnetic resonance methodology allowed to measure the amount of fatty chains, ω-6:ω-3 ratio, β-sitosterol, and aldehydes. The ω-6:ω-3 ratio turned out to be, in some cases, different from that reported on the bottle labels. Finally, lipoperoxidation assays were also carried out under different storage (light and temperature) and time exposure conditions, confirming that the exposure to direct light is the condition that interferes more with the product quality

Use of the INSPIRE EF data specifications to develop the SEIS-Malta geodatabase for the air quality data management

SEIS-Malta system (Shared Environmental Information System (SEIS) and web-based GIS interface) forms part of a global project on environmental monitoring funded under the 2007- 2013 Structural Funds Programme for Malta. • The project “Developing national environmental infrastructure and capacity”, is co-financed by the European Regional Development Fund (ERDF) which provides 85% of the project’s funding and the Government of Malta, which finances the rest under Malta’s Operational Programme I - Cohesion Policy 2007- 2013 “Investing in Competitiveness for a Better Quality of Life”.peer-reviewe

Prehistoric Stone Disks from Entrances and Cemeteries of North-Eastern Adriatic Hillforts

The paper presents a group of four, approximately 0.5m large, stone disks from entrances or cemeteries of two protohistoric hillforts of north-eastern Adriatic. The disks, having a sparse chronology with the exception of one dated to the Middle Bronze Age, show flat and plain surfaces or covered with sub-circular depressions. One disk shows two larger cup-marks at the centre of both faces. They are interpreted as ritual artefacts based on the association with sacred settlement locations and comparisons with similar coeval stones found mainly close to citadel entrances, burials and thresholds in the Aegean area and Anatolia

Chemico-biological characterization of Torpedino Di Fondi® tomato fruits. A comparison with San Marzano cultivar at two ripeness stages

Torpedino di Fondi (TF) is a hybrid tomato landrace developed in Sicily and recently introduced in the south Lazio area along with the classical San Marzano (SM) cultivar. The present study aimed at characterizing TF tomatoes at both pink and red ripening stages, and at comparing them with traditional SM tomatoes. A multidisciplinary approach consisting of morphological, chemical (FT‐ICR MS, NMR, HPLC, and spectrophotometric methods), and biological (antioxidant and antifungal in vitro activity) analyses was applied. Morphological analysis confirmed the mini‐ San Marzano nature and the peculiar crunchy and solid consistency of TF fruits. Pink TF tomatoes displayed the highest content of hydrophilic antioxidants, like total polyphenols (0.192 mg/g), tannins (0.013 mg/g), flavonoids (0.204 mg/g), and chlorophylls a (0.344 mg/g) and b (0.161 mg/g), whereas red TF fruits were characterized by the highest levels of fructose (3000 mg/100 g), glucose (2000 mg/100 g), tryptophan (2.7 mg/100 g), phenylalanine (13 mg/100 g), alanine (25 mg/100 g), and total tri‐unsaturated fatty acids (13% mol). Red SM fruits revealed the greatest content of lipophilic antioxidants, with 1234 mg/g of total carotenoids. In agreement with phenolics content, TF cultivar showed the greatest antioxidant activity. Lastly, red TF inhibited Candida species (albicans, glabrata and krusei) growth

The impact of the COVID-19 pandemic on surgical management of breast cancer:global trends and future perspectives

Introduction: The rapid spread of COVID-19 across the globe is forcing surgical oncologists to change their daily practice. We sought to evaluate how breast surgeons are adapting their surgical activity to limit viral spread and spare hospital resources. Methods: A panel of 12 breast surgeons from the most affected regions of the world convened a virtual meeting on April 7, 2020, to discuss the changes in their local surgical practice during the COVID-19 pandemic. Similarly, a Web-based poll based was created to evaluate changes in surgical practice among breast surgeons from several countries. Results: The virtual meeting showed that distinct countries and regions were experiencing different phases of the pandemic. Surgical priority was given to patients with aggressive disease not candidate for primary systemic therapy, those with progressive disease under neoadjuvant systemic therapy, and patients who have finished neoadjuvant therapy. One hundred breast surgeons filled out the poll. The trend showed reductions in operating room schedules, indications for surgery, and consultations, with an increasingly restrictive approach to elective surgery with worsening of the pandemic. Conclusion: The COVID-19 emergency should not compromise treatment of a potentially lethal disease such as breast cancer. Our results reveal that physicians are instinctively reluctant to abandon conventional standards of care when possible. However, as the situation deteriorates, alternative strategies of de-escalation are being adopted. Implications for Practice: This study aimed to characterize how the COVID-19 pandemic is affecting breast cancer surgery and which strategies are being adopted to cope with the situation. © 2020 AlphaMed Pres