Dimensional properties of the harmonic measure for a random walk on a hyperbolic group

International audienceThis paper deals with random walks on isometry groups of Gromov hyperbolic spaces, and more precisely with the dimension of the harmonic measure $\nu$ associated with such a random walk. We first establish a link of the form $\dim \nu \leq h/l$ between the dimension of the harmonic measure, the asymptotic entropy $h$ of the random walk and its rate of escape $l$. Then we use this inequality to show that the dimension of this measure can be made arbitrarily small and deduce a result on the type of the harmonic measure

Weighted One-Deterministic-Counter Automata

We introduce weighted one-deterministic-counter automata (ODCA). These are weighted one-counter automata (OCA) with the property of counter-determinacy, meaning that all paths labelled by a given word starting from the initial configuration have the same counter-effect. Weighted ODCAs are a strict extension of weighted visibly OCAs, which are weighted OCAs where the input alphabet determines the actions on the counter. We present a novel problem called the co-VS (complement to a vector space) reachability problem for weighted ODCAs over fields, which seeks to determine if there exists a run from a given configuration of a weighted ODCA to another configuration whose weight vector lies outside a given vector space. We establish two significant properties of witnesses for co-VS reachability: they satisfy a pseudo-pumping lemma, and the lexicographically minimal witness has a special form. It follows that the co-VS reachability problem is in P. These reachability problems help us to show that the equivalence problem of weighted ODCAs over fields is in P by adapting the equivalence proof of deterministic real-time OCAs by B\"ohm et al. This is a step towards resolving the open question of the equivalence problem of weighted OCAs. Furthermore, we demonstrate that the regularity problem, the problem of checking whether an input weighted ODCA over a field is equivalent to some weighted automaton, is in P. Finally, we show that the covering and coverable equivalence problems for uninitialised weighted ODCAs are decidable in polynomial time. We also consider boolean ODCAs and show that the equivalence problem for (non-deterministic) boolean ODCAs is in PSPACE, whereas it is undecidable for (non-deterministic) boolean OCAs.Comment: 36 pages, 11 figure

Recombinant immunomodulating lentogenic or mesogenic oncolytic newcastle disease virus for treatment of pancreatic adenocarcinoma

Oncolytic Newcastle disease virus (NDV) might be a promising new therapeutic agent for the treatment of pancreatic cancer. We evaluated recombinant NDVs (rNDVs) expressing interferon (rNDV-hIFNβ-F0) or an IFN antagonistic protein (rNDV-NS1-F0), as well as rNDV with increased virulence (rNDV-F3aa) for oncolytic efficacy in human pancreatic adenocarcinoma cells. Expression of additional proteins did not hamper virus replication or cytotoxic effects on itsel

Serum Midkine, estimated glomerular filtration rate and chronic kidney disease-related events in elderly women: Perth Longitudinal Study of Aging Women

© 2020, The Author(s). Midkine (MDK), a heparin-binding growth factor cytokine, is involved in the pathogenesis of kidney diseases by augmenting leukocyte trafficking and activation. Animal models and small case control studies have implicated MDK as a pathological biomarker in chronic kidney diseases (CKD), however this is yet to be confirmed in prospective human studies. In a prospective study of 499 elderly, predominantly Caucasian women aged over 70 years the association between serum MDK collected in 1998, and renal function change and the risk of CKD-related hospitalisations and deaths at 5 and 14.5 years, respectively, was examined. Baseline serum MDK was not associated with 5-year change in estimated glomerular filtration rate using the CKD Epidemiology Collaboration creatinine and cystatin C equation (Standardised β = − 0.09, 95% confidence interval − 3.76–0.48, p = 0.129), 5-year rapid decline in renal function (odds ratio = 0.97, 95% confidence interval 0.46–2.02, p = 0.927) or the risk of 14.5-year CKD-related hospitalisations and deaths (hazard ratio = 1.27, 95% confidence interval.66–2.46, p = 0.470) before or after adjusting for major risk factors. In conclusion, in this cohort of elderly women with normal or mildly impaired renal function, serum MDK was not associated with renal function change or future CKD-related hospitalisations and deaths, suggesting that MDK may not be an early biomarker for progression of CKD

Thermochromic Metal Halide Perovskite Windows with Ideal Transition Temperatures

Urban centers across the globe are responsible for a significant fraction of energy consumption and CO2 emission. As urban centers continue to grow, the popularity of glass as cladding material in urban buildings is an alarming trend. Dynamic windows reduce heating and cooling loads in buildings by passive heating in cold seasons and mitigating solar heat gain in hot seasons. In this work, we develop a mesoscopic building energy model that demonstrates reduced building energy consumption when thermochromic windows are employed. Savings are realized across eight disparate climate zones of the United States. We use the model to determine the ideal critical transition temperature of 20 to 27.5 {\deg}C for thermochromic windows based on metal halide perovskite materials. Ideal transition temperatures are realized experimentally in composite metal halide perovskite film composed of perovskite crystals and an adjacent reservoir phase. The transition temperature is controlled by co-intercalating methanol, instead of water, with methylammonium iodide and tailoring the hydrogen-bonding chemistry of the reservoir phase. Thermochromic windows based on metal halide perovskites represent a clear opportunity to mitigate the effects of energy-hungry buildings

Investigation of SOA-based wavelength conversion at 80 Gb/s using bandpass filtering

This paper presents a simple and effective 80 Gb/s wavelength conversion scheme by using Cross Gain Modulation in a Semiconductor Optical Amplifiers (SOA) in conjunction with filtering the blue shifted component of the probe spectrum to give a non-inverted output signal