The European Marine Observation and Data Network (EMODnet): Visions and roles of the gateway to marine data in Europe

Marine data are needed for many purposes: for acquiring a better scientific understanding of the marine environment, but also, increasingly, as marine knowledge for decision making as well as developing products and services supporting economic growth. Data must be of sufficient quality to meet the specific users' needs. It must also be accessible in a timely manner. And yet, despite being critical, this timely access to known-quality data proves challenging. Europe's marine data have traditionally been collected by a myriad of entities with the result that much of our data are scattered throughout unconnected databases and repositories. Even when data are available, they are often not compatible, making the sharing of the information and data aggregation particularly challenging. In this paper, we present how the European Marine Observation and Data network (EMODnet) has developed over the last decade to tackle these issues. Today, EMODnet is comprised of more than 150 organizations which gather marine data, metadata, and data products and make them more easily accessible for a wider range of users. EMODnet currently consists of seven sub-portals: bathymetry, geology, physics, chemistry, biology, seabed habitats, and human activities. In addition, Sea-basin Checkpoints have been established to assess the observation capacity in the North Sea, Mediterranean, Atlantic, Baltic, Artic, and Black Sea. The Checkpoints identify whether the observation infrastructure in Europe meets the needs of users by undertaking a number of challenges. To complement this, a Data Ingestion Service has been set up to tackle the problem of the wealth of marine data that remain unavailable, by reaching out to data holders, explaining the benefits of sharing their data and offering a support service to assist them in releasing their data and making them available through EMODnet. The EMODnet Central Portal (www.emodnet.eu) provides a single point of access to these services, which are free to access and use. The strategic vision of EMODnet in the next decade is also presented, together with key focal areas toward a more user-oriented service, including EMODnet for business, internationalization for global users, and stakeholder engagement to connect the diverse communities across the marine knowledge value chain

Performance characterization of influent and effluent treatment systems: A case study at Craig Brook National Fish Hatchery

AbstractThis study characterizes the performance of influent and effluent disinfection systems at Craig Brook National Fish Hatchery, a U.S. Fish and Wildlife Service (USFWS) Atlantic salmon Salmo salar restoration facility in East Orland, ME. Influent treatment of the hatchery's water supply limits fish exposure to pathogens and protects the hatchery's goal to recover endangered Atlantic salmon. Disinfection treatment of effluent from the hatchery's wild fish receiving building ensures containment of pathogens that could be transferred to the facility with young fish captured from native rivers and protects the downstream hatchery watershed area. Evaluation of the influent treatment system consisted of assessing the effectiveness of the sand filtration and ultraviolet (UV) disinfection equipment, which are used to treat the water supply for the entire hatchery. Evaluation of the effluent treatment system examined the effectiveness of microscreen filtration and UV equipment that are used to disinfect effluent from the hatchery's wild fish-receiving building. Water samples were collected every 2 weeks for a 6-month period. The evaluation of both treatment systems indicates effective solids removal and total heterotrophic bacteria inactivation (2–4log10 reductions). No disease issues attributable to the hatchery's water supply have occurred during operation of its influent disinfection system, enabling the USFWS continued success with its restoration programs

The Janus face of Bartonella quintana recognition by Toll-like receptors (TLRs): a review.

Contains fulltext : 70849.pdf (publisher's version ) (Closed access)Bartonella quintana (B. quintana) is a facultative, intracellular bacterium, which causes trench fever, chronic bacteraemia and bacillary angiomatosis. Little is known about the recognition of B. quintana by the innate immune system. In this review, we address the impact of Toll-like receptors (TLRs) on the recognition of B. quintana and the activation of the host defense. When experimental models using human mononuclear cells, transfected CHO cells, or TLR2-/- and TLR4-/- mice were used, differential effects of TLR2 and TLR4 have been observed. B. quintana micro-organisms stimulated cytokine production through TLR2-mediated signals, whereas no role for TLR4 in the recognition of this pathogen was observed. When single, water-phenol extraction was performed, B. quintana LPS, stimulated cytokine production in a TLR2-dependent manner. However, when double extraction was performed in order to generate highly purified LPS, B. quintana LPS entirely lost its capacity to stimulate cytokines, demonstrating that non-LPS components of B. quintana are responsible for the recognition through TLR2. Moreover, B. quintana LPS was shown to be a potent antagonist of Toll-like receptor 4 (TLR4). In conclusion, B. quintana is an inducer of cytokines through TLR2-, but not TLR4-, dependent mechanisms. This stimulation is induced by bacterial components other than lipopolysaccharide. B. quintana LPS is a naturally occurring antagonist of Toll-like receptor 4 (TLR4). In view of the role played by TLR4 in inflammation, B. quintana LPS may be useful as an anti-TLR4 agent with therapeutic potential in both infections and autoimmune inflammation