1,737 research outputs found

    Reduction Behaviour of Iron Ore Pellets

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    Demand of sponge iron and pre-reduced pellets for the manufacture of different varieties of steel is increasing day by day and new solid reductants based sponge iron plans are being commissioned. In the existing blast furnace an increase in production by at least 25 to 35% can be achieved by using pre reduced iron ore. Pre-reduced iron ore pellets have been established as a good substitute for steel scrap in an electric arc furnace which enhances the productivity of the arc furnace. A lot of investigations have been carried out on direct reduction process of iron oxides by carbonaceous materials, but little work has been done on the characterization of properties and reduction behavior of iron ore of. In the present project work, an attempt has been made to study the reduction behavior and kinetics of iron ore fired pellets. The effect of different reduction parameters such as temperature (850-1000ºC), time (15-120 minutes.), mixing of particles of different sizes at different ratios for pellet preparation etc. on the reduction behavior of iron ore pellets. These form the subject matter of the thesis. First chapter gives the introduction about the subject. It speaks about the need of DRI industry, scope, present status and future planning of DRI industry in India, world wise DRI production, etc. It gives a general idea of raw materials quality required for producing DRI, especially in Rotary Kiln. The second chapter deals with the literature survey. The third chapter deals with planning of experiments, selection of raw materials, preparation of samples, preparation of iron ore pellets, experimental procedure , evaluation of reduction and activation energies, etc. The results obtained and the discussions made from these observations have been outlined in chapter four. The result for fired iron ore pellets indicated an increase in degree of reduction with increase in reduction temperature (850-1000ºC) and time. The reduction kinetics of Zenith iron ore pellets were studied in temperature range of 850-1000ºC. The data were fitted on a differential model and the activation energies of reduction of pellets were calculated. Analysis of swelling behavior was also done. Results obtained from chapter four have been summarized in chapter five. Lastly, these conclusions have been followed by the list of references

    Multicarrier modulation with variable peak‐to‐average power ratio using partial fast Fourier transform

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/166180/1/cmu2bf01398.pd

    Paradoxical effect of coating on natural guar gum blended carbomer matrix systems for the neurological depressive disorders

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    Oral extended release products offer potential advantages in patient compliance and therapeutic outcomes like sustained blood levels with attenuation of adverse effects. In neuropsychiatric disorders like depression, most of the formulations serve a marketing objective rather than a clinical objective. The present investigation was aimed to develop a once daily sustained release formulation for delivery of an acid-labile, water soluble antidepressant, duloxetine HCl. The formulation was pragmatically designed using blend of natural and synthetic polymeric biomaterials that it releases the drug at alkaline pH in a sustained manner. The basic intention was to develop a tablet formulation with hydrophilic matrix core, using blend of release retarding natural biodegradable polymers such as guar gum, carbopol 71G-NF (a synthetic carbomer) and C-Pharm® gel. Barrier coating using HPMC-E5 was given to retard the initial release followed by enteric coating with HPMC-AS to prevent exposure of drug in acidic mileau of the stomach. The formulation exhibited desired release pattern and was described best-fit by Hixon-Crowell model. Stability analysis under stress conditions up to one month displayed good reproducibility. The matrix tablets successfully decreased the symptoms of depression (significant decrease in immobility time) in a rat forced swimming model. Pharmacokinetic data of the formulation revealed (tmax ~ 6 h, Cmax ~ 1157.58 ng/ml, mean AUCt~11145.04 ng*h/ml, and Ka~1.07h-1) good correlation in all animals.Keywords: Matrix tablets; Duloxetine HCl; Sustained release; Enteric coating; Hixon-crowell mode

    Paradoxical effect of coating on natural guar gum blended carbomer matrix systems for the neurological depressive disorders

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    Oral extended release products offer potential advantages in patient compliance and therapeutic outcomes like sustained blood levels with attenuation of adverse effects. In neuropsychiatric disorders like depression, most of the formulations serve a marketing objective rather than a clinical objective. The present investigation was aimed to develop a once daily sustained release formulation for delivery of an acid-labile, water soluble antidepressant, duloxetine HCl. The formulation was pragmatically designed using blend of natural and synthetic polymeric biomaterials that it releases the drug at alkaline pH in a sustained manner. The basic intention was to develop a tablet formulation with hydrophilic matrix core, using blend of release retarding natural biodegradable polymers such as guar gum, carbopol 71G-NF (a synthetic carbomer) and C-Pharm® gel. Barrier coating using HPMC-E5 was given to retard the initial release followed by enteric coating with HPMC-AS to prevent exposure of drug in acidic mileau of the stomach. The formulation exhibited desired release pattern and was described best-fit by Hixon-Crowell model. Stability analysis under stress conditions up to one month displayed good reproducibility. The matrix tablets successfully decreased the symptoms of depression (significant decrease in immobility time) in a rat forced swimming model. Pharmacokinetic data of the formulation revealed (tmax ~ 6 h, Cmax ~ 1157.58 ng/ml, mean AUCt~11145.04 ng*h/ml, and Ka~1.07h-1) good correlation in all animals.Keywords: Matrix tablets; Duloxetine HCl; Sustained release; Enteric coating; Hixon-crowell mode

    Leveraging AI for Predictive Migration Planning and Automated Data Transfer: Ensuring Optimal Cloud Resource Allocation and Data Integrity

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    This research paper explores the potential groundbreaking impact of Artificial Intelligence (AI) on the migration of applications from on-premises infrastructure to public cloud platforms. The utilization of predictive migration planning and automated data transfer highlights the potential of artificial intelligence (AI) in enhancing the efficiency of cloud resource allocation, safeguarding data integrity, and mitigating issues related to migration

    The Future of SAAS Startups: How AI Accelerates Market Research and Product Development

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    The paper explores the transformative role of Artificial Intelligence (AI) in accelerating market research and product development for Software as a Service (SaaS) startups. It delves into how AI can revolutionize traditional methods, offering faster and more accurate insights for market validation, competition analysis, and product optimization

    Economic analysis of trout feed production in Jammu and Kashmir, India

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    The Present study is an attempt to understand the economics of trout feed production in the state of Jammu and Kashmir. Trout feed production is capital intensive business which requires high initial capital investment. The results revealed that major fixed investment required in trout feed production was feed mill itself which accounted about 71.44 percent of the total investment. The cost and return analysis showed that the variable cost accounts 59.16 percent whereas fixed cost accounted 40.84 percent of the total cost respectively. Among the variable cost raw material was found out to be single most important factor which accounted about 56.37 percent of the total cost which was about 95.28 percent of the total variable cost. The average cost of production of trout feed was Rs.84.33/kg which ranged from Rs.78.45/kg in Kokarnag trout feed mill to Rs.90.2/kg in Manasbal trout feed mill but government has fixed selling price at Rs.73/Kg for the feed to maintain reasonable price level for private trout farmers. The availability and high price of raw material were found to be major constraints faced by feed producers. Economics analysis revealed that both the feed mills are operating at suboptimal level and there is need to utilize the feed mill to its full potential and export the surplus production to neighbouring state of Himachal Pradesh and other Himalayan states like Sikkim and Arunachal which will help the state fisheries department to generate extra income which can be used in other developmental activities

    Development and Mechanical Characterization of Ni-Cr Alloy Foam Using Ultrasonic-Assisted Electroplating Coating Technique

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    Metal foams and alloy foams are a novel class of engineering materials and have numerous applications because of their properties such as high energy absorption, light weight and high compressive strength. In the present study, the methodology adopted to develop a Ni-Cr alloy foam is discussed. Polyurethane (PU) foam of 40PPI (parts per inch) pore density was used as the precursor and coating techniques such as electroless nickel plating (ELN), ultrasonic-assisted electroplating of nickel (UAEPN), and pack cementation or chromizing were used to develop the Ni-Cr alloy foam. The surface morphology, strut thickness and minimum weight gain after each coating stage were evaluated. It was observed from the results that the adopted coating techniques did not damage the original ligament cross-section of the PU precursor. The minimum weight gain and the coating thickness after the UAEPN process were observed to be 42 g and 40–60 μm, respectively. The properties such as porosity percentage, permeability and compressive strength were evaluated. Finally, the pressure drop through the developed foam was estimated and verified to determine whether the developed foam can be used for filtering applications.Filipe Fernandes acknowledges the CEMMPRE (UIDB/00285/2020) and ARISE (LA/P/0112/2020) projects, sponsored by national funds through the FCT—Fundação para a Ciência e a Tecnologia

    Clinical Characteristics of Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome in North Indian Population of HIV/AIDS Patients Receiving HAART

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    Background & Objective. IRIS is an important complication that occurs during management of HIV-TB coinfection and it poses difficulty in diagnosis. Previous studies have reported variable incidence of IRIS. The present study was undertaken to describe the pattern of TB-associated IRIS using recently proposed consensus case-definitions for TB-IRIS for its use in resource-limited settings. Methods. A prospective analysis of ART-naïve adults started on HAART from November, 2008 to May, 2010 was done in a tertiary care hospital in north India. A total 224 patients divided into two groups, one with HIV-TB and the other with HIV alone, were followedup for a minimum period of 3 months. The diagnosis of TB was categorised as ‘‘definitive” and ‘‘probable”. Results. Out of a total of 224 patients, 203 completed followup. Paradoxical TB-IRIS occurred in 5 of 123 (4%) HIV-TB patients while 6 of 80 (7.5%) HIV patients developed ART-associated TB. A reduction in plasma viral load was significantly (P = .016) associated with paradoxical TB-IRIS. No identifiable risk factors were associated with the development of ART-associated TB. Conclusion. The consensus case-definitions are useful tools in the diagnosis of TB-associated IRIS. High index of clinical suspicion is required for an early diagnosis

    Bioaugmentation of biofloc system with enzymatic bacterial strains for high health and production performance of Penaeus indicus

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    Not AvailableThe beneficial effects of two probiotic bacterial strains Marinilactibacillus piezotolerans and Novosphingobium sp. during the culture of Indian white shrimp, Penaeus indicus, under biofloc and clear water system were evaluated. The experimental variation were CW1 (M. piezotolerans in clear water), BFT1 (biofloc + M. piezotolerans), CW2 (Novosphingobium sp. in clear water), BFT2 (biofloc + Novosphingobium sp.) and control (without bacterial strains and biofloc). Growth and survival considerably increased in probiotic bio-augmented treatments. Probiotic incorporation significantly improved water quality, especially ammonia reduction. Microbiota analysis from gut samples taken from different treatments revealed varied microbial population structure among clear water culture, biofloc culture and control. Proteobacteria and Firmicutes were the top phyla observed in the treatments which were significantly higher in bio-augmented systems than the control. Vibrio genera were predominantly observed in control and clear water system compared to that of biofloc systems. Immune genes were significantly altered in response to probiotic gut microbial supplementation than the control. Higher gene expression profile of important immune genes was observed in the biofloc reared shrimps. Expression of digestive enzyme related genes such as trypsin, chymotrypsin, cathepsin L, cathepsin B and alpha amylase were also upregulated significantly in probiotic supplementation especially in the biofloc treatments. Proteomic analysis of hepatopancreas of shrimps from different treatments was carried out by using 2D gel electrophoresis and MALDITOF analysis. The proteins were mostly related to growth and stress tolerance. Eukaryotic initiation factor 4E binding protein was expressed in all the groups and it was high in biofloc treated animals followed by animals treated solely with probiotics compared to those of control groups. The results concludes that biofloc already proved as an effective culture method for healthy shrimp production and supplementation of probiotic bacterial strains registered additional benefit for growth, survival, microbial, immunological status of P, indicus culture.Not Availabl
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